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Prenatal Diagnosis of Xeroderma Pigmentosum

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DNA Repair Disorders

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Abstract

Xeroderma pigmentosum (XP) is an autosomal recessively transmitted, intractable photosensitive disorder with deficient post-ultraviolet (UV) DNA repair. Patients with XP are highly predisposed to skin cancers on sun-exposed areas. Approximately 30% of XP patients develop progressive neurological abnormalities, although the cause of these changes is unknown.

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Authors and Affiliations

  1. Department of Dermatology, Osaka Medical College, Takatsuki, Osaka, Japan

    Shinichi Moriwaki

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  1. Shinichi Moriwaki
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Correspondence to Shinichi Moriwaki .

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Editors and Affiliations

  1. Department of Dermatology, Graduate School of Medicine, Kobe University, Kobe, Japan

    Chikako Nishigori

  2. Biosignal Research Center, Kobe University, Kobe, Japan

    Kaoru Sugasawa

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Moriwaki, S. (2019). Prenatal Diagnosis of Xeroderma Pigmentosum. In: Nishigori, C., Sugasawa, K. (eds) DNA Repair Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-10-6722-8_6

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  • DOI: https://doi.org/10.1007/978-981-10-6722-8_6

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-6721-1

  • Online ISBN: 978-981-10-6722-8

  • eBook Packages: MedicineMedicine (R0)

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