Abstract
Leakage current is a critical factor which can balance ions flow across channels in neuron. In this study, a simple case is considered about the influence of leakage conductance gL on neuronal firing activities in a two compartment model, the detailed analysis includes two aspects: (1). the values of gL in the two compartments are equal, (2). the values of gL in the two compartments are not equal. With computer simulation, it is found that numerical results obtained from the variation of gL in somatic compartment and dendritic compartment show much difference, simulation results obtained from variation of gL in dendritic compartment have much similarity with results got in case (1) when gL varies, while the variation of gL in soma gives some difference with the case in (1). In the final the changing of membrane capacitance to the potential spike is also discussed here. All these results may give us a general rule of neuronal firing properties.
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Acknowledgments
This work is supported by the National Nature Science Foundation of China under Grant Nos. 10872069.
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Wang, L., Liu, S. (2013). The Effects of Leakage Conductance on Firing Properties in a Compartment Neuron Model. In: Yamaguchi, Y. (eds) Advances in Cognitive Neurodynamics (III). Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4792-0_108
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DOI: https://doi.org/10.1007/978-94-007-4792-0_108
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