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Juvenile Spondyloarthropathies

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Pediatric Rheumatology

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Abstract

To understand the concept of juvenile spondyloarthritis (SpA)

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References

  1. Prutki M, Tambic Bukovac L, Jelusic M, Potocki K, Kralik M, Malcic I. Retrospective study of juvenile spondyloarthropathies in Croatia over the last 11 years. Clin Exp Rheumatol. 2008;26:693–9.Epub 2008/09/19. eng.

    Google Scholar 

  2. Saurenmann RK, Rose JB, Tyrrell P, Feldman BM, Laxer RM, Schneider R, et al. Epidemiology of juvenile idiopathic arthritis in a multiethnic cohort: ethnicity as a risk factor. Arthritis Rheum. 2007;56:1974–84.Epub 2007/05/29. eng.

    Google Scholar 

  3. Solau-Gervais E, Robin C, Gambert C, Troller S, Danner S, Gombert B, et al. Prevalence and distribution of juvenile idiopathic arthritis in a region of Western France. Joint Bone Spine. 2010;77:47–9.Epub 2009/12/26. eng.

    Google Scholar 

  4. Zhang J, Huang F. The clinical features of juvenile onset spondyloarthropathies patients. Chin J Rheumatol. 2001;5:113–6.

    Google Scholar 

  5. Huang F, Zhang J, Shi G. Comparative study of juvenile and adult onset ankylosing spondylitis. Bull Post Grad Med Col. 1995;18:17–9.

    Google Scholar 

  6. Malleson PN, Fung MY, Rosenberg AM. The incidence of pediatric rheumatic diseases: results from the Canadian Pediatric Rheumatology Association Disease Registry. J Rheumatol. 1996;23:1981–7.Epub 1996/11/01. eng.

    Google Scholar 

  7. Agarwal M, Jariwala M, Sawhney S, Dinand V, FRI0351 Outcome of 267 JIA patients from a tertiary level indian pediatric rheumatology centre. Ann Rheum Dis. 2013;71(Suppl 3):433.

    Google Scholar 

  8. Jariwala M, Agarwal M, Sawhney S, Diagnostic Value of the Assessment of Spondyloarthropathy International Society (ASAS) Criteria for Children with Enthesitis Related Arthritis (ERA): A Single Center Study of 124 Patients. Arthritis Rheum. 2012;64:S718.

    Google Scholar 

  9. Kunjir V, Venugopalan A, Chopra A. Profile of Indian patients with juvenile onset chronic inflammatory joint disease using the ILAR classification criteria for JIA: a community-based cohort study. J Rheumatol. 2010;37:1756–62.Epub 2010/06/03. eng.

    Google Scholar 

  10. Seth V, Kabra SK, Semwal OP, Jain Y. Clinico-immunological profile in juvenile rheumatoid arthritis–an Indian experience. Indian J Pediatr. 1996;63:293–300.Epub 1996/05/01. eng.

    Google Scholar 

  11. Singh S, Salaria M, Kumar L, Minz R, Datta U, Sehgal S. Clinico-immunological profile of juvenile rheumatoid arthritis at Chandigarh. Indian Pediatr. 1999;36:449–54.Epub 2000/03/23. eng.

    Google Scholar 

  12. Braun J, Bollow M, Remlinger G, Eggens U, Rudwaleit M, Distler A, et al. Prevalence of spondyloarthropathies in HLA-B27 positive and negative blood donors. Arthritis Rheum. 1998;41:58–67.Epub 1998/01/20. eng.

    Google Scholar 

  13. Khan MA. Update on spondyloarthropathies. Ann Intern Med. 2002;136:896–907.Epub 2002/06/19. eng.

    Google Scholar 

  14. Chopra A, Patil J, Billempelly V, Relwani J, Tandle HS. Prevalence of rheumatic diseases in a rural population in western India: a WHO-ILAR COPCORD study. J Assoc Physicians India. 2001;49:240–6.Epub 2001/02/28. eng.

    Google Scholar 

  15. Hameed K, Gibson T. A comparison of the prevalence of rheumatoid arthritis and other rheumatic diseases amongst Pakistanis living in England and Pakistan. Br J Rheumatol. 1997;36:781–5.Epub 1997/07/01. eng.

