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Quality Management in the ICU: Understanding the Process and Improving the Art

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Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.

Abstract

Recently clinicians, researchers, nursing-staff, economists and experts in the field of health system governance have stressed the importance of quality improvement for clinical management optimization. The advances made toward quality improvement have been marked by the ability of the team leader to ration resources and improve work through the development of guidelines and audit control. Evidence-based medicine is a modern approach for integrating current medical knowledge into clinical practice. It states that management of patients should be based on the rigorous assessment of the results of randomized controlled trials (RCTs) combined with evidence from other forms of research. This approach has merit. Variations in the management of patients can result in care of varying quality and varying mortality [1]. Critical care physicians and nurses are involved in the quality improvementprocess in accordance with the assumptions of Davidoff and Batalden: in contrast with the primary goals of science, which are to discover and disseminate new knowledge, the primary goal of improvement is to change performance [2]. The formal version of that cycle — the Plan-Do-Study-Act model — is now a key component of medical quality improvement [3] and also includes a “Publish” step. Indeed, the biologist Edward O. Wilson has gone so far as to state that: “One of the strictures of the scientific ethos is that a discovery does not exist until it is safely reviewed and in print” [4]. Unfortunately, publication in medical quality improvement has played a limited role to date. This lack of published reports has arguably deprived the health care system of rigorous scholarly evidence on work improvement and hence has slowed the development of the improvement process [5].

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References

  1. Brochard L, Mancebo J, Tobin M (2002) Searching for evidence, don’t forget the foundations. Intensive Care Med 29:2109–2111

    Google Scholar 

  2. Davidoff F, Batalden P (2005) Toward stronger evidence on quality improvement. Draft publication guidelines: the beginning of a consensus project. Qual Saf Health Care 14:319–325

    Article  PubMed  CAS  Google Scholar 

  3. Johansen KL (2007) Value of quality improvement reporting. Clin J Am Soc Nephrol [Epub ahead of print]

    Google Scholar 

  4. Wilson EO (2001) Unity of Knowledge: the convergence of natural and human science Ann NY Acad Sci 935:12–17

    CAS  Google Scholar 

  5. Vemula R, Robyn Assaf R, Al-Assaf AF (2007) Making the Patient Safety and Quality Improvement Act of 2005 work. J Health Qual 29:6–10

    Google Scholar 

  6. Ledingham IM (2001) Evidence based medicine: physicians’ perceptions. Intensive Care Med 27:464–466

    Article  PubMed  CAS  Google Scholar 

  7. Committee on Quality of Health Care in America: Crossing the quality chasm: a new health system for the 21st century (2001) Washington, DC, National Academy Press

    Google Scholar 

  8. Pronovost PJ, Berenholtz SM, Ngo K, et al (2003) Developing and pilot testing quality indicators in the intensive care unit. J Crit Care 18:145–155

    Article  PubMed  Google Scholar 

  9. Rollins G (2007) Quality. New Joint Commission measures in the works. Hosp Health Net 81:32

    Google Scholar 

  10. Curtis JR, Cook DJ, Wall RJ, et al (2006) Intensive care unit quality improvement: a “how-to” guide for the interdisciplinary team. Crit Care Med 34:211–218

    Article  PubMed  Google Scholar 

  11. Donabedian A (1993) Continuity and change in the quest for quality. Clin Perform Qual HealthCare 1:9–16

    CAS  Google Scholar 

  12. Pronovost PJ, Angus DC, Dorman T, et al (2002) Physician staffing patterns and clinical outcomes in critically ill patients: A systematic review. JAMA 288:2151–2162

    Article  PubMed  Google Scholar 

  13. Kane RL, Shamliyan T, Mueller C et al. (2007) Nurse staffing and quality of patient care. Evid Rep Technol Assess 151:1–115

    Google Scholar 

  14. Stone PW, Mooney-Kane C, Larson EL et al (2007) Nurse working conditions and patient safety outcomes. Med Care 45:571–578

    Article  PubMed  Google Scholar 

  15. Stucke S, Menzel NN (2007) Ergonomic assessment of a critical care unit. Crit Care Nurs Clin North Am 19:155–165

    Article  PubMed  Google Scholar 

  16. Carlet J (1996) Quality assessment of intensive care units. Curr Opin Crit Care 2:319–325

    Article  Google Scholar 

  17. Kalassian KG, Dremsizov T, Angus DC (2002) Translating research evidence into clinical practice: new challenges for critical care. Crit Care 6:11–14

    Article  PubMed  Google Scholar 

  18. Garland A. (2005) Improving the ICU: Part 1. Chest 127:2151–2164

    Article  PubMed  Google Scholar 

  19. Ledoux D, Finfer S, McKinley S (2005) Impact of operator expertise on collection of the APACHE II score and on the derived risk of death and standardized mortality ratio. Anaesth Intensive Care 33:585–590

    PubMed  CAS  Google Scholar 

  20. SAPS-3. Available at: http://www.spci.org/saps3/. Accessed February 5, (2006) Chest 128:348s

    Google Scholar 

  21. Arabi Y, Al Shirawi N, Memish Z, et al. (2003) Assessment of six mortality prediction models in patients admitted with severe sepsis and septic shock to the intensive care unit: a prospective cohort study. Crit Care 7:R116–R122

