Abstract
The present study aims at evaluating the efficacy of commercially available RITA’s StarBurst® XL multi-tine electrode in attaining large size coagulation volumes (≥3 cm in diameter) during radiofrequency ablation (RFA) application. In vitro studies have been conducted on the cylindrical shaped polyacrylamide based tissue-mimicking phantom gels utilizing different active lengths of the multi-tine electrode, viz., 2 cm, 3 cm, 4 cm and 5 cm. A temperature-controlled RFA has been performed at a target tip temperature of 95 °C for 5 min. The variations in the power supply, the target tip temperature and the size of coagulation volume have been reported for different active lengths of the multi-tine electrode. The study revealed that the increase in active length of the multi-tine electrode results in more energy deposition and consequent rise in the coagulation volume during RFA procedure. Further, a simplified novel statistical correlation between the coagulation volume and active length of the multi-tine electrode has been proposed.
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References
Chu, K.F., Dupuy, D.E.: Thermal ablation of tumours: biological mechanisms and advances in therapy. Nature Reviews Cancer 14(3), 199–208 (2014).
Brace, C.: Thermal tumor ablation in clinical use. IEEE Pulse 2(5) 28–38 (2011).
Singh, S., Repaka, R.: Parametric sensitivity analysis of critical factors affecting the thermal damage during RFA of breast tumor. International Journal of Thermal Sciences 124, 366–374 (2018).
Gazelle, G.S., Goldberg, S.N., Solbiati, L., Livraghi, T.: Tumor ablation with radio-frequency energy 1. Radiology 217(3), 633–646 (2000).
Singh, S., Repaka, R.: Quantification of thermal injury to the healthy tissue due to imperfect electrode placements during radiofrequency ablation of breast tumor. ASME Journal of Engineering and Science in Medical Diagnostics and Therapy 1(1), 011002(1–10) (2018).
Ahmed, M., Brace, C.L., Lee, F.T., Goldberg, S.N.: Principles of and Advances in Percutaneous Ablation. Radiology 258(2), 351–369 (2011).
Zhang, B., Moser, M.A., Zhang, E.M., Luo, Y., Liu, C., Zhang, W.: A review of radiofrequency ablation: Large target tissue necrosis and mathematical modelling. Physica Medica 32(8), 961–971 (2016).
Miller, M.W., Ziskin, M.C.: Biological consequences of hyperthermia. Ultrasound in Medicine and Biology 15(8), 707–722 (1989).
Singh, S., Repaka, R.: Temperature-controlled radiofrequency ablation of different tissues using two-compartment models. International Journal of Hyperthermia 33(2), 122–134 (2017).
Singh, S., Repaka, R.: Effect of different breast density compositions on thermal damage of breast tumor during radiofrequency ablation. Applied Thermal Engineering 125, 443–451 (2017).
Bu-Lin, Z., Bing, H., Sheng-Li, K., Huang, Y., Rong, W., Jia, L.: A polyacrylamide gel phantom for radiofrequency ablation. International Journal of Hyperthermia 24(7), 568–576 (2008).
Singh, S., Repaka, R.: Numerical study to establish relationship between coagulation volume and target tip temperature during temperature-controlled radiofrequency ablation. Electromagnetic Biology and Medicine, 37(1), 13–22 (2018).
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Authors would like to acknowledge Indian Institute of Technology Ropar for providing essential infrastructure and necessary support to carry out the present research.
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Singh, S., Repaka, R. (2019). An in Vitro Phantom Study to Quantify the Efficacy of Multi-tine Electrode in Attaining Large Size Coagulation Volume During RFA. In: Lhotska, L., Sukupova, L., Lacković, I., Ibbott, G. (eds) World Congress on Medical Physics and Biomedical Engineering 2018. IFMBE Proceedings, vol 68/3. Springer, Singapore. https://doi.org/10.1007/978-981-10-9023-3_122
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DOI: https://doi.org/10.1007/978-981-10-9023-3_122
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