    Google Scholar 

  16. Haq SA, Darmawan J, Islam MN, Uddin MZ, Das BB, Rahman F, et al. Prevalence of rheumatic diseases and associated outcomes in rural and urban communities in Bangladesh: a COPCORD study. J Rheumatol. 2005;32:348–53.Epub 2005/02/05. eng.

    Google Scholar 

  17. Joshi VL, Chopra A. Is there an urban-rural divide? Population surveys of rheumatic musculoskeletal disorders in the Pune region of India using the COPCORD Bhigwan model. J Rheumatol. 2009;36:614–22.Epub 2009/02/12. eng.

    Google Scholar 

  18. Gomez KS, Raza K, Jones SD, Kennedy LG, Calin A. Juvenile onset ankylosing spondylitis–more girls than we thought? J Rheumatol. 1997;24:735–7.Epub 1997/04/01. eng.

    Google Scholar 

  19. Agarwal M, Jariwala M, Sawhney S, Prakash R. THU0321 110 patients with enthesitis related arthritis: A demographic and clinical study from a tertiary level pediatric rheumatology centre in india. Ann Rheu Dis. 2013;71(Suppl 3):264.

    Google Scholar 

  20. Weiss PF, Beukelman T, Schanberg LE, Kimura Y, Colbert RA. Enthesitis-related arthritis is associated with higher pain intensity and poorer health status in comparison with other categories of juvenile idiopathic arthritis: the Childhood Arthritis and Rheumatology Research Alliance Registry. J Rheumatol.2012;39:2341–51. Pubmed Central PMCID: Pmc3513507, Epub 2012/10/17. eng.

    Google Scholar 

  21. Resnick D, Dwosh IL, Goergen TG, Shapiro RF, Utsinger PD, Wiesner KB, et al. Clinical and radiographic abnormalities in ankylosing spondylitis: a comparison of men and women. Radiology. 1976;119:293–7.Epub 1976/05/01. eng.

    Google Scholar 

  22. Rosenberg AM, Petty RE. A syndrome of seronegative enthesopathy and arthropathy in children. Arthritis Rheum. 1982;25:1041–7.Epub 1982/09/01.eng.

    Google Scholar 

  23. Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol. 2004;31:390–2.Epub 2004/02/05. eng.

    Google Scholar 

  24. van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 1984;27:361–8.Epub 1984/04/01. eng.

    Google Scholar 

  25. Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, et al. The European Spondyloarthropathy Study Group preliminary criteria for the classification of spondyloarthropathy. Arthritis Rheum. 1991;34:1218–27.Epub 1991/10/01. eng.

    Google Scholar 

  26. Prieur AM, Listrat V, Dougados M, Amor B. [Criteria for classification of spondyloarthropathies in children]. Arch Fr Pediatr. 1993;50:379–85.Epub 1993/05/01. Criteres de classification des spondylarthropathies chez les enfants. fre.

    Google Scholar 

  27. Kasapcopur O, Demirli N, Ozdogan H, Apelyan M, Caliskan S, Sever L, et al. Evaluation of classification criteria for juvenile-onset spondyloarthropathies. Rheumatol Int. 2005;25:414–8.Epub 2004/03/23. eng.

    Google Scholar 

  28. Rudwaleit M, van der Heijde D, Landewe R, Akkoc N, Brandt J, Chou CT, et al. The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann Rheum Dis. 2011;70:25–31.Epub 2010/11/27. eng.

    Google Scholar 

  29. Rudwaleit M, van der Heijde D, Landewe R, Listing J, Akkoc N, Brandt J, et al. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009;68:777–83.Epub 2009/03/20. eng.

    Google Scholar 

  30. Burgos-Vargas R. The assessment of the spondyloarthritis international society concept and criteria for the classification of axial spondyloarthritis and peripheral spondyloarthritis: a critical appraisal for the pediatric rheumatologist. Pediatr Rheumatol Online J. 2012;10:14. Pubmed Central PMCID: Pmc3403902, Epub 2012/06/02. eng.

    Google Scholar 

  31. Rubin LA, Amos CI, Wade JA, Martin JR, Bale SJ, Little AH, et al. Investigating the genetic basis for ankylosing spondylitis. Linkage studies with the major histocompatibility complex region. Arthritis Rheum. 1994;37:1212–20.Epub 1994/08/01. eng.