    Article  PubMed  Google Scholar 

  22. Herridge MS (2003) Prognostication and intensive care unit outcome: the evolving role of scoring systems. Clin Chest Med 24:751–762

    Article  PubMed  Google Scholar 

  23. Hyzy RC (1995) ICU scoring systems and clinical decision making. Chest 107:1482–1483

    Article  PubMed  CAS  Google Scholar 

  24. Goldfrad C, Rowan K (2000) Consequences of discharges from intensive care at night. Lancet 355:1138–1142

    Article  PubMed  CAS  Google Scholar 

  25. Beck DH, Mc Quillan P, Smith GB (2002) Waiting for the break of dawn? The effects of discharge time, discharge TISS scores and discharge facility on hospital mortality after intensive care. Intensive Care Med 28:1287–1293

    Article  PubMed  Google Scholar 

  26. Marik PE, Hedman L (2000) What’s in a day? Determining intensive care unit length of stay. Crit Care Med 28:2090–2093

    Article  PubMed  CAS  Google Scholar 

  27. Daly K, Beale R, Chang RW (2001) Reduction in mortality after inappropriate early discharge from intensive care unit: logistic regression triage model. BMJ 322:1274–1276

    Article  PubMed  CAS  Google Scholar 

  28. Kalb PE, Miller DH. (1989) Utilization strategies for intensive care units. JAMA 261:2389–2395

    Article  PubMed  CAS  Google Scholar 

  29. Abbott KH, Sago JG, Breen CM et al (2001) Families looking back: one year after discussion of withdrawal or withholding of life-sustaining support. Crit Care Med 29:197–201

    Article  PubMed  CAS  Google Scholar 

  30. Williams B. (1994) Patient satisfaction: a valid concept? Soc Sci Med 38:509–516

    Article  PubMed  CAS  Google Scholar 

  31. Avis M, Bond M, Arthur A (1995) Satisfying solutions? A review of some unresolved issues in the measurement of patient satisfaction. J Adv Nurs 22:316–322

    Article  PubMed  CAS  Google Scholar 

  32. Azoulay E, Pochard F, Chevret S, et al (2001) Meeting the needs of intensive care unit patient families: a multicenter study. Am J Respir Crit Care Med 163:135–139

    PubMed  CAS  Google Scholar 

  33. Malacrida, R, Molo Bettelini, C, Degrate, A, et al. (1998) Reasons for dissatisfaction: a survey of relatives of intensive care patients who died. Crit Care Med 26, 1187–1193

    Article  PubMed  CAS  Google Scholar 

  34. Johnson D, Wilson M, Cabanaugh B et al (1998) Measuring the ability to meet family needs in an intensive care unit. Crit Care Med 26:266–271

    Article  PubMed  CAS  Google Scholar 

  35. Guyatt GH, Mitchell A, Molloy DW et al (1995) Measuring patient and relative satisfaction with level or aggressiveness of care and involvement in care decisions in the context of life threatening illness. J Clin Epidemiol 48:1215–1224

    Article  PubMed  CAS  Google Scholar 

  36. Heyland DK, Rocker FM, Dodek PM et al (2002) Family satisfaction with care in the intensive care unit: results of a multiple center study. Crit Care Med 30:1413–1418

    Article  PubMed  Google Scholar 

  37. Larson CO, Nelson EC, Gustafson D, et al (1996) The relationship between meeting patients’ information needs and their satisfaction with hospital care and general health status outcome. Int J Qual Health Care 8:447–456

    PubMed  CAS  Google Scholar 

  38. Decker PJ, Strader MK (1997) Beyond JCAHA: Using competency models to improve health care organizations. Hospital Topics 75:10–17

    Article  PubMed  CAS  Google Scholar 

  39. Moullin M (2004). Eight essentials of performance measurement. Int J Health Care Qual Assur Inc Leadersh Health Serv 17:110–112

    PubMed  Google Scholar 

  40. Garland A (2005) Improving the ICU: Part 2. Chest 127:2165–2179

    Article  PubMed  Google Scholar 

  41. Motwani J, Sower VE, Brashier LW (1996) Implementing TQM in the health care sector. Health Care Manage Rev 21:73–82

    PubMed  CAS  Google Scholar 

  42. ICU Quality Improvement: Professional Resources for Quality Improvement and Quality Corner. Society of Critical Care Medicine (2005) Available at: http://www.sccm.org

    Google Scholar 

  43. Docimo AB, Pronovost PJ, Davis RO et al (2000) Using the online and offline change model to improve efficiency for fast-track patients in an emergency department. Jt Comm J Qual Improv 26:503–514

    PubMed  CAS  Google Scholar 

  44. Cook DJ, Montori VM, McMullin JP, et al (2004) Improving patients’ safety locally: changing clinician behaviour. Lancet 363:1224–1230

    Article  PubMed  CAS  Google Scholar 

  45. Pronovost PJ, Weast B, Holzmueller CG et al (2007) Evaluation of the culture of safety: survey of clinicians and managers in an academic medical center. Qual Saf Health Care 12:405–410

