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Drug-Induced Tardive Dyskinesia

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Current Developments in Psychopharmacology

Part of the book series: Current Developments in Psychopharmacology ((CDPS,volume 6))

Abstract

Drug-induced tardive dyskinesia, which occurs in the course of long-term administration of psychotropic drugs, especially neuroleptics, and persists for years even after drug removal, began to be reported in the late 1950s. Since then, more than 100 investigations on this subject have been described. And it is estimated that 10 to 30 percent of long-term hospitalized psychiatric patients in Europe and North America exhibit tardive dyskinesia, whereas 5 to 20 percent of patients exhibit this syndrome in Japan. These findings suggest that the manifestation of tardive dyskinesia will become a serious problem in the investigation of psychotropic drug treatment.

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  1. Hitoshi Itoh
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Editors and Affiliations

  1. Department of Psychology, Queens College of the City University of New York, Flushing, N.Y., USA

    Walter B. Essman

  2. Department of Biochemistry, Queens College of the City University of New York, Flushing, N.Y., USA

    Walter B. Essman

  3. Section of Neuropsychopharmacology, Mario Negri Institute for Pharmacological Research, Milan, Italy

    Luigi Valzelli

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Itoh, H. (1981). Drug-Induced Tardive Dyskinesia. In: Essman, W.B., Valzelli, L. (eds) Current Developments in Psychopharmacology. Current Developments in Psychopharmacology, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-8123-5_4

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