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Renal immaturity causes taurine depletion in very low birth weight infants fed with prolonged total parenteral nutrition

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Amino Acids

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Abstract

Taurine is a ß amino acid, whose functions include neuromodulation, cell membrane stabilization, antioxidation, detoxification, bile acid conjugation and osmoregulation [1], and is regarded as essential for normal brain and retinal development [2]. Taurine depletion in early life causes degeneration of retinal photoreceptors, CNS abnormalities and growth depression in young animals [1] and atypical electroretinograms in children [3] and auditory brainstem evoked responses in preterm infants [4].

This study is supported in part by National Institutes of Health Grants P30AM35747 and DK-37223.

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Author information

Authors and Affiliations

  1. Division of Pediatric Nephrology, Department of Pediatrics, University of Tennessee, Memphis, TN, USA

    Israel Zelikovic

  2. Department of Pediatrics, University of Tennessee, Memphis, TN, USA

    Russell W. Chesney

  3. Division of Pediatric Nephrology, Department of Pediatrics, University of Wisconsin, Madison, WI, USA

    Aaron L. Friedman

  4. Division of Neonatology, Department of Pediatrics, University of California, Davis, Sacramento, CA, USA

    Charles E. Ahlfors

Authors
  1. Israel Zelikovic
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  2. Russell W. Chesney
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  3. Aaron L. Friedman
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  4. Charles E. Ahlfors
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Editor information

Editors and Affiliations

  1. Department of Pediatrics, University of Vienna, A-1090, Vienna, Austria

    Gert Lubec

  2. T. H. Morgan School of Biological Sciences and The Graduate Center for Toxicology, University of Kentucky, 40506-0225, Lexington, Kentucky, USA

    Gerald A. Rosenthal

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© 1990 ESCOM Science Publishers B.V.

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Zelikovic, I., Chesney, R.W., Friedman, A.L., Ahlfors, C.E. (1990). Renal immaturity causes taurine depletion in very low birth weight infants fed with prolonged total parenteral nutrition. In: Lubec, G., Rosenthal, G.A. (eds) Amino Acids. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2262-7_137

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  • DOI: https://doi.org/10.1007/978-94-011-2262-7_137

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-72199-04-1

  • Online ISBN: 978-94-011-2262-7

  • eBook Packages: Springer Book Archive

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