    Article  Google Scholar 

  46. Dodek PM, Heyland DK, Rocker GM et al (2004) Translating family satisfaction data into quality improvement. Crit Care Med 32:1922–1927

    Article  PubMed  Google Scholar 

  47. Grimshaw JM, Shirran L, Thomas R et al (2001) Changing provider behavior: an overview of systematic reviews of interventions. Med Care 39:112–1145

    Article  Google Scholar 

  48. Cabana MD, Rand CS, Power NR et al (1999) Why don’t physicians follow clinical practice guidelines? A framework for improvement. JAMA 282:1458–1465

    Article  PubMed  CAS  Google Scholar 

  49. Thomson O’Brien MA, Oxman AD, Davis DA et al (2000) Audit and feedback: effects on professional practice and health care outcomes. Cochrane Database Syst Rev CD000259

    Google Scholar 

  50. Grol R (2001) Improving the quality of medical care: building bridges among professional pride, payer profit, and patient satisfaction. JAMA 286:2578–2585

    Article  PubMed  CAS  Google Scholar 

  51. NSW Health Department (2001) The clinician’s toolkit for improving patient care NSW Health Department, Sydney

    Google Scholar 

  52. Ronald M, Campbell S, Wilkin D (2001) Clinical governance: a convincing strategy for quality improvement? J Manag Med 15(3)188–201

    Article  Google Scholar 

  53. Scally G, Donaldson L (1998) Clinical governance and the drive for quality improvement in the NHS. BMJ 317:61–65

    PubMed  CAS  Google Scholar 

  54. Warburton RN (2005) Patients Safety how much is enough? Health policy 71:223–232

    Article  PubMed  Google Scholar 

  55. Holcolm BW, Wheeler AP, Ely EW (2001) New ways to improve unnecessary variation and improve outcomes in the intensive care unit. Curr Opin Crit Care 7:304–311

    Article  Google Scholar 

  56. Nelson EC, Batalden PB, Ryer, JC (1998) Clinical Improvement Action Guide. Oakbrook Terrace, Illinois, Joint Commission

    Google Scholar 

  57. Berwick DM (1998) Developing and testing changes in delivery of care. Ann Intern Med 128:651–656

    PubMed  CAS  Google Scholar 

  58. Angus DC, Black N (2004) Improving care of the critically ill: institutional and healthcare system approaches. The Lancet 303:1314–1320

    Article  Google Scholar 

  59. Reinertsen JL (1998) Physicians as leaders in the improvement of health care systems. Ann Intern Med. 128:833–888

    PubMed  CAS  Google Scholar 

  60. Joint Commission (1999). Pocket Guide to Using Performance Improvement Tools Oakbrook Terrace, Illinois, Joint Commission

    Google Scholar 

  61. Langley GJ, Nolan KM, Nolan TW et al (1996) The Improvement Guide: a Practical Approach to Enhancing Organizational Performance. San Francisco, Jossey-Bass

    Google Scholar 

  62. Kohn LT, Corrigan JM, Donaldson MS (2000) To err is human: building a safer health system. Washington, DC, National Academy Press

    Google Scholar 

  63. Starfield B (2000) Is US health really the best in the world? JAMA 284:483–484

    Article  PubMed  CAS  Google Scholar 

  64. Zhan C, Miller MR (2003) Excess length of stay, charges and mortality attributable to medical injuries during hospitalization. JAMA 290:1868–1874

    Article  PubMed  CAS  Google Scholar 

  65. Haywood RA, Hofer TP. (2001) Estimating hospital deaths due to medical errors. JAMA 286:415–420

    Article  Google Scholar 

  66. Safe Practices for Better Healthcare: A Consensus Report (2003) Available at: http://www.qualityforum.org/txsafeexecsumm_order6-8-03PUBLIC.pdf

    Google Scholar 

  67. Sexton JB, Thomas EJ, Helmreich RL (2000) Error, stress, and teamwork in medicine and aviation: cross sectional surveys. BMJ 320:745–749

    Article  PubMed  CAS  Google Scholar 

  68. Miller PA (2001) Nurse-physician collaboration in an intensive care unit. Am J Crit Care 10:341–350

    PubMed  CAS  Google Scholar 

  69. Baggs JG, Schmitt MH, Mushlin AI et al (1997) Nurse-physician collaboration and satisfaction with the decision-making process in three critical care units. Am J Crit Care 6:393–399

    PubMed  CAS  Google Scholar 

  70. Reader TW, Flin R, Mearns K et al. (2007) Interdisciplinary communication in the intensive care unit. Br J Anaesth 98:347–352

    Article  PubMed  CAS  Google Scholar 

  71. Ashton CM, Kuykendall DH, Johnson ML et al (1995) The association between the quality of inpatient care and early readmission. Ann Intern Med 122:415–421

    PubMed  CAS  Google Scholar 

  72. Schuster MA, McGlynn EA, Brook RH (1998) How good is the quality of health care in the United States? Milbank Q 76:517–563

    Article  PubMed  CAS  Google Scholar 

  73. McNeil BJ. (2001) Shattuck lecture: hidden barriers to improvement in the quality of care. N Engl J Med 345:1612–1620

