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Venomous Marine Fish: Osteichthyes (Bony Fish)

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Marine and Freshwater Toxins

Part of the book series: Toxinology ((TOXI))

Abstract

The authors discuss the presence of the toxins and envenomations caused by marine bony fish, a very common cause of injuries in fishermen and bathers. The most important families of marine venomous fish are commented, and the biochemical characteristics of the venoms and clinical/therapeutical aspects of the envenomations are cited. The authors emphasize their studies on toadfish, scorpionfish, and marine catfish, the fish most frequently associated with human injuries.

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References

  • Boletini-Santos D, Komegae EN, Figueiredo SG, Haddad Jr V, Lopes-Ferreira M, Lima C. Systemic response induced by Scorpaena plumieri fish venom initiates acute lung injury in mice. Toxicon. 2008;51(4):585–96.

    Article  CAS  PubMed  Google Scholar 

  • Cameron AM, Endean R. Epidermal secretion and the evolution of venom glands in fishes. Toxicon. 1973;11:401–10.

    Article  CAS  PubMed  Google Scholar 

  • Cardoso JLC, França FOS, Wen FH, Malaque CMS, Haddad Jr V. Animais peçonhentos no Brasil. Editora Sarvier: São Paulo; 2009.

    Google Scholar 

  • Faco PE, Havt A, Barbosa PS, Nobre AC, Bezerra GP, et al. Effects of Thalassophryne nattereri fish venom in isolated perfused rat kidney. Toxicon. 2003;42:509–14.

    Article  CAS  PubMed  Google Scholar 

  • Figueiredo JL, Menezes NA. Manual de Peixes Marinhos do Brasil – II. Teleostei (1). São Paulo: Universidade de São Paulo; 1978.

    Google Scholar 

  • Fonseca LA, Lopes-Ferreira M. Clinical and experimental studies regarding poisoning caused by a fish Thalassophryne nattereri (niquim). An Bras Dermatol. 2000;75:435–43.

    Google Scholar 

  • Grund LZ, Souza VM, Faquim-Mauro EL, Lima C, Lopes-Ferreira M. Experimental immunization with Thalassophryne nattereri fish venom: striking IL-5 production and impaired of B220+ cells. Toxicon. 2006;48(5):499–508.

    Article  PubMed  Google Scholar 

  • Grund LZ, Komegae EN, Lopes-Ferreira M, Lima C. IL-5 and IL-17A are critical for the chronic IgE response and differentiation of long-lived antibody-secreting cells in inflamed tissues. Cytokine. 2012;59(2):335–51.

    Article  CAS  PubMed  Google Scholar 

  • Grund LZ, Lopes-Ferreira M, Lima C. The hierarchical process of differentiation of long-lived antibody-secreting cells is dependent on integrated signals derived from antigen and IL-17A. PLoS One. 2013;8(9):e74566.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Haddad Jr V. Animais Aquáticos Potencialmente Perigosos do Brasil: guiamédico e biológico (Potentially Dangerous Aquatic Animals of Brazil: a medical and biological guide). São Paulo: Editora Roca; 2008.

    Google Scholar 

  • Haddad Jr V, Lastória JC. Envenenamento causado por um peixe-escorpião (Scorpaena plumieri Bloch, 1789) em um pescador: descrição de um caso e revisão sobre o tema. Clínica e Terapêutica. 2004;9(1):16–8.

    Google Scholar 

  • Haddad Jr V, Martins IA. Frequency and gravity of human envenomations caused by marine catfish (suborder Siluroidei): a clinical and epidemiological study. Toxicon. 2006;47:838–43.

    Article  CAS  PubMed  Google Scholar 

  • Haddad Jr V, Martins IA, Makyama HM. Injuries caused by scorpionfishes (Scorpaena plumieri Bloch, 1789 and Scorpaena brasiliensis Cuvier, 1829) in the Southwestern Atlantic Ocean (Brazilian coast): epidemiologic, clinic and therapeutic aspects of 23 stings in humans. Toxicon. 2003a;42:79–83.

    Article  CAS  PubMed  Google Scholar 

  • Haddad Jr V, Pardal PP, Cardoso JLC, Martins IA. The venomous toadfish Thalassophryne nattereri (niquim or miquim): report of 43 injuries provoked in fishermen of Salinopolis (Para State) and Aracaju (Sergipe State), Brazil. Rev Inst Med Trop Sao Paulo. 2003b;45:221–3.

