Abstract
In this paper, spatio-temporal characterization of axoplasmic fluid pressure has been performed with respect to ionic diffusivities. It has been observed that the propagation speed of axoplasmic fluid pressure is 19.5 m/s when longitudinal ionic diffusivities are considered along with ionic conductances at a temperature of \(18.5\,^\circ \text {C}\). However, this propagation speed of axoplasmic fluid pressure increases to 19.7 m/s when longitudinal ionic diffusivities are considered along with temperature-dependent diffusivities across the membrane at the same temperature of \(18.5\,^\circ \text {C}\). This is an important result where it has been possible to obtain axoplasmic pressure propagation velocities with respect to temperature-dependent ionic diffusivities. Also, based on the fact that increased intracellular pressure may lead to a number of neuronal disorders, temperature-dependent ionic diffusivities can be further fine-tuned to reduce the intracellular pressure and hence avoiding neuronal disorders.
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Bhatia, S., Singh, P., Sharma, P. (2019). Spatio-temporal Characterization of Axoplasmic Fluid Pressure with Respect to Ionic Diffusivities. In: Ray, K., Sharan, S., Rawat, S., Jain, S., Srivastava, S., Bandyopadhyay, A. (eds) Engineering Vibration, Communication and Information Processing. Lecture Notes in Electrical Engineering, vol 478. Springer, Singapore. https://doi.org/10.1007/978-981-13-1642-5_39
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