    Article  PubMed  CAS  Google Scholar 

  74. Performance Measurement in Health Care. (2005). Joint Commission on Accreditation of Healthcare Organizations Available at: http://www.jcaho.org/pms/index.htm

    Google Scholar 

  75. VHA Health Foundation (2006) http://www.vhahealthfoundation.org/vhahf/improvingsepsiscare.asp

    Google Scholar 

  76. IHI.org. Available at: http://www.ihi.org/IHI/Topics/CriticalCare/Sepsis/Literature/SepsisCareEntersNewEra.htm. Accessed February 10, 2006

    Google Scholar 

  77. The National Quality Forum. Available at: http://www.qualityforum.org. Accessed January 12, 2006

    Google Scholar 

  78. The Leapfrog Group. Available at: http://www.leapfroggroup.org/about_us. Accessed January 12, 2006

    Google Scholar 

  79. Croley WC, Rothenberg DM (2007) Education of trainees in the intensive care unit. Crit Care Med 35(2 Suppl):S117–121

    Article  PubMed  Google Scholar 

  80. Tuttle RP, Cohen MH, Augustine AJ et al (2007) Utilizing simulation technology for competency skills assessment and a comparison of traditional methods of training to simulation-based training. Respir Care 52:263–270

    PubMed  Google Scholar 

  81. Dunn EJ, Mills PD, Neily J et al (2007) Medical team training: applying crew resource management in the Veterans Health Administration. Jt Comm J Qual Patient Saf 33:317–325

    PubMed  Google Scholar 

  82. Rashid M (2007) Developing scales to evaluate staff perception of the effects of the physical environment on patient comfort, patient safety, patient privacy, family integration with patient care, and staff working conditions in adult intensive care units: a pilot study. Crit Care Nurs Q 30:271–283

    PubMed  Google Scholar 

  83. The interface between clinical audit and management A report of working group set up by clinical resource and audit group. The Scottish Office 1993: p9

    Google Scholar 

  84. Principles for Best Practice in Clinical Audit. London: NICE (2002) www.nelh.nhs.uk/nice_bpca.asp

    Google Scholar 

  85. Lack JA, White LA, Thoms GM, Rollin AM (eds) (2000) Raising the standard: a compendium of audit recipes for continuous quality improvement in anaesthesia. London, Royal College of Anaesthetists

    Google Scholar 

  86. The NHS Clinical Governance Support Team. Practical Clinical Audit Handbook (2005) www.cgsupport.nhs.uk/resources/clinical_aud it/]

    Google Scholar 

  87. Wakabayashi H, Sano T, Yachida S, Okano K, Izuishi K, Suzuki Y. (2007) Validation of risk assessment scoring systems for an audit of elective surgery for gastrointestinal cancer in elderly patients. Int J Surg 5:323–327

    Article  PubMed  Google Scholar 

  88. Thomson O’Brien MA, Oxman AD, Davis DA et al (2000) Audit and feedback: effects on professional practice and health care outcomes (Cochrane review). In: The Cochrane Library, Issue 4, Oxford: Update Software

    Google Scholar 

  89. Thomson O’Brien MA, Oxman AD, Davis DA et al. (2000) Audit and feedback versus alternative strategies: effects on professional practice and health care outcomes (Cochrane review). In: The Cochrane Library, Issue 4. Oxford: Update Software.

    Google Scholar 

  90. Ursprung R, Gray JE, Edwards VH et al (2005) Real time patient safety audits: improving safety every day. Qual Saf Health Care 14:284–289

    Article  PubMed  CAS  Google Scholar 

  91. Sinuff T, Cook D, Giacomini M et al (2007) Facilitating clinician adherence to guidelines in the intensive care unit: a multicenter, qualitative study. Crit Care Med 35:2083–2089

    Article  PubMed  Google Scholar 

  92. Simpson P, Harmer M (2005) Audit using both the good and the bad news to improve patient care. BJA 95:121–123

    Article  PubMed  CAS  Google Scholar 

  93. Gullo A (2006) Postoperative monitoring: principles, organization and quality of care. Definition of risk, evidence-based medicine, audit and quality of care. Minerva Anestesiol 72:171–181

    PubMed  CAS  Google Scholar 

  94. Standl T (2007) Abdominal compartment syndrome: a still underestimated problem? Anasthesiol Intensivmed Notfallmed Schmerzther 42:500–503

    Article  PubMed  Google Scholar 

  95. Ball AP, Bartlett JG, Graig WA et al (2004) Future trends in antimicrobial chemotherapy: expert opinion on the 43rd ICAAC. J Chemiother 16:419–436

    CAS  Google Scholar 

  96. Bax RP, Mullan N (1999) Response of the pharmaceutical industry to antimicrobial resistance. Balliere Clin Infect Dis 5:289–304

    Google Scholar 

  97. Coates ARM, Hu Y (2007) Novel approaches for developing new antibiotics for bacterial infections. Br J Pharmacol [Epub ahead of print]

    Google Scholar 

  98. Taylor MJ, Scuffham PA, McCollam PL, Newby DE (2007) Acute coronary syndromes in Europe: 1-year costs and outcomes. Curr Med Res Opin 23:495–503

