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Hyperlipidaemia and Atherosclerosis in Chronic Dialysis Patients

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Replacement of Renal Function by Dialysis

Abstract

The association between hyperlipidaemia and kidney disease was first noted in 1827 by Bright who described lactescent serum in patients with the nephrotic syndrome. The advent of dialysis and renal transplantation has allowed more detailed study of lipoprotein metabolism in chronic renal failure and accumulating evidence of accelerated atherosclerosis in these patients has renewed interest in uraemic hyperlipidaemia. This chapter will document the lipid and lipoprotein abnormalities observed in dialysis patients, will outline the possible mechanisms involved in their aetiology and will discuss how such abnormalities may represent risk factors in the pathogenesis of atherosclerosis.

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Authors
  1. David C. Wheeler
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  2. Paul Sweny
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  3. Zachariah Varghese
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  4. John F. Moorhead
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Editors and Affiliations

  1. Nephrology Division, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

    John F. Maher M.D., FACP (Professor of Medicine, Director) (Professor of Medicine, Director)

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© 1989 Kluwer Academic Publishers

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Wheeler, D.C., Sweny, P., Varghese, Z., Moorhead, J.F. (1989). Hyperlipidaemia and Atherosclerosis in Chronic Dialysis Patients. In: Maher, J.F. (eds) Replacement of Renal Function by Dialysis. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1087-4_36

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  • DOI: https://doi.org/10.1007/978-94-009-1087-4_36

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6979-3

  • Online ISBN: 978-94-009-1087-4

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