    Article  Google Scholar 

  • Haddad Jr V, Souza RA, Auerbach P. Marine catfish sting causing fatal heart perforation in a fisherman. Wilderness Environ Med. 2008;19:114–8.

    Article  PubMed  Google Scholar 

  • Haddad Jr V, Lupi O, Lonza JP, Tyring SK. Tropical dermatology: marine and aquatic dermatology. J Am Acad Dermatol. 2009;61(5):733–50.

    Article  PubMed  Google Scholar 

  • Halstead BW. Poisonous and venomous marine animals of the world, Vertebrates, vol. 3. Washington, DC: US Government Print; 1970.

    Google Scholar 

  • Ishizuka EK, Ferreira MJ, Grund LZ, Coutinho EM, Komegae EN, Cassado AA, Bortoluci KR, Lopes-Ferreira M, Lima C. Role of interplay between IL-4 and IFN-γ in the in regulating M1 macrophage polarization induced by Nattectin. Int Immunopharmacol. 2012;14(4):513–22.

    Article  CAS  PubMed  Google Scholar 

  • Junqueira ME, Grund LZ, OriiNM STC, Magalhães Lopes CA, Lima C, Lopes-Ferreira M. Analysis of the inflammatory reaction induced by the catfish (Cathorops spixii) venoms. Toxicon. 2007;49(7):909–19.

    Article  CAS  PubMed  Google Scholar 

  • Komegae EN, Ramos AD, Oliveira AK, Serrano SM, Lopes-Ferreira M, Lima C. Insights into the local pathogenesis induced by fish toxins: role of natterins and nattectin in the disruption of cell-cell and cell-extracellular matrix interactions and modulation of cell migration. Toxicon. 2011;58(6–7):509–17.

    Article  CAS  PubMed  Google Scholar 

  • Komegae EN, Grund LZ, Lopes-Ferreira M, Lima C. TLR2, TLR4 and the MyD88 signaling are crucial for the in vivo generation and the longevity of long-lived antibody-secreting cells. PLoS One. 2013a;8(8):e71185.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Komegae EN, Grund LZ, Lopes-Ferreira M, Lima C. The longevity of Th2 humoral response induced by proteases natterins requires the participation of long-lasting innate-like B cells and plasma cells in spleen. PLoS One. 2013b;8(6):e67135.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lehmann DF, Hardy JC. Stonefish envenomation. N Engl J Med. 1993;329:510–1.

    Article  CAS  PubMed  Google Scholar 

  • Lima C, Bianca CP, Piran-Soares AA, Tanjoni I, Moura-da-Silva AM, Lopes-Ferreira M. Characterization of local inflammatory response induced by Thalassophryne nattereri fish venom in a mouse model of tissue injury. Toxicon. 2003;42(5):499–507.

    Article  CAS  PubMed  Google Scholar 

  • Lopes-Ferreira M, Barbaro KC, Cardoso DF, Moura-Da-Silva AM, MotaI I. Thalassophryne nattereri fish venom: biological and biochemical characterization and serum neutralization of its toxic activities. Toxicon. 1998;36(2):405–10.

    Article  CAS  PubMed  Google Scholar 

  • Lopes-Ferreira M, Moura-da-Silva AM, Mota I, Takehara HA. Neutralization of Thalassophryne nattereri (niquim) fish venom by an experimental antivenom. Toxicon. 2000;38(8):1149–56.

    Article  CAS  PubMed  Google Scholar 

  • Lopes-Ferreira M, Núñez J, Rucavado A, Farsky SHP, Lomonte B, et al. Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice. Int J Exp Pathol. 2001;82:55–64.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lopes-Ferreira M, Moura-da-Silva AM, Piran-Soares AA, Ângulo Y, Lomonte B, Gutiérrez JM, Farsky SH. Hemostatic effects induced by Thalassophryne nattereri fish venom: a model of endothelium-mediated blood flow impairment. Toxicon. 2002;40(8):1141–7.

    Article  CAS  PubMed  Google Scholar 

  • Lopes-Ferreira M, Emim JÁ, Oliveira V, Puzer L, Cezari M, Het AL. Kininogenase activity of Thalassophryne nattereri fish venom. Biochem Pharmacol. 2004;68(11):2151–7.

    Article  CAS  PubMed  Google Scholar 

  • Lopes-Ferreira M, Magalhães GS, Fernandez JH, Junqueira-de-Azevedo IL, Lee Ho P, Lima C, et al. Structural and biological characterization of Nattectin, a new C-type lectin from the venomous fish Thalassophryne nattereri. Biochimie. 2011;93(6):971–80.