    Google Scholar 

  32. Liu Y, Li J, Chen B, Helenius H, Granfors K. Familial aggregation of ankylosing spondylitis in Southern China. J Rheumatol. 2001;28:550–3.

    Google Scholar 

  33. Benjamin R, Parham P. Guilt by association: HLA-B27 and ankylosing spondylitis. Immunol Today. 1990;11:137–42.Epub 1990/04/01. eng.

    Google Scholar 

  34. Colbert RA. HLA-B27 misfolding: a solution to the spondyloarthropathy conundrum? Mol Med Today. 2000;6:224–30.Epub 2000/06/07. eng.

    Google Scholar 

  35. Allen RL, O’Callaghan CA, McMichael AJ, Bowness P. Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure. J Immunol. 1999;162:5045–8.Epub 1999/05/05. eng.

    Google Scholar 

  36. Hinks A, Martin P, Flynn E, Eyre S, Packham J, Barton A, et al. Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis. Arthritis Res Ther. 2011;13:R12. Pubmed Central PMCID: Pmc3241356, Epub 2011/02/02. eng.

    Google Scholar 

  37. Mathieu A, Paladini F, Vacca A, Cauli A, Fiorillo MT, Sorrentino R. The interplay between the geographic distribution of HLA-B27 alleles and their role in infectious and autoimmune diseases: a unifying hypothesis. Autoimmun Rev. 2009;8:420–5.Epub 2009/02/03. eng.

    Google Scholar 

  38. Pacheco-Tena C, Alvarado De La Barrera C, Lopez-Vidal Y, Vazquez-Mellado J, Richaud-Patin Y, Amieva RI, et al. Bacterial DNA in synovial fluid cells of patients with juvenile onset spondyloarthropathies. Rheumatology (Oxford). 2001;40:920–7.Epub 2001/08/21. eng.

    Google Scholar 

  39. Myles A, Aggarwal A. Expression of toll-like receptors 2 and 4 is increased in peripheral blood and synovial fluid monocytes of patients with enthesitis-related arthritis subtype of juvenile idiopathic arthritis. Rheumatology (Oxford). 2011;50:481–8.Epub 2010/11/26. eng.

    Google Scholar 

  40. Stoll ML, Bhore R, Dempsey-Robertson M, Punaro M. Spondyloarthritis in a pediatric population: risk factors for sacroiliitis. J Rheumatol. 2010;37:2402–8. Pubmed Central PMCID: Pmc3093157, Epub 2010/08/05. eng.

    Google Scholar 

  41. Burgos-Vargas R, Vazquez-Mellado J, Cassis N, Duarte C, Casarin J, Cifuentes M, et al. Genuine ankylosing spondylitis in children: a case-control study of patients with early definite disease according to adult onset criteria. J Rheumatol. 1996;23:2140–7.Epub 1996/12/01. eng.

    Google Scholar 

  42. Sieper J, van der Heijde D, Landewe R, Brandt J, Burgos-Vagas R, Collantes-Estevez E, et al. New criteria for inflammatory back pain in patients with chronic back pain: a real patient exercise by experts from the Assessment of SpondyloArthritis international Society (ASAS). Ann Rheum Dis. 2009;68:784–8.Epub 2009/01/17. eng.

    Google Scholar 

  43. Flato B, Smerdel A, Johnston V, Lien G, Dale K, Vinje O, et al. The influence of patient characteristics, disease variables, and HLA alleles on the development of radiographically evident sacroiliitis in juvenile idiopathic arthritis. Arthritis Rheum. 2002;46:986–94.Epub 2002/04/16. eng.

    Google Scholar 

  44. Rachlis AC, Babyn PS, Lobo-Mueller E, Benseler SM, Stimec J, Anderson M et al. Whole body magnetic resonance imaging in juvenile spondyloarthritis: will it provide vital information compared to clinical exam alone? [abstract] Arthritis Rheum. 2011;63 Suppl 10:749.

    Google Scholar 

  45. Chang JH, McCluskey PJ, Wakefield D. Acute anterior uveitis and HLA-B27. Surv Ophthalmol. 2005;50:364–88.Epub 2005/06/22. eng.

