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Pediatric liver transplantation

  • Chapter
Progress in Liver Transplantation

Part of the book series: Developments in Gastroenterology ((DIGA,volume 6))

Abstract

The value of cadaveric organ transplantation in infants and children has been often questioned because of the unsatisfactory survival and high morbidity associated with the conventional immunosuppressive regimen which includes azathio- prine and prednisone, with or without antilymphocyte globulin. Even after so-called ‘successful’ transplantation the quality of life has been degraded too often by the side effects of high-dose steroid therapy, such as Cushingoid changes, growth retardation and osteoporosis.

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References

  1. Borel JF, Feurer C, Gubler HU, Stahelin H: Biological effects of cyclosporin A; a new anti-lymphocytic agent. Agents Act 6:468–475, 1976.

    Article  CAS  Google Scholar 

  2. Borel JF, Feurer C, Magnee C, Stahelin H: Effects of the new antilymphocytic peptide cyclosporin A in animals. Immunology 32:1017–1025, 1977.

    PubMed  CAS  Google Scholar 

  3. Calne R, White DJG, Thiru S, Evans DB, McMaster P, Dunn DC: Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet 2:1323–1327, 1978.

    Article  PubMed  CAS  Google Scholar 

  4. Calne RY, Rolles K, White DJG, Thiru S, Evans DB, McMaster P, Dun DC, Craddock GN, Henderson RG, Aziz S, Lewis P: Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs; 32 kidneys, 2 pancreases, 2 livers. Lancet 2:1033–1036, 1979.

    Article  PubMed  CAS  Google Scholar 

  5. Starzl TE, Wei R III, Iwatsuki S, Klintmalm GBG, Schröter GP, Koep LJ, Iwaki Y, Teraskai PI, Porter KA: The use of cyclosporin A and prednisone in cadaveric kidney transplantation. Surg Gynecol Obset 151:17–26, 1980.

    CAS  Google Scholar 

  6. Starzl TE, Klintmalm GBG, Weil R III, Porter KA, Iwatsuki S, Schröter GP, Fernandez-Bueno C, MacHugh N: Cyclosporin A and steroid therapy in 66 cadaver kidney recipients. Surg Gynecol Obstet 153:486–494, 1981.

    PubMed  CAS  Google Scholar 

  7. Starzl TE, (With the assistance of CW Putnam): Experience in hepatic transplantation. Philadelphia, WB Saunders, 1969.

    Google Scholar 

  8. Starzl TE, Porter KA, Putnam CW, Schröter GPJ, Halgrimson CG, Weil R III, Hoelscher M, Reid HAS: Orthotopic liver transplantation in 93 patients. Surg Gynecol Obstet 142:487–505, 1976.

    PubMed  CAS  Google Scholar 

  9. Starzl TE, Koep LJ, Halgrimson CG, Hood J, Schröter GPJ, Porter KA, Weil R III: Fifteen years of clinical liver transplantation. Gastroenterology 77:375–388, 1979.

    PubMed  CAS  Google Scholar 

  10. Iwatsuki S, Klintmalm GBG, Starzl TE: Total hepatectomy and liver replacement (Orthotopic liver transplantation) for primary hepatic malignancy. World J Surg 6:81–85, 1982.

    Article  PubMed  CAS  Google Scholar 

  11. Calne RY: Liver transplantation for liver cancer. World J Surg 6:76–80, 1982.

    Article  PubMed  CAS  Google Scholar 

  12. Starzl TE, Iwatsuki S, Van Thiel DH, Gartner JC, Zitelli BJ, Malatack JJ, Schade RR, Shaw BW Jr, Hakala TR, Rosenthal JT, Porter KA: Evolution of liver transplantation. Hepatology 2:614–636, 1982.

    Article  PubMed  CAS  Google Scholar 

  13. Starzl TE, Marchioro TL. Huntley RT, Rifkind D, Rowlands DT Jr, Dickinson TC, Waddell WR: Experimental and clinical homotransplantation of the liver. Ann NY Acad Sei 120:739–765, 1964.

    CAS  Google Scholar 

  14. Starzl TE, Marchioro TL, Faris TD, McCardle RJ, Iwasaki Y: Avenues of future research in homotransplantation of the liver: With particular reference to hepatic supportive procedures, antilymphocyte serum, and tissue typing. Am J Surg 112:391–400, 1966.

    Article  PubMed  CAS  Google Scholar 

  15. Starzl TE: Experience in renal transplantation. Philadelphia, WB Saunders, 1964.

    Google Scholar 

  16. Starzl TE, Putnam CW, Halgrimson CG, Schröter GP, Martineau G, Launois B, Corman JL, Penn I, Booth AS Jr, Porter KA, Groth CG: Cyclophosphamide and whole organ transplantation in humans. Surg Gynecol Obstet 133:981–999, 1971.

