Abstract
There are many data supporting the view that polymorphonuclears (PMNs) may play a major role in the pathogenesis of psoriasis. PMNs are a constant finding in the stratum corneum (Munro microabscesses) in fully developed lesions, and appear also in the corium of earliest psoriatic papules.1,2 Increased activity of PMNs in psoriasis, as measured by Chemotaxis assay,3,4 enzyme level,5 superoxide anion production,6,7 and enhanced adherence favour their direct involvement in the formation of skin lesions.
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Langner, A., Fraczykowska, M., Jablońska, S., Szymańczyk, J., Chorzelski, T. (1984). The Effect of Etretinate on Chemotactic Activity of Polymorphonuclear Leukocytes in Various Forms of Psoriasis. In: Cunliffe, W.J., Miller, A.J. (eds) Retinoid Therapy. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-6349-1_16
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DOI: https://doi.org/10.1007/978-94-011-6349-1_16
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