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Meta-Synthesis of Qualitative Research

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Handbook of Research Methods in Health Social Sciences

Abstract

A meta-synthesis of qualitative health research is a structured approach to analyzing primary data across the findings sections of published peer-reviewed papers reporting qualitative research. A meta-synthesis of qualitative research provides evidence for health care and service decision-making to inform improvements in both policy and practice. This chapter will provide an outline of the purpose of the meta-synthesis of qualitative health research, a historical overview, and insights into the value of knowledge generated from this approach. Reflective activities and references to examples from the literature will enable readers to:

  • Summarize methodological approaches that can be applied to the analysis of qualitative research.

  • Define the scope of and review question for a meta-synthesis of qualitative research.

  • Undertake a systematic literature search using standard tools and frameworks.

  • Examine critical appraisal tools for assessing the quality of research papers.

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References

  • Banning JH. Ecological triangulation: an approach for qualitative meta-synthesis. US Department of Education, School of Education, Colorado State University, Colorado; 2005.

    Google Scholar 

  • Barnett-Page E, Thomas J. Methods for the synthesis of qualitative research: a critical review, Evidence for Policy and Practice Information and Co-ordinating (EPPI) Centre, Social Science Research Unit Institute of Education, London 01/09; 2007.

    Google Scholar 

  • Bayliss K, Starling B, Raza K, Johansson EC, Zabalan C, Moore S, Skingle D, Jasinski T, Thomas S, Stack R. Patient involvement in a qualitative meta-synthesis: lessons learnt. Res Involv Engagem. 2016;2:18. https://doi.org/10.1186/s40900-016-0032-0.

    Article  Google Scholar 

  • Chatfield SL, DeBois K, Nolan R, Crawford H, Hallam JS. Hand hygiene among healthcare workers: a qualitative meta summary using the GRADE-CERQual process. J Infect Prev. 2017;18(3):104–20.

    Article  Google Scholar 

  • Cherryholmes CH. Notes on pragmatism and scientific realism. Educ Res. 1992;21(6):13–7.

    Article  Google Scholar 

  • Cooke A, Smith D, Booth A. Beyond PICO: the SPIDER tool for qualitative evidence synthesis. Qual Health Res. 2012;22(10):1435–43.

    Article  Google Scholar 

  • Crandell JL, Voils CI, Chang Y, Sandelowski M. Bayesian data augmentation methods for the synthesis of qualitative and quantitative research findings. Qual Quant. 2011;45(3):653–69.

    Article  Google Scholar 

  • Crotty M. The foundations of social research: meaning and perspective in the research process. St Leonards: Sage; 1998.

    Google Scholar 

  • Dawson AJ, Buchan J, Duffield C, Homer CS, Wijewardena K. Task shifting and sharing in maternal and reproductive health in low-income countries: a narrative synthesis of current evidence. Health Policy Plan. 2013;29(3):396–408.

    Article  Google Scholar 

  • Dawson A, Nkowane A, Whelan A. Approaches to improving the contribution of the nursing and midwifery workforce to increasing universal access to primary health care for vulnerable populations: a systematic review. Hum Resour Health. 2015;13:97. https://doi.org/10.1186/s12960-015-0096-1.

    Article  Google Scholar 

  • Denzin NK, Lincoln YS. The Sage handbook of qualitative research. Thousand Oaks: Sage; 2011.

    Google Scholar 

  • Elfenbein DM. Confidence crisis among general surgery residents: a systematic review and qualitative discourse analysis. JAMA Surg. 2016;151(12):1166–75.

    Article  Google Scholar 

  • Fegran L, Hall EO, Uhrenfeldt L, Aagaard H, Ludvigsen MS. Adolescents’ and young adults’ transition experiences when transferring from paediatric to adult care: a qualitative metasynthesis. Int J Nurs Stud. 2014;51(1):123–35.

