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Meta-Analysis of Qualitative Diagnostic Tests

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Statistics Applied to Clinical Studies

Abstract

In the past few years many novel diagnostic methods have been developed, including multi-slice computer tomography, magnetic resonance, positive emission tomography and many more methods. Studies evaluating their respective sensitivities and specificities have been published, and meta-analyses of these studies can now be performed in order to establish whether the findings are consistent and can be generalized across populations and morbidity/treatment variations. Sensitivity and specificity are estimators of accuracy of diagnostic methods as explained in the underneath diagram.

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Cleophas, T.J., Zwinderman, A.H. (2012). Meta-Analysis of Qualitative Diagnostic Tests. In: Statistics Applied to Clinical Studies. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2863-9_48

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