Abstract
A blue cone monochromat identified by psychophysical methods was studied by electroretinography (ERG), using spectrally selective stimuli, i.e. blue, green and yellow full-field test lights on full-field backgrounds. In the absence of a background the scotopically most effective stimulus (green) produced the largest ERG and scotopically-matched stimuli (blue = green = yellow) produced univariant responses; only the strongest blue stimulus produced a slight break in univariance It was therefore presumed that these ERGs were mediated almost exclusively by rods. With a 69 cd/m2 yellow adapting field the ERGs to rod-matched yellow and green stimuli remained univariant but those to blue were not, being significantly quicker in time course. With a 103 cd/m2 white adapting field, no responses could be detected with green and yellow stimuli but only the quick response to blue light remained. It was concluded that this was the blue cone ERG. It had both an a- and b-wave, the latter being much larger (5 microvolts). At mesopic levels (yellow background) the early ‘blue’ cone ERG produced by blue light was not followed by the slower rod response known to be elicited by this blue stimulus (seen in the response to longer wave scotopically-matched stimuli), implying that the earlier blue cone response weakens or suppresses the later rod response.
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References
Alpern, M., Lee, G. B., Maaseidvaag, F. and Miller, S. S. Colour vision in blue cone ‘monochromacy’. J. Physiol. 212: 211–233 (1971).
Arden, G. B. and Frumkes, T. E. Stimulation of rods can increase cone flicker ERGs in man. Vision Res. 26: 711–721 (1986).
Blackwell, H. R. and Blackwell, O. M. Rod and cone receptor mechanisms in typical and atypical congenital achromatopsia. Vision Res. 1: 62–107 (1961).
Daw, N. W. and Enoch, J. M. Contrast sensitivity, Westheimer function and Stiles-Crawford effect in blue-cone monochromat. Vision Res. 13: 1669–1680 (1973).
Dodt, E. and Elenius, V. Change of threshold during dusk adaptation measured with orange and blue light in cats and rabbits. Experientia 16: 313–317 (1960).
Fleischman, J. A. and O’Donnell, F. E. Jr., Congenital X-linked incomplete achromatopsia. Arch. Ophthalmol. 99: 468–472 (1981).
François, J., Verriest, G., Matton-van Leuven, M. T., de Rouck, A. and Manavian, D. Atypical achromatopsia of sex-linked recessive inheritance. Am. J. Ophthalmol. 61: 1101–1108 (1966).
Gouras, P., Eggers, H. M. and MacKay, C. J. Cone dystrophy, nyctalopia and supernormal rod responses, a new retinal degeneration. Arch. Ophthalmol. 101: 718–724 (1983).
Hood, D. Suppression of the frog’s cone system in the dark. Vision Res. 23: 889–908 (1972).
Jaeger, W. Genetics of congenital colour deficiencies. In: Handbook of Sensory Physiology, Vol. VII/v: 625–642, Visual Psychophysics, D. Jameson and L. M. Hurvich (eds.). Springer-Verlag, Berlin (1972).
Sandberg, M. A., Berson, E. L. and Effron, M. H. Rod-cone interaction in the distal human retina. Science 212: 829–831 (1981).
Smith, V. C, Pokorny, J., Delleman, J. W., Cozijnsen, M., Houtman, W. A. and Went, L. N. X-linked incomplete achromatopsia with more than one class of functional cones. Invest. Ophthal. Vis. Sci. 24: 451–457 (1983).
Spivey, B. E., Pearlman, J. T. and Burian, H. M. Electroretinographic findings (including flicker) in carriers of congenital X-linked achromatopsia. Doc. Ophthalmol. 18: 367–375 (1964).
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© 1989 Kluwer Academic Publishers, Dordrecht
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Gouras, P., Mackay, C.J., Lewis, A.L. (1989). The Blue Cone Electroretinogram Isolated in a Sex-Linked Achromat. In: Drum, B., Verriest, G. (eds) Colour Vision Deficiencies IX. Documenta Ophthalmologica Proceedings Series, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2695-0_8
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DOI: https://doi.org/10.1007/978-94-009-2695-0_8
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