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Near-Infrared Spectroscopy for the Monitoring of Leucine Fermentation in Corynebacterium glutamicum

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Advances in Applied Biotechnology (ICAB 2016)

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 444))

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Abstract

Near-infrared spectroscopy has manifested its merits and great potentials in various areas. In the modern fermentation industries, near-infrared spectroscopy technique has been utilized for monitoring the quality of raw materials and products, and controlling the whole fermentation process. In this study, near-infrared spectroscopy was used to monitor the leucine fermentation by Corynebacterium glutamicum. A model for the prediction of leucine concentration was established, which had a R2 of 0.9905. The prediction values calculated using this model well fitted the true values, which suggested that the method could accurately predict and monitor the fermentation process.

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Acknowledgements

The authors are very grateful for the financial support from the Foundation (No.2016IM104) of Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education and Tianjin Key Lab of Industrial Microbiology (Tianjin University of Science & Technology), and the Foundation for Young Teachers of Tianjin University of Science and Technology (Grant No.2016LG11).

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Authors and Affiliations

  1. Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Key Lab of Industrial Microbiology, Tianjin University of Science and Technology, Tianjin, 300457, People’s Republic of China

    Hongbo Wei, Tuo Shi, Lihong Du, Qixin Chen, Yuechao Ma, Quanwei Zhang, Qian Ma & Ning Chen

Authors
  1. Hongbo Wei
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  2. Tuo Shi
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  3. Lihong Du
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  4. Qixin Chen
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  5. Yuechao Ma
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  6. Quanwei Zhang
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  7. Qian Ma
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  8. Ning Chen
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Corresponding author

Correspondence to Ning Chen .

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Editors and Affiliations

  1. College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China

    Hao Liu

  2. College of Life Sciences, Nankai University, Tianjin, China

    Cunjiang Song

  3. Institute of Biology Leiden, Leiden University, Leiden, The Netherlands

    Arthur Ram

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© 2018 Springer Nature Singapore Pte Ltd.

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Wei, H. et al. (2018). Near-Infrared Spectroscopy for the Monitoring of Leucine Fermentation in Corynebacterium glutamicum . In: Liu, H., Song, C., Ram, A. (eds) Advances in Applied Biotechnology. ICAB 2016. Lecture Notes in Electrical Engineering, vol 444. Springer, Singapore. https://doi.org/10.1007/978-981-10-4801-2_50

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