    Article  Google Scholar 

  • France E, Ring N, Noyes J, Maxwell M, Jepson R, Duncan E, Turley R, Jones D, Uny I. Protocol-developing meta-ethnography reporting guidelines (eMERGe). BMC Med Res Methodol. 2015;15:103. https://doi.org/10.1186/s12874-015-0068-0.

    Article  Google Scholar 

  • France EF, Wells M, Lang H, Williams B. Why, when and how to update a meta-ethnography qualitative synthesis. Systematic reviews. 2016;5(44). https://doi.org/10.1186/s13643-13016-10218-13644. https://doi.org/10.1186/s13643-016-0218-4

  • Franzen SR, Chandler C, Lang T. Health research capacity development in low and middle income countries: reality or rhetoric? A systematic meta-narrative review of the qualitative literature. BMJ Open. 2017;7(1):e012332. https://doi.org/10.1136/bmjopen-2016-012332.

    Article  Google Scholar 

  • Glenton C, Colvin CJ, Carlsen B, Swartz A, Lewin S, Noyes J, Rashidian A. Barriers and facilitators to the implementation of lay health worker programmes to improve access to maternal and child health: qualitative evidence synthesis. Cochrane Database of Syst Rev. 2013;10. https://doi.org/10.1002/14651858.CD010414.pub2.

  • Gough D, Thomas J, Oliver S. Clarifying differences between review designs and methods. Syst Rev. 2012;1:28. https://doi.org/10.1186/2046-4053-1-28.

    Article  Google Scholar 

  • Greenhalgh T, Annandale E, Ashcroft R, Barlow J, Black N, Bleakley A, Boaden R, Braithwaite J, Britten N, Carnevale F. An open letter to The BMJ editors on qualitative research. BMJ. 2016;352:i563. https://doi.org/10.1136/bmj.i563.

    Article  Google Scholar 

  • Guba EG. The paradigm dialog. Newberry Park: Sage; 1990.

    Google Scholar 

  • Hannes K, Harden A. Multi-context versus context-specific qualitative evidence syntheses: combining the best of both. Res Synth Methods. 2011;2(4):271–8.

    Article  Google Scholar 

  • Hannes K, Lockwood C. Pragmatism as the philosophical foundation for the Joanna Briggs meta-aggregative approach to qualitative evidence synthesis. J Adv Nurs. 2011;67(7):1632–42.

    Article  Google Scholar 

  • Hannes K, Lockwood C. Qualitative evidence synthesis: choosing the right approach. West Sussex: Wiley-Blackwell; 2012.

    Google Scholar 

  • Hannes K, Macaitis K. A move to more systematic and transparent approaches in qualitative evidence synthesis: update on a review of published papers. Qual Res. 2012;12(4):402–42.

    Article  Google Scholar 

  • Hannes K, Pearson A. Obstacles to the implementation of evidence-based practice in Belgium: a worked example of meta-aggregation. In: Synthesizing qualitative research: choosing the right approach. Chichester: Wiley; 2012. p. 21–39.

    Chapter  Google Scholar 

  • Hannes K, Behrens J, Bath-Hextall F. There is no such thing as a one dimensional hierarchy of evidence: a critique and a perspective. Vienna, Austria: Paper presented at the Cochrane Colloquium; 2015.

    Google Scholar 

  • Harden A, Thomas J, Cargo M, Harris J, Pantoja T, Flemming K, Booth A, Garside R, Hannes K, Noyes J. Cochrane Qualitative and Implementation Methods Group guidance paper 4: methods for integrating qualitative and implementation evidence within intervention effectiveness reviews. J Clin Epidemiol. 2017;In Press, Accepted Manuscript. https://doi.org/10.1016/j.jclinepi.2017.11.029.

