Abstract
Drugs of abuse can impinge upon an individual’s brain function and produce myriad neurobiological consequences. Drugs of abuse can produce neurobiological complications during acute intoxication, after withdrawal, and/or as a consequence of long-term abuse/dependency. Whether a direct or indirect consequence, substance abuse can induce severe negative neurobiological complications acutely or chronically. Cellular pathologies may include microglial activation, neuronal cell loss, gliosis, and axonal damage.
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Bough, K.J., Gyaw, S., Khalsa, J.H. (2015). Neurobiological Complications of Substance Abuse. In: el-Guebaly, N., Carrà, G., Galanter, M. (eds) Textbook of Addiction Treatment: International Perspectives. Springer, Milano. https://doi.org/10.1007/978-88-470-5322-9_81
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DOI: https://doi.org/10.1007/978-88-470-5322-9_81
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