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Carcinogenesis

  • Chapter
Multiple Primary Malignancies

Part of the book series: Updates in Surgery ((UPDATESSURG))

Abstract

Carcinogenesis is the process that determines the evolution of cancer and it is triggered from mutations in the DNA of normal cells. The resulting alteration in the equilibrium between proliferation and programmed cell death leads to uncontrolled cell division and, therefore, tumor formation. Before the arrival of biomolecular techniques, which revealed that cancer is a pathology with genetic origins, there were various hypotheses regarding the etiology of this complex disease.

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Authors and Affiliations

  1. Surgical, Anesthesiology-rianimative and Emergency Sciences Department, Federico II University, Naples, Italy

    Nicola Carlomagno, Gennaro Rizzo, Cristiano Cremone, Paola Izzo & Andrea Renda

  2. Department of Biochemistry and Biomedical Technologies, Federico II University, Naples, Italy

    Francesca Duraturo

Authors
  1. Nicola Carlomagno
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  2. Francesca Duraturo
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  3. Gennaro Rizzo
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  4. Cristiano Cremone
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  5. Paola Izzo
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  6. Andrea Renda
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© 2009 Springer-Verlag Italia

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Carlomagno, N., Duraturo, F., Rizzo, G., Cremone, C., Izzo, P., Renda, A. (2009). Carcinogenesis. In: Multiple Primary Malignancies. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-1095-6_4

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  • DOI: https://doi.org/10.1007/978-88-470-1095-6_4

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-1094-9

  • Online ISBN: 978-88-470-1095-6

  • eBook Packages: MedicineMedicine (R0)

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