    PubMed  CAS  Google Scholar 

  17. Starzl TE, Iwatsuki S, Klintmalm GBG, Schröter GPJ, Weil R III, Koep LJ, Porter KA: Liver transplantation, 1980, with particular reference to Cyclosporin A. Transplant Proc 13:281–285, 1981.

    PubMed  CAS  Google Scholar 

  18. Starzl TE, Klintmalm GBG, Porter KA, Iwatsuki S, Schröter GP: Liver transplantation with use of Cyclosporin A and prednisone. N Engl J Med 305:266–269, 1981.

    Article  PubMed  CAS  Google Scholar 

  19. Shaw BW Jr, Hakala T, Rosenthal JT, Iwatsuki S, Broznick B, Starzl TE: Combination donor hepatectomy and nephrectomy and early functional results of allografts. Surg Gynecol Obstet 155:321–325, 1982.

    PubMed  Google Scholar 

  20. Shaw BW Jr, Rosenthal JT, Griffith BF, Hardesty RL, Broznik B, Hakala T, Bahnson HT, Starzl TE: Techniques for combined procurement of hearts and kidneys with satisfactory early function of renal allografts. Surg Gynecol Obstet 157:261–264, 1983.

    PubMed  Google Scholar 

  21. Shaw BW Jr, Iwatsuki S, Starzl TE: Alternative methods of hepatic graft arterialization. Surg Gynecol Obstet 159:491–493, 1984.

    Google Scholar 

  22. Starzl TE, Koep LJ, Weil R III, Halgrimson CG: Development of a suprahepatic recipient vena cava cuff for liver transplantation. Surg Gynecol Obstet 149:76–77, 1979.

    Google Scholar 

  23. Starzl TE, Groth CG, Brettschneider L: An everting technique for intraluminal vascular suturing. Surg Gynecol Obstet 127:125–126, 1979.

    Google Scholar 

  24. Starzl TE, Iwatsuki S, Shaw BW Jr: A ‘Growth Factor’ in fine vascular anastomoses. Surg Gynecol Obstet 159:164–166, 1984.

    PubMed  CAS  Google Scholar 

  25. Starzl TE, Putnam CW, Hansbrough JF, Porter KA, Reid HAS: Biliary complications after liver transplantation; with special reference to the biliary cast syndrome and techniques of secondary duct repair. Surgery 81:212–221, 1976.

    Google Scholar 

  26. Iwatsuki S, Shaw BW Jr, Starzl TE: Biliary tract complications in liver transplantation under cyclosporine-steroid therapy. Transplant Proc 15:1288–1291, 1983.

    Google Scholar 

  27. Martineau G, Porter KA, Corman J, Launois B, Schröter G, Palmer W, Putnam CW, Groth CG, Halgrimson CG, Penn I, Starzl TE: Delayed biliary duct obstruction after orthotopic liver transplantation. Surgery 72:604–610, 1972.

    PubMed  CAS  Google Scholar 

  28. Starzl TE, Koep LJ, Porter KA, Schröter GPJ, Weil R III, Hartley RB, Halgrimson CG: Decline in survival after liver transplantation. Arch Surg 115:815–819, 1980.

    Article  PubMed  CAS  Google Scholar 

  29. Starzl TE, Hakala TR, Rosenthal JT, Iwatsuki S, Shaw BW Jr: Variable convalescence and therapy after cadaveric renal transplantations under cyclosporin A and steroids. Surg Gynecol Obstet 154:819–825, 1982.

    PubMed  CAS  Google Scholar 

  30. Shumway NE: Recent advances in cardiac transplantation. Transplant Proc 15:1221–1224, 1983.

    Google Scholar 

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Authors
  1. S. Iwatsuki
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  2. T. E. Starzl
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  3. B. W. Shaw Jr.
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  4. J. C. Gartner
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  5. B. E. Zitelli
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  6. J. J. Malatack
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Editor information

Editors and Affiliations

  1. Division of Hepatology, University Hospital Groningen, Groningen, The Netherlands

    Chris H. Gips

  2. Liver Transplantation Unit, Mayo Clinic, Rochester, Minnesota, 55905, USA

    Ruud A. F. Krom

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© 1985 Springer Science+Business Media Dordrecht

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Iwatsuki, S., Starzl, T.E., Shaw, B.W., Gartner, J.C., Zitelli, B.E., Malatack, J.J. (1985). Pediatric liver transplantation. In: Gips, C.H., Krom, R.A.F. (eds) Progress in Liver Transplantation. Developments in Gastroenterology, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5018-4_20

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  • DOI: https://doi.org/10.1007/978-94-009-5018-4_20

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8722-3

  • Online ISBN: 978-94-009-5018-4

  • eBook Packages: Springer Book Archive

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