    Article  CAS  PubMed  Google Scholar 

  • Magalhães GS, Lopes-Ferreira M, Junqueira-de-Azevedo IL, Spencer PJ, Araújo MS, Portaro FC, et al. Natterins, a new class of proteins with kininogenase activity characterized from Thalassophryne nattereri fish venom. Biochimie. 2005;87(8):687–99.

    Article  PubMed  Google Scholar 

  • Magalhães GS, Junqueira-de-Azevedo IL, Lopes-Ferreira M, Lorenzini DM, Ho PL, Moura-da-Silva AM. Transcriptome analysis of expressed sequence tags from the venom glands of the fish Thalassophryne nattereri. Biochimie. 2006;88(6):693–9.

    Article  PubMed  Google Scholar 

  • Menezes TN, Carnielli JB, Gomes HL, Pereira FE, Lemos EM, Bissoli NS, Lopes-Ferreira M, Andrich F, Figueiredo SG. Local inflammatory response induced by scorpionfish Scorpaena plumieri venom in mice. Toxicon. 2012;60(1):4–11.

    Article  CAS  PubMed  Google Scholar 

  • Pareja-Santos A, Saraiva TC, Costa EP, Santos MF, Zorn TT, Souza VM, Lopes-Ferreira M, Lima C. Delayed local inflammatory response induced by Thalassophryne nattereri venom is related to extracellular matrix degradation. Int J Exp Pathol. 2009;90(1):34–43.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Piran-Soares AA, Komegae EN, Souza VM, Fonseca LA, Lima C, Lopes-Ferreira M. Neutralizing antibodies obtained in a persistent immune response are effective against deleterious effects induced by the Thalassophryne nattereri fish venom. Toxicon. 2007;49(7):920–30.

    Article  CAS  PubMed  Google Scholar 

  • Quay WB. Integument and the environment: glandular composition, function, and evolution. Am Zool. 1972;12:95.

    Article  Google Scholar 

  • Ramos AD, Conceição K, Silva Jr PI, Richardson M, Lima C, Lopes-Ferreira M. Specialization of the sting venom and skin mucus of Cathorops spixii reveals functional diversification of the toxins. Toxicon. 2012;59(6):651–65.

    Article  CAS  PubMed  Google Scholar 

  • Saraiva TC, Grund LZ, Komegae EN, Ramos AD, Conceição K, Orii NM, Lopes-Ferreira M, Lima C. Nattectin a fish C-type lectin drives Th1 responses in vivo: licenses macrophages to differentiate into cells exhibiting typical DC function. Int Immunopharmacol. 2011;11(10):1546–56.

    Article  CAS  PubMed  Google Scholar 

  • Skeie E. Toxin of the Weeverfish (Trachinus Draco) Experimental Studies on Animals. Acta Pharmacologica et Toxicologica 1962;19(2):107–120

    Google Scholar 

  • Wiener S. Observations on the venom of the stonefish (Synanceja trachynis). Med J Aust. 1959;46:620–7.

    CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Botucatu Medicine School, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

    Vidal Haddad Jr.

  2. Centre for Applied Toxinology, Butantan Institute, Av Vital Brazil, 1500, Butantã, 05503-900, São Paulo, SP, Brazil

    Carla Lima & Mônica Lopes-Ferreira

Authors
  1. Vidal Haddad Jr.
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  2. Carla Lima
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  3. Mônica Lopes-Ferreira
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Corresponding author

Correspondence to Vidal Haddad Jr. .

Editor information

Editors and Affiliations

  1. Dept of Anatomy, Natl Univ of Singapore, Singapore, Singapore

    P. Gopalakrishnakone

  2. Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

    Vidal Haddad Jr.

  3. Department of Life Sciences, University of Trieste, Trieste, Italy

    Aurelia Tubaro

  4. College of Veterinary Medicine, Gyeongsang National University, Jinju, Korea (Republic of)

    Euikyung Kim

  5. College of Medicine, University of Florida, Gainesville, Florida, USA

    William R. Kem

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© 2016 Springer Science+Business Media Dordrecht

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Haddad, V., Lima, C., Lopes-Ferreira, M. (2016). Venomous Marine Fish: Osteichthyes (Bony Fish). In: Gopalakrishnakone, P., Haddad Jr., V., Tubaro, A., Kim, E., Kem, W. (eds) Marine and Freshwater Toxins. Toxinology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6419-4_10

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