    Article  PubMed  Google Scholar 

  99. Collet JP, Montalescot G (2007) Management coronary syndrome in the acute phase. Ann Cardiol Angeiol (Paris). 56Suppl 1:S21–28

    Article  Google Scholar 

  100. Ferrières J, Cambou J (2007) Epidemiology of acute coronary syndrome in France. Ann Cardiol Angeiol (Paris). 56Suppl 1:S8–S15

    Article  Google Scholar 

  101. Alexander KP, Newby LK, Armstrong PW et al (2007) Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology. American Heart Association Council on Clinical Cardiology; Society of Geriatric Cardiology. Circulation 115:2570–2589

    Article  PubMed  Google Scholar 

  102. Van Horn SE Jr, Maniu CV. (2007). Management of non-ST-segment elevation myocardial infarction. Med Clin North Am 91:683–700

    Article  PubMed  Google Scholar 

  103. Spinler SA (2007) Managing acute coronary syndrome: evidence-based approaches. Am J Health Syst Pharm 1:64 (Suppl 7):S14–24

    Article  Google Scholar 

  104. Kapoor JR (2007) Nesiritide in acute decompensated heart failure: to use or not to use, that is the question? Am J Cardiol 15:100:745–746

    Article  Google Scholar 

  105. Dunn A, Sachak S (2007) Nesiritide and renal function after cardiac surgery. Am J Health Syst Pharm 1:64:1582–1584

    Article  Google Scholar 

  106. Zemljic G, Bunc M, Yazdanbakhsh AP, Vrtovec B (2007) Levosimendan improves renal function in patients with advanced chronic heart failure awaiting cardiac transplantation. J Card Fail 13:417–421

    Article  PubMed  CAS  Google Scholar 

  107. Iakobishvili Z, Hasdai D (2007) Cardiogenic shock treatment. Med Clin North Am (2007) 91:713–727

    Article  PubMed  CAS  Google Scholar 

  108. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. (2007) Guideline for mechanical ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease. Society of Critical Care Medicine, Chinese Medical Association 19:513–518

    Google Scholar 

  109. Harrison AM, Cox AC, Davis S et al. (2002) Failed extubation after cardiac surgery in young children: Prevalence, pathogenesis, and risk factors. Pediatr Crit Care Med. 3(2):148–152

    Article  PubMed  Google Scholar 

  110. Caroleo S, Agnello F, Abdallah K et al (2007) Weaning from mechanical ventilation: an open issue. Minerva Anestesiol 73:417–427

    PubMed  CAS  Google Scholar 

  111. Matić I, Danić D, Majerić-Kogler V et al (2007) Chronic obstructive pulmonary disease and weaning of difficult-to-wean patients from mechanical ventilation: randomized prospective study. Croat Med J 2007 48:51–58

    PubMed  Google Scholar 

  112. Wolthuis EK, Veelo DP, Choi G et al (2007) Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedatives. Crit Care 11:R77

    Article  PubMed  Google Scholar 

  113. Petrucci N, Iacovelli W (2007) Lung protective ventilation strategy for the acute respiratory distress syndrome. Cochrane Database Syst Rev (3):CD003844

    Google Scholar 

  114. Tobin MJ (2001) Advances in mechanical ventilation. N Engl J Med 344:1986–1996

    Article  PubMed  CAS  Google Scholar 

  115. The Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volume compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308

    Google Scholar 

  116. Malhotra A (2007) Low tidal volume ventilation in the acute respiratory distress Syndrome. N Engl J Med 357:1113–1120

    Article  PubMed  CAS  Google Scholar 

  117. Olasveengen TM, Wik L, Kramer-Johansen J et al (2007) Is CPR quality improving? A retrospective study of out-of-hospital cardiac arrest. Resuscitation [Epub ahead of print]

    Google Scholar 

  118. Kramer-Johansen J, Myklebust H, Wik L, (2006) Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study. Resuscitation. 71:283–292

    Article  PubMed  Google Scholar 

  119. Sahuquillo J, Vilalta A (2007) Cooling the injured brain: how does moderate hypothermia influence the pathophysiology of traumatic brain injury. Curr Pharm Des 13:2310–2322

    Article  PubMed  CAS  Google Scholar 

  120. Kaneko T, Maekawa T (2007) Clinical application of brain hypothermia therapy for acute brain insults. Masui 56:280–284

    PubMed  Google Scholar 

  121. Fukuda S, Warner DS (2007) Cerebral protection. Br J Anaesth 99:10–17

    Article  PubMed  CAS  Google Scholar 

  122. Borgel D, Bornstain C, Reitsma PH et al (2007) Comparative study of the protein C pathway in septic and non-septic patients with organ failure. Am J Respir Crit Care Med [Epub ahead of print]

    Google Scholar 

  123. Kuang D, Verbine A, Ronco C (2007) Pharmacokinetics and antimicrobial dosing adjustment in critically ill patients during continuous renal replacement therapy. Clin Nephrol 67:267–284

    PubMed  CAS  Google Scholar 

  124. Van den Berghe G, Wilmer A, Hermans G et al (2006) Intensive insulin therapy in the medical ICU. N Engl J Med 354:5:449–461