  • Harris JL, Booth A, Cargo M, Hannes K, Harden A, Flemming K, Garside R, Pantoja T, Thomas J, Noyes J. Cochrane Qualitative and Implementation Methods Group guidance series-paper 6: methods for question formulation, searching and protocol development for qualitative evidence synthesis. J Clin Epidemiol. 2017;In Press, Corrected Proof. https://doi.org/10.1016/j.jclinepi.2017.10.023.

  • Lewin S, Glenton C, Munthe-Kaas H, Carlsen B, Colvin CJ, Gülmezoglu M, Noyes J, Booth A, Garside R, Rashidian A. Using qualitative evidence in decision making for health and social interventions: an approach to assess confidence in findings from qualitative evidence syntheses (GRADE-CERQual). PLoS Med. 2015;12(10):e1001895. https://doi.org/10.1371/journal.pmed.

    Article  Google Scholar 

  • Martsolf DS, Draucker CB, Cook CB, Ross R, Stidham AW, Mweemba P. A meta-summary of qualitative findings about professional services for survivors of sexual violence. Qual Rep. 2010;15(3):489–506.

    Google Scholar 

  • Melendez-Torres GJ, Grant S, Bonell C. A systematic review and critical appraisal of qualitative metasynthetic practice in public health to develop a taxonomy of operations of reciprocal translation. Res Synth Methods. 2015;6(4):357–71.

    Article  Google Scholar 

  • Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097. https://doi.org/10.1371/journal.pmed.

    Article  Google Scholar 

  • Noblit GW, Hare RD. Meta-ethnography: synthesizing qualitative studies. Newbury Park: Sage; 1988.

    Book  Google Scholar 

  • Noyes J, Popay J. Directly observed therapy and tuberculosis: how can a systematic review of qualitative research contribute to improving services? A qualitative meta-synthesis. J Adv Nurs. 2007;57(3):227–43.

    Article  Google Scholar 

  • Noyes J, Hannes K, Booth A, Harris J, Harden A, Popay J, Pearson A, Cargo M, Pantoja T. Qualitative research and cochrane reviews. In: Higgins J, Green S, editors. Cochrane handbook for systematic reviews of interventions version 5.3.0. The Cochrane Collaboration. 2015. http://qim.cochrane.org/supplemental-handbook-guidance

  • Noyes J, Booth A, Flemming K, Garside R, Harden A, Lewin S, Pantoja T, Hannes K, Cargo M, Thomas J. Cochrane Qualitative and Implementation Methods Group guidance paper 2: methods for assessing methodological limitations, data extraction and synthesis, and confidence in synthesized qualitative findings. J Clin Epidemiol. 2017;In Press, Corrected Proof. https://doi.org/10.1016/j.jclinepi.2017.06.020.

  • Oishi A, Murtagh FE. The challenges of uncertainty and interprofessional collaboration in palliative care for non-cancer patients in the community: a systematic review of views from patients, carers and health-care professionals. Palliat Med. 2014;28(9):1081–98.

    Article  Google Scholar 

  • Oliver K, Rees R, Brady L-M, Kavanagh J, Oliver S, Thomas J. Broadening public participation in systematic reviews: a case example involving young people in two configurative reviews. Research Synthesis Methods. 2015;6(2):206–217. https://doi.org/10.1002/jrsm.1145

  • Onwuegbuzie AJ, Leech NL, Collins KM. Qualitative analysis techniques for the review of the literature. Qual Rep. 2012;17(28):1–28.

    Google Scholar 

  • Pawson R, Tilley N. Realistic evaluation. London: Sage; 1997.

    Google Scholar 

  • Rodríguez-Prat A, Balaguer A, Booth A, Monforte-Royo C. Understanding patients’ experiences of the wish to hasten death: an updated and expanded systematic review and meta-ethnography. BMJ Open. 2017;7(9):e016659. https://doi.org/10.1136/bmjopen-2017-016528.

    Article  Google Scholar 

  • Röing M, Holmström IK, Larsson J. A metasynthesis of phenomenographic articles on understandings of work among healthcare professionals. Qual Health Res. 2017;28(2):273–91. https://doi.org/10.1177/1049732317719433.

