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Deamidation within a γ-Gliadin-Derived Peptide Enhances Its Recognition by Serum Antibodies of CD Patients

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Peptides: The Wave of the Future

Part of the book series: American Peptide Symposia ((APSY,volume 7))

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Abstract

Coeliac disease (CD) or gluten sensitive enteropathy is an autoimmune disease mainly affecting the proximal small intestine [1]. It is caused in susceptible persons by the ingestion of certain cereal proteins, i.e. gliadins and glutenins from wheat. The intestinal mucosa shows characteristic lesions resulting in malabsorption of nutrients.

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References

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Author information

Authors and Affiliations

  1. Institute of Organic Chemistry, University of Tuebingen, Tuebingen, 72076, Germany

    Florian v.d. Muelbe, Dietmar G. Schmid, Günther Jung & Burkhard Fleckenstein

  2. Institute of Cell Biology, University of Tuebingen, Tuebingen, 72076, Germany

    Toni Weinschenk

  3. Institute of Clinical Chemistry and Pathobiochemistry, University of Leipzig, Leipzig, Germany

    Thomas Mothes, Holm Uhlig & A. A. Osman

Authors
  1. Florian v.d. Muelbe
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  2. Thomas Mothes
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  3. Holm Uhlig
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  4. A. A. Osman
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  5. Toni Weinschenk
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  6. Dietmar G. Schmid
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  7. Günther Jung
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  8. Burkhard Fleckenstein
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Editor information

Editors and Affiliations

  1. Spyder Instruments, Inc. and Illumina, Inc., 9885 Towne Centre Drive, 92121, San Diego, CA, USA

    Michal Lebl

  2. Torrey Pines Institute for Molecular Studies, Mixture Sciences, Inc., 3550 General Atomics Court, 92121, San Diego, CA, USA

    Richard A. Houghten

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© 2001 Springer Science+Business Media Dordrecht

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v.d. Muelbe, F. et al. (2001). Deamidation within a γ-Gliadin-Derived Peptide Enhances Its Recognition by Serum Antibodies of CD Patients. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_485

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  • DOI: https://doi.org/10.1007/978-94-010-0464-0_485

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3905-5

  • Online ISBN: 978-94-010-0464-0

  • eBook Packages: Springer Book Archive

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