    Google Scholar 

  46. Dotson JL, Hyams JS, Markowitz J, LeLeiko NS, Mack DR, Evans JS, et al. Extraintestinal manifestations of pediatric inflammatory bowel disease and their relation to disease type and severity. J Pediatr Gastroenterol Nutr. 2010;51:140–5.Epub 2010/05/11. eng.

    Google Scholar 

  47. Huppertz H, Voigt I, Muller-Scholden J, Sandhage K. Cardiac manifestations in patients with HLA B27-associated juvenile arthritis. Pediatr Cardiol. 2000;21:141–7.Epub 2000/04/08. eng.

    Google Scholar 

  48. Camiciottoli G, Trapani S, Ermini M, Falcini F, Pistolesi M. Pulmonary function in children affected by juvenile spondyloarthropathy. J Rheumatol. 1999;26:1382–6.Epub 1999/06/25. eng.

    Google Scholar 

  49. Burgos-Vargas R, Pacheco-Tena C, Vazquez-Mellado J. Juvenile-onset spondyloarthropathies. Rheum Dis Clin North Am. 1997;23:569–98.Epub 1997/08/01. eng.

    Google Scholar 

  50. Burgos-Vargas R, Clark P. Axial involvement in the seronegative enthesopathy and arthropathy syndrome and its progression to ankylosing spondylitis. J Rheumatol. 1989;16:192–7.Epub 1989/02/01. eng.

    Google Scholar 

  51. Cabral DA, Oen KG, Petty RE. SEA syndrome revisited: a longterm followup of children with a syndrome of seronegative enthesopathy and arthropathy. J Rheumatol. 1992;19:1282–5.Epub 1992/08/01. eng.

    Google Scholar 

  52. Hannu T. Reactive arthritis. Best Pract Res Clin Rheumatol. 2011;25:347–57.

    Google Scholar 

  53. Stoll ML, Punaro M. Psoriatic juvenile idiopathic arthritis: a tale of two subgroups. Curr Opin Rheumatol. 2011;23:437–43.Epub 2011/06/29. eng.

    Google Scholar 

  54. Butbul Aviel Y, Tyrrell P, Schneider R, Dhillon S, Feldman BM, Laxer R, et al. Juvenile Psoriatic Arthritis (JPsA): juvenile arthritis with psoriasis? Pediatr Rheumatol Online J. 2013;11:11. Pubmed Central PMCID: Pmc3622582, Epub 2013/03/19. eng.

    Google Scholar 

  55. Roberton DM, Cabral DA, Malleson PN, Petty RE. Juvenile psoriatic arthritis: followup and evaluation of diagnostic criteria. J Rheumatol. 1996;23:166–70.Epub 1996/01/01. eng.

    Google Scholar 

  56. Shore A, Ansell BM. Juvenile psoriatic arthritis–an analysis of 60 cases. J Pediatr. 1982;100:529–35.Epub 1982/04/01. eng.

    Google Scholar 

  57. Heiligenhaus A, Niewerth M, Ganser G, Heinz C, Minden K. Prevalence and complications of uveitis in juvenile idiopathic arthritis in a population-based nation-wide study in Germany: suggested modification of the current screening guidelines. Rheumatology (Oxford). 2007;46:1015–9.Epub 2007/04/04. eng.

    Google Scholar 

  58. Cardile S, Romano C. Current issues in pediatric inflammatory bowel disease-associated arthropathies. World J Gastroenterol. 2014;20:45–52. Pubmed Central PMCID: Pmc3886031, Epub 2014/01/15. eng.

    Google Scholar 

  59. Orchard TR, Wordsworth BP, Jewell DP. Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history. Gut. 1998;42:387–91.

    Google Scholar 

  60. Mamula P, Markowitz JE, Baldassano RN. Inflammatory bowel disease in early childhood and adolescence: special considerations. Gastroenterol Clin North Am. 2003;32:967–95. viii. Epub 2003/10/18. eng.

    Google Scholar 

  61. Malaviya AN, Sawhney S, Mehra NK, Kanga U. Seronegative arthritis in South Asia: an up-to-date review. Curr Rheumatol Rep. 2014;16:413.Epub 2014/02/12. eng.