    Article  PubMed  Google Scholar 

  125. McCowen KC, Malhotra A, Bistrian BR (2001) Endocrine and metabolic dysfunction syndromes in the critically ill. Crit Care Clin 17:107–124

    Article  PubMed  CAS  Google Scholar 

  126. Van den Berghe G, Wouters P, Weekers F et al (2001) Intensive insulin therapy in critically ill patients. N Engl J Med 345:1359–1367

    Article  PubMed  Google Scholar 

  127. Vanhorebeek I, Langouche L, Van den Berghe G (2006) Glycemic and nonglycemic effects of insulin: how do they contribute to a better outcome of critical illness? Curr Opin Crit Care 11:304–311

    Article  Google Scholar 

  128. Van den Berghe G, Wouters PJ, Bouilllon R et al (2003) Outcome benefit of intensive insulin therapy in critically ill: insulin dose versus glycemic control. Crit Care Med 31:359–366

    Article  PubMed  CAS  Google Scholar 

  129. Langouche L, Van den Berghe G (2006) Glucose metabolism and insulin therapy. Crit Care Clin 22:119–129

    Article  PubMed  CAS  Google Scholar 

  130. Malhotra A (2006) Intensive insulin in intensive care. N Engl J Med 354:16–17

    Article  Google Scholar 

  131. Angus DC, Abraham E (2005) Intensive insulin therapy in critical illness (Editorial). Am J Resp Crit Care Med 172:1358–1359

    Article  PubMed  Google Scholar 

  132. Langouche L, Vander Perre S, Wouters PJ et al (2007) Effect of intensive insulin therapy on insulin sensitivity in the critically ill. J Clin Endocrinol Metab 92:3890–3897

    Article  PubMed  CAS  Google Scholar 

  133. Lemiengre J, de Casterle BD, Van Craen K et al (2007) Institutional ethics policies on medical end-of-life decisions: a literature review. Health Policy 83:131–143

    Article  PubMed  Google Scholar 

  134. Virnig B (2007) Institutional care at the end of life. Med Care 45:916–917

    Article  PubMed  Google Scholar 

  135. Bellini C, Petignat C, Francioli P et al (2007) Comparison of automated strategies for surveillance of nosocomial bacteremia. Infect Control Hosp Epidemiol 28:1030–1035

    Article  PubMed  Google Scholar 

  136. Gastmeier P (2007) Evidence-based infection control in the ICU (except catheters). Curr Opin Crit Care 13:557–562

    Article  PubMed  Google Scholar 

  137. Etchells E, Sharpe G, Walsh P et al (1996) Bioethics for clinicians: 1. Consent. CMAJ 155:177–180

    PubMed  CAS  Google Scholar 

  138. Levine RJ (1991) Informed consent: some challenges to universal validity of the Western model. Law Med Health Care 19:207–213

    PubMed  CAS  Google Scholar 

  139. Blackhall LJ, Murph ST, Frank G et al (1995) Ethnicity and attitudes toward patient autonomy. JAMA 274:820–825

    Article  PubMed  CAS  Google Scholar 

  140. Azoulay E, Chevret S, Leleu G et al (2000) Half of the family of intensive care unit patients experience inadequate communications with physicians. Crit Care Med 28:3044–3049

    Article  PubMed  CAS  Google Scholar 

  141. Ely EW, Margolin R, Francis J et al (2001) Evaluation of delirium in critically ill patients: validation of the confusion assessment method for the intensive care unit (CAM-ICU). Crit Care Med 29:1370–1379

    Article  PubMed  CAS  Google Scholar 

  142. Dyson M (1999) Intensive care unit psychosis, the therapeutic nursing-patients relationship and the influence of the intensive care setting: analyses of interrelating factors. JAMA 286:2703–2710

    Google Scholar 

  143. Sulmasy DP, Haller K, Terry PB (1994) More talk, less paper: predicting the accuracy of substituted judgments. Am J Med 96:432–438

    Article  PubMed  CAS  Google Scholar 

  144. Davis N, Pohlman A, Gehalback B et al (2003) Improving the process of informed consent in the critically ill. JAMA 289:1963–1968

    Article  PubMed  Google Scholar 

  145. Clark PA (2007) Intensive care patients’ evaluations of the informed consent process. Dimens Crit Care Nurs 26:207–226

    Article  PubMed  Google Scholar 

  146. Salzman JG, Frascone RJ, Godding BK (2007) Implementing emergency research requiring exception from informed consent, community consultation, and public disclosure. Ann Emerg Med 50:448–455, 455.e1-4

    Article  PubMed  Google Scholar 

  147. Sakka SG (2007) Assessing liver function. Curr Opin Crit Care 13:207–214

    Article  PubMed  Google Scholar 

  148. Stadibauer V, Jalan R. Liver Failure Group (2007) Acute liver failure: liver support therapies. Curr Opin Crit Care 13:215–221

    Article  Google Scholar 

  149. O’Grady J (2007) Modern management of acute liver failure. Clin Liver Dis 11:291–303

    Article  PubMed  Google Scholar 

  150. Powell-Tuck J (2007) Nutritional interventions in critical illness. Proc Nutr Soc 66:16–24

    Article  PubMed  CAS  Google Scholar 

  151. Jefic D, Lee JW, Jefic D et al (2005) Utility of â-natriuretic peptide and N-terminal pro β-type natriuretic peptide in evaluation of respiratory failure in critically ill patients. Chest 128:288–295