    Article  Google Scholar 

  • Sager F, Andereggen C. Dealing with complex causality in realist synthesis: the promise of qualitative comparative analysis. Am J Eval. 2012;33(1):60–78.

    Article  Google Scholar 

  • Sandelowski M, Barroso J. Handbook for synthesizing qualitative research. New York: Springer; 2006.

    Google Scholar 

  • Schreiber R, Crooks D, Stern PN. Qualitative meta-analysis. In: Morse M, editor. Completing a qualitative project: details and dialogue. Thousand Oaks: Sage; 1997. p. 311–26.

    Google Scholar 

  • Seymour KC, Addington-Hall J, Lucassen AM, Foster CL. What facilitates or impedes family communication following genetic testing for cancer risk? A systematic review and meta-synthesis of primary qualitative research. J Genet Couns. 2010;19(4):330–42.

    Article  Google Scholar 

  • Shaw R. Conducting literature reviews. In: Forreste MA, editor. Doing qualitative research in psychology: a practical guide. London: Sage; 2010. p. 39–56.

    Google Scholar 

  • Stansfield C, Thomas J, Kavanagh J. ‘Clustering’ documents automatically to support scoping reviews of research: a case study. Res Synth Methods. 2013;4(3):230–41.

    Google Scholar 

  • Thomas J, McNaught J, Ananiadou S. Applications of text mining within systematic reviews. Res Synth Methods. 2011;2(1):1–14.

    Article  Google Scholar 

  • Thomas J, O’Mara-Eves A, Brunton G. Using qualitative comparative analysis (QCA) in systematic reviews of complex interventions: a worked example. Syst Rev. 2014;3:67. https://doi.org/10.1186/2046-4053-3-67.

    Article  Google Scholar 

  • Thorne S, Jensen L, Kearney MH, Noblit G, Sandelowski M. Qualitative metasynthesis: reflections on methodological orientation and ideological agenda. Qual Health Res. 2004;14(10):1342–65.

    Article  Google Scholar 

  • Tomlin G, Borgetto B. Research pyramid: a new evidence-based practice model for occupational therapy. Am J Occup Ther. 2011;65(2):189–96.

    Article  Google Scholar 

  • Tong A, Flemming K, McInnes E, Oliver S, Craig J. Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ. BMC Med Res Methodol. 2012;12:181. https://doi.org/10.1186/471-2288-12-181.

    Article  Google Scholar 

  • Voils C, Hassselblad V, Crandell J, Chang Y, Lee E, Sandelowski M. A Bayesian method for the synthesis of evidence from qualitative and quantitative reports: the example of antiretroviral medication adherence. J Health Serv Res Policy. 2009;14(4):226–33.

    Article  Google Scholar 

  • Walder K, Molineux M. Occupational adaptation and identity reconstruction: a grounded theory synthesis of qualitative studies exploring adults’ experiences of adjustment to chronic disease, major illness or injury. J Occup Sci. 2017;24(2):225. https://doi.org/10.1080/14427591.2016.1269240.

    Article  Google Scholar 

  • Wong G, Greenhalgh T, Westhorp G, Pawson R. Development of methodological guidance, publication standards and training materials for realist and meta-narrative reviews: the RAMESES (Realist and Meta-narrative Evidence Syntheses–Evolving Standards) project. Health Serv Deliv Res. 2014;2(30):1. https://doi.org/10.3310/hsdr02300.

    Article  Google Scholar 

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Correspondence to Angela J. Dawson .

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Dawson, A.J. (2018). Meta-Synthesis of Qualitative Research. In: Liamputtong, P. (eds) Handbook of Research Methods in Health Social Sciences . Springer, Singapore. https://doi.org/10.1007/978-981-10-2779-6_112-1

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  • DOI: https://doi.org/10.1007/978-981-10-2779-6_112-1

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