    Google Scholar 

  62. Prakash S, Mehra NK, Bhargava S, Vaidya MC, Malaviya AN. Ankylosing spondylitis in North India: a clinical and immunogenetic study. Ann Rheum Dis. 1984;43:381–5.

    Google Scholar 

  63. Azouz EM, Duffy C. Juvenile spondyloarthropathies: clinical manifestations and medical imaging. Skeletal Radiol. 1995;24:399–408. English.

    Google Scholar 

  64. Rudwaleit M, Jurik AG, Hermann KG, Landewe R, van der Heijde D, Baraliakos X, et al. Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group. Ann Rheum Dis. 2009;68:1520–7.Epub 2009/05/21. eng.

    Google Scholar 

  65. Vendhan K, Sen D, Fisher C, Ioannou Y, Hall-Craggs MA. Inflammatory changes of the lumbar spine in children and adolescents with enthesitis-related arthritis: magnetic resonance imaging findings. Arthritis Care Res (Hoboken). 2014;66:40–6.Epub 2013/10/16. eng.

    Google Scholar 

  66. McGonagle D, Wakefield RJ, Tan AL, D’Agostino MA, Toumi H, Hayashi K, et al. Distinct topography of erosion and new bone formation in achilles tendon enthesitis: implications for understanding the link between inflammation and bone formation in spondylarthritis. Arthritis Rheum. 2008;58:2694–9.Epub 2008/09/02. eng.

    Google Scholar 

  67. Wallace CA, Ruperto N, Giannini E. Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. J Rheumatol. 2004;31:2290–4.Epub 2004/11/02. eng.

    Google Scholar 

  68. Sarma PK, Misra R, Aggarwal A. Outcome in patients with enthesitis related arthritis (ERA): juvenile arthritis damage index (JADI) and functional status. Pediatr Rheumatol Online J. 2008;6:18. Pubmed Central PMCID: Pmc2577669, Epub 2008/10/24. eng.

    Google Scholar 

  69. Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol. 1994;21:2286–91.Epub 1994/12/01. eng.

    Google Scholar 

  70. Calin A, Jones SD, Garrett SL, Kennedy LG. Bath ankylosing spondylitis functional index. Br J Rheumatol. 1995;34:793–4.Epub 1995/08/01. eng.

    Google Scholar 

  71. Rachlis AC, Batthish M, Wong B, Anderson M, Duvnjak M, Marcuz JA, et al. A24: validation of BASDAI and BASFI in children with spondyloarthritis. Arthritis Rheumatol. 2014;66 Suppl 11:S38.Epub 2014/03/29. eng.

    Google Scholar 

  72. Sieper J, Rudwaleit M, Baraliakos X, Brandt J, Braun J, Burgos-Vargas R, et al. The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis. 2009;68 Suppl 2:ii1–44.Epub 2009/05/14. eng.

    Google Scholar 

  73. Tse SM, Burgos-Vargas R, Colbert RA. Juvenile spondyloarthritis treatment recommendations. Am J Med Sci. 2012;343:367–70. Pubmed Central PMCID: Pmc3366270, Epub 2012/05/01. eng.

    Google Scholar 

  74. Kroon F, Landewé R, Dougados M, van der Heijde D. Continuous NSAID use reverts the effects of inflammation on radiographic progression in patients with ankylosing spondylitis. Ann Rheum Dis. 2012;24:2012.

    Google Scholar 

  75. Altan L, Bingol U, Karakoc Y, Aydiner S, Yurtkuran M, Yurtkuran M. Clinical investigation of methotrexate in the treatment of ankylosing spondylitis. Scand J Rheumatol. 2001;30:255–9. Epub 2001/12/01. eng.

    Google Scholar 

  76. Creemers MC, Franssen MJ, van de Putte LB, Gribnau FW, van Riel PL. Methotrexate in severe ankylosing spondylitis: an open study. J Rheumatol. 1995;22:1104–7. Epub 1995/06/01. eng.

    Google Scholar 

  77. Chen J, Liu C, Lin J. Methotrexate for ankylosing spondylitis. Cochrane Database Syst Rev. 2006;:Cd004524. Epub 2006/10/21. eng.

