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Production of (Recombinant) Baculoviruses in Insect-Cell Bioreactors

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Recent Advances in Biotechnology

Part of the book series: NATO ASI Series ((NSSE,volume 210))

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Abstract

Various aspects of (recombinant) baculovirus production in insect-cell cultures are discussed. After a general introduction, the biology and the factors affecting the replication of the virus are covered. Then design considerations and production levels are discussed in view of large-scale production. Finally, the first attempts in modelling this complex process are treated.

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Authors and Affiliations

  1. Department of Food Science, Food and Bioprocess Engineering Group, Agricultural University Wageningen, P.O. Box 8129, 6700 EV, Wageningen, The Netherlands

    J. Tramper, F. L. J. van Lier & C. D. de Gooijer

  2. Department of Virology, P.O. Box 8045, 6700 EM, Wageningen, The Netherlands

    M. Kool & J. M. Vlak

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  1. J. Tramper
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  2. F. L. J. van Lier
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  3. M. Kool
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  4. C. D. de Gooijer
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  5. J. M. Vlak
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Editors and Affiliations

  1. Department of Chemical Engineering, Ege University, Izmir, Turkey

    Fazilet Vardar-Sukan

  2. Biotechnology Centre and Department of Food Engineering, Ege University, Izmir, Turkey

    Ş. Suha Sukan

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Tramper, J., van Lier, F.L.J., Kool, M., de Gooijer, C.D., Vlak, J.M. (1992). Production of (Recombinant) Baculoviruses in Insect-Cell Bioreactors. In: Vardar-Sukan, F., Sukan, Ş.S. (eds) Recent Advances in Biotechnology. NATO ASI Series, vol 210. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2468-3_12

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  • DOI: https://doi.org/10.1007/978-94-011-2468-3_12

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