Hypertension Secondary to Thyroid Dysfunction

Abstract

Numerous papers have suggested that decreased thyroid function would ameliorate or slow the development of experimental hypertension. In addition, a number of papers have documented decrease in one parameter or another of thyroid function in various types of experimental hypertension. The clinical literature has suggested that hypothyroidism may be associated with hypertension which certainly would not be anticipated from the animal studies. There is relatively little about any causal role of hyperthyroidism in the development of diastolic hypertension in humans. This article will first review the clinical literature on hypothyroidism and hyperthyroidism and then discuss the experimental literature.