    Google Scholar 

  78. Burgos-Vargas R, Vázquez-Mellado J, Pacheco-Tena C, Hernández-Garduño A, Goycochea-Robles MV. A 26 week randomised, double blind, placebo controlled exploratory study of sulfasalazine in juvenile onset spondyloarthropathies. Ann Rheum Dis. 2002;61:941–2.

    Google Scholar 

  79. Huang JL, Chen LC. Sulphasalazine in the treatment of children with chronic arthritis. Clin Rheumatol. 1998;17:359–63. Epub 1998/11/07. eng.

    Google Scholar 

  80. van Rossum MA, Fiselier TJ, Franssen MJ, Zwinderman AH, ten Cate R, van Suijlekom-Smit LW, et al. Sulfasalazine in the treatment of juvenile chronic arthritis: a randomized, double-blind, placebo-controlled, multicenter study. Dutch Juvenile Chronic Arthritis Study Group. Arthritis Rheum. 1998;41:808–16. Epub 1998/05/20. eng.

    Google Scholar 

  81. Braun J, Zochling J, Baraliakos X, Alten R, Burmester G, Grasedyck K, et al. Efficacy of sulfasalazine in patients with inflammatory back pain due to undifferentiated spondyloarthritis and early ankylosing spondylitis: a multicentre randomised controlled trial. Ann Rheum Dis. 2006;65:1147–53. Pubmed Central PMCID: Pmc1798286, Epub 2006/04/12. eng.

    Google Scholar 

  82. Dougados M, Boumier P, Amor B. Sulphasalazine in ankylosing spondylitis: a double blind controlled study in 60 patients. Br Med J (Clin Res Ed). 1986;293:911–4. Pubmed Central PMCID: Pmc1341708, Epub 1986/10/11. eng.

    Google Scholar 

  83. Dougados M, Maetzel A, Mijiyawa M, Amor B. Evaluation of sulphasalazine in the treatment of spondyloarthropathies. Ann Rheum Dis. 1992;51:955–8. Pubmed Central PMCID: Pmc1004802, Epub 1992/08/01. eng.

    Google Scholar 

  84. Suschke HJ. Treatment of juvenile spondylarthritis and reactive arthritis with sulfasalazine. Monatsschr Kinderheilkd. 1992;140:658–60. Epub 1992/09/01. Die Behandlung der juvenilen Spondylarthritis und der reaktiven Arthritis mit Sulfasalazin. ger.

    Google Scholar 

  85. Silverman E, Mouy R, Spiegel L, Jung LK, Saurenmann RK, Lahdenne P, et al. Leflunomide or methotrexate for juvenile rheumatoid arthritis. N Engl J Med. 2005;352:1655–66. Epub 2005/04/22. eng.

    Google Scholar 

  86. Dongxu L, Zongwen S, Shanyu C. A clinical study on leflunomide in the treatment of refractory ankylosing spondylitis with peripheral arthritis. Acta Universitatis Medicinalis Anhui. 2011;10:021.

    Google Scholar 

  87. Zhang GL, Huang F, Zhang JL, Li XF. A clinical study of leflunomide and methotrexate therapy in psoriatic arthritis. Zhonghua Nei Ke Za Zhi. 2009;48:570–4. Epub 2009/12/05. chi.

    Google Scholar 

  88. Burgo-Vargas R, Gutierrez-Suarez C-VJ. A 3-month, double-blind, placebo-controlled, randomized trial of infliximab in juvenile-onset spondyloarthritis (SpA) and a 52-week open extension. Clin Exper Rheumatol. 2008;26:745.

    Google Scholar 

  89. Hugle B, Burgos-Vargas R, Inman RD, O’Shea F, Laxer RM, Stimec J, et al. Long-term outcome of anti-tumor necrosis factor alpha blockade in the treatment of juvenile spondyloarthritis. Clin Exp Rheumatol. 2014;32:424–31. Epub 2014/01/07. eng.

    Google Scholar 

  90. Horneff G, Burgos-Vargas R, Constantin T, Foeldvari I, Vojinovic J, Chasnyk VG, et al. Efficacy and safety of open-label etanercept on extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis and psoriatic arthritis: part 1 (week 12) of the CLIPPER study. Ann Rheum Dis. 2014;73:1114–22. Pubmed Central PMCID: Pmc4033142, Epub 2013/05/23. eng.