    Article  PubMed  CAS  Google Scholar 

  152. Povoa P, Coelho, Almeida E et al (2005) C-reactive protein as of infection in critically ill patient. Clin Microbiol Infect 11:101–108

    Article  PubMed  CAS  Google Scholar 

  153. Povoa P, Coelho, Almeida E et al (2005) C-reactive protein as a marker of ventilâtor-associated pneumonia resolution: a pilot study. Eur Resp J 25:804–812

    Article  CAS  Google Scholar 

  154. Luyt CE, Guerin V, Combes A et al (2005) Procalcitonin kinetics as a prognostic marker of ventilator-associated pneumonia. Am J Respir Crit Care Med 171:48–53

    Article  PubMed  Google Scholar 

  155. Miller B (2005) Procalcitonin and ventilator associated pneumonia: yet another breath of fresh air. Am J Respr Crit Care Med 171:2–3

    Article  Google Scholar 

  156. Ye SQ, Simon BA, Maloney JP et al (2005) Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. Am J Respir Crit Care Med 171:361–370

    Article  PubMed  Google Scholar 

  157. Mishra J, Dent C, Tarabishi R et al (2005) Neutrophil gelatinase-asociated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365:1231–1238

    Article  PubMed  CAS  Google Scholar 

  158. Ngiam N, Post M, Kavanagh BP (2007) Early growth response factor-1 (EGR1) in acute lung injury. Am J Physiol Lung Cell Mol Physiol [Epub ahead of print]

    Google Scholar 

  159. Hall MW, Gavrilin MA, Knatz NL et al (2007) Monocyte mRNA phenotype and adverse outcomes from pediatric multiple organ dysfunction syndrome. Pediatr Res [Epub ahead of print]

    Google Scholar 

  160. Rincon F, Mayer SA (2007) Neurocritical care: a distinct discipline? Curr Opin Crit Care 13:115–121

    Article  PubMed  Google Scholar 

  161. Wright WL (2007) Multimodal monitoring in the ICU: when could it be useful? J Neurol Sci 261:10–15

    Article  PubMed  Google Scholar 

  162. Eid NH (2003) Human resources management nursing workload management system. http://www.moh.gov.om/nursing

    Google Scholar 

  163. Gonçalves LA, Padilha KG, Cardoso Sousa RM (2007) Nursing activities score (NAS): a proposal for practical application in intensive care units. Intensive Crit Care Nurs [Epub ahead of print]

    Google Scholar 

  164. Bouhemad B, Zhang M, Lu Q, Rouby JJ (2007) Clinical review: bedside lung ultrasound in critical care practice. Crit Care 11:205

    Article  PubMed  Google Scholar 

  165. Breitkreutz R, Walcher F, Seeger FH (2007) Focused echocardiographic evaluation in resuscitation management: concept of an advanced life support-conformed algorithm. Crit Care Med 35(Suppl):S150–161

    Article  PubMed  Google Scholar 

  166. Mathis G (2006) Ultrasound in pulmonary embolism: killing three birds with one stone. Pneumologie. 60:600–606

    Article  PubMed  CAS  Google Scholar 

  167. Wang HP, Chen SC (2007) Upper abdominal ultrasound in the critically ill. Crit Care Med 35(Suppl):S208–215

    Article  PubMed  Google Scholar 

  168. Murray CJ, Lopez A. (1996) The global burden of disease: comprehensive assessment of mortality and disability from diseases, Injuries and risk factors in 1990 and projected to 2020. Cambridge Harvard University press

    Google Scholar 

  169. National Academy of Sciences/National Research Council, Division of Medical Sciences (1996) Accidental death and disability: the neglected disease of modern society. Washington DC, NAS/NRC

    Google Scholar 

  170. Erlam R (1993) Trauma Centres. British J Surg 80:1227–1228

    Article  Google Scholar 

  171. American College of Surgeons Committee on Trauma (1983) Hospital and pre-hospital resources for optimal care of the injured patients. Bull Am Coll Surg 68:11–18

    Google Scholar 

  172. National Research Council. (1987) Confronting natural disasters: an international decade for natural disaster reduction. Washington DC, Academy press

    Google Scholar 

  173. Office of US Foreign Disaster Assistance (1994) Disaster history: significant data and major disease worldwide, 1990. Present. Washington DC, Agency for International Development

    Google Scholar 

  174. Nathens AB, Brunet FP, Maier RV (2004) Development of trauma systems and effect on outcomes after injury. Lancet 363:1794–1801

    Article  PubMed  Google Scholar 

  175. Rusnak M, Janciak I, Majdan M. Austrian Severe TBI Study Investigators (2007) Severe traumatic brain injury in Austria VI: effects of guideline-based management. INRO (International Neurotrauma Research Organisation), Vienna, Austria Wien Klin Wochenschr. 119:64–71