    Google Scholar 

  91. Sulpice M, Deslandre CJ, Quartier P. Efficacy and safety of TNFalpha antagonist therapy in patients with juvenile spondyloarthropathies. Joint Bone Spine. 2009;76:24–7. Epub 2008/12/17. eng.

    Google Scholar 

  92. Horneff G, Fitter S, Foeldvari I, Minden K, Kuemmerle-Deschner J, Tzaribacev N, et al. Double-blind, placebo-controlled randomized trial with adalimumab for treatment of juvenile onset ankylosing spondylitis (JoAS): significant short term improvement. Arthritis Res Ther. 2012;14:R230. Pubmed Central PMCID: Pmc3580542, Epub 2012/10/26. eng.

    Google Scholar 

  93. Burgos-Vargas R, Tse SM, Horneff G, Pangan AL, Unnebrink K, Anderson JK. A3: efficacy and safety of adalimumab in pediatric patients with enthesitis related arthritis. Arthritis Rheumatol. 2014;66 Suppl 11:S4. Epub 2014/03/29. eng.

    Google Scholar 

  94. Beukelman T, Patkar NM, Saag KG, Tolleson-Rinehart S, Cron RQ, DeWitt EM, et al. 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res (Hoboken). 2011;63:465–82. Pubmed Central PMCID: 3222233, Epub 2011/04/01. eng.

    Google Scholar 

  95. Braun J, van den Berg R, Baraliakos X, Boehm H, Burgos-Vargas R, Collantes-Estevez E, et al. 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis. 2011;70:896–904. Pubmed Central PMCID: Pmc3086052, Epub 2011/05/05. eng.

    Google Scholar 

  96. Stone M, Warren RW, Bruckel J, Cooper D, Cortinovis D, Inman RD. Juvenile-onset ankylosing spondylitis is associated with worse functional outcomes than adult-onset ankylosing spondylitis. Arthritis Rheum. 2005;53:445–51. Epub 2005/06/04. eng.

    Google Scholar 

  97. Flato B, Hoffmann-Vold AM, Reiff A, Forre O, Lien G, Vinje O. Long-term outcome and prognostic factors in enthesitis-related arthritis: a case-control study. Arthritis Rheum. 2006;54:3573–82. Epub 2006/11/01. eng.

    Google Scholar 

  98. Flato B, Aasland A, Vinje O, Forre O. Outcome and predictive factors in juvenile rheumatoid arthritis and juvenile spondyloarthropathy. J Rheumatol. 1998;25:366–75. Epub 1998/03/07. eng.

    Google Scholar 

  99. Minden K, Kiessling U, Listing J, Niewerth M, Doring E, Meincke J, et al. Prognosis of patients with juvenile chronic arthritis and juvenile spondyloarthropathy. J Rheumatol. 2000;27:2256–63. Epub 2000/09/16. eng.

    Google Scholar 

  100. Burgos-Vargas R. A case of childhood-onset ankylosing spondylitis: diagnosis and treatment. Nat Clin Pract Rheumatol. 2009;5:52–7.

    Google Scholar 

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Authors and Affiliations

  1. Division of Rheumatology, Sir Ganga Ram Hospital, Old Rajinder Nagar, New Delhi, 110060, India

    Mehul Jariwala

  2. Department of Rheumatology, Faculty of Medicine, Hospital General de México, Universidad Nacional Autónoma de México, Dr. Balmis 148, Colonia Doctores, México, DF, 06720, Mexico

    Ruben Burgos-Vargas

Authors
  1. Mehul Jariwala
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  2. Ruben Burgos-Vargas
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Correspondence to Mehul Jariwala .

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Editors and Affiliations

  1. Pediatric Rheumatology Division Institute of Child Health, Sir Ganga Ram Hospital, New Delhi, India

    Sujata Sawhney

  2. Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

    Amita Aggarwal

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Jariwala, M., Burgos-Vargas, R. (2017). Juvenile Spondyloarthropathies. In: Sawhney, S., Aggarwal, A. (eds) Pediatric Rheumatology. Springer, Singapore. https://doi.org/10.1007/978-981-10-1750-6_19

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  • DOI: https://doi.org/10.1007/978-981-10-1750-6_19

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