    Google Scholar 

  176. Lescot T, Abdennour L, Degos V (2007) Management of severe traumatic brain injury. Presse Med 36:1117–1126

    Article  PubMed  Google Scholar 

  177. Graat ME, Choi G, Wolthuis EK et al (2006) The clinical value of daily routine chest radiographs in a mixed medical-surgical intensive care unit is low. Crit Care 10:R11

    Article  PubMed  Google Scholar 

  178. Graat ME, Stoker J, Vroom MB, Schultz MJ (2005) Can we abandon daily routine chest radiography in intensive care patients? J Intensive Care Med 20:238–246

    Article  PubMed  Google Scholar 

  179. Graat ME, Hendrikse KA, Spronk PE (2006) Chest radiography practice in critically ill patients: a postal survey in the Netherlands. BMC Med Imaging 6:8

    Article  PubMed  Google Scholar 

  180. Müller-Forell W, Engelhard K (2007) Neuroimaging for the anesthesiologist. Anesthesiol Clin 25:413–439

    Article  PubMed  Google Scholar 

  181. Jones DA, McIntyre T, Baldwin I (2007) The medical emergency team and end-of-life care: a pilot study. Crit Care Resusc 9:151–156

    PubMed  Google Scholar 

  182. Dasta JF, Fuhrman TM, McCandles C (1995) Use of sedative and analgesics in a surgical intensive care unit. A follow-up and commentary. Heart Lung 2476–2478

    Google Scholar 

  183. Bair N, Bobek MB, Hoffman-Hogg L et al (2000) Introduction of sedative, analgesic, and neuromuscular blocking agent guidelines in a medical intensive care unit: physician and nurse adherence. Crit Care Med 28:707–713

    Article  PubMed  CAS  Google Scholar 

  184. Berger JT, Rosner F (1996) The ethics of practice guidelines. Arch Intern Med 156:2051–2056

    Article  PubMed  CAS  Google Scholar 

  185. Payen JF, Chanques G, Mantz J (2007) Current practices in sedation and analgesia for mechanically ventilated critically ill patients: a prospective multicenter patient-based study. Anesthesiology. 106:687–695

    Article  PubMed  Google Scholar 

  186. Park G, Lane M, Rogers S, Bassett P (2007) A comparison of hypnotic and analgesic based sedation in a general intensive care unit. Br J Anaesth 98:76–82

    Article  PubMed  CAS  Google Scholar 

  187. Nguyen HB, Smith D (2007) Sepsis in the 21st century: recent definitions and therapeutic advances. Am J Emerg Med 25:564–571

    Article  PubMed  Google Scholar 

  188. Cinel I, Dellinger RP (2007) Advances in pathogenesis and management of sepsis. Curr Opin Infect Dis 20:345–352

    Article  PubMed  Google Scholar 

  189. Huang DT, Clermont G, Dremsizov TT, Angus DC (2007) Implementation of early goal-directed therapy for severe sepsis and septic shock: a decision analysis. Crit Care Med 35:2090–2100

    Article  PubMed  Google Scholar 

  190. Rivers EP, Kruse JA, Jacobsen G et al (2007) The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock. Crit Care Med 35:2016–2024

    Article  PubMed  Google Scholar 

  191. Nguyen HB, Corbett SW, Steele R (2007) Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality. Crit Care Med 35:1105–1112

    Article  PubMed  Google Scholar 

  192. Berenholtz SM, Pronovost PJ, Ngo K ett al (2007) Core Sepsis Measurement Team. Developing quality measures for sepsis care in the ICU. Jt Comm J Qual Patient Saf 33:559–568

    PubMed  Google Scholar 

  193. Marik PE (2007) Steroids and adrenal insufficiency. Mechanisms and clinical consequences of critical illness associated adrenal insufficiency. Curr Opin Crit Care 13:363–369

    Article  PubMed  Google Scholar 

  194. Oppert M, Schindler R, Husung C et al (2005) Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock. Crit Care Med 33:2457–2464

    Article  PubMed  CAS  Google Scholar 

  195. Siraux U, De Backer D, Yalavatti D et al (2005) Relative adrenal insufficiency in patients with septic shock, comparison of low-dose and conventional corticotropin test. Crit Care Med 33:2479–2486

    Article  PubMed  CAS  Google Scholar 

  196. Wiener J, Itokazu G, Nathan C et al (1995) A randomized, double-blind, placebo-controlled trial of selective digestive decontamination in a medical intensive care unit. Clin Infect Dis 20:861–867

    PubMed  CAS  Google Scholar 

  197. Sanchez M, Mir N, Canton R et al (1997) The effect of topical vancomycin on acquisition, carriage and infection with methicillin-resistant Staphylococcus aureus in critically ill patients. A double-blind, randomised placebo controlled study. 37th ICAAC, Toronto, Canada. Abstract J-119:310

    Google Scholar 

  198. Liberati A, D’Amico R, Pifferi S et al (2004) Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. Cochrane review. In: The Cochrane library, Issue I. John Wiley and Sons, Chichester, UK

    Google Scholar 

  199. de Jonge E, Schultz M, Spanjaard L et al (2003) Effects of selective decontamination of the digestive tract: a randomised, placebo controlled, double blind trial. Med Intens 26:52

    Google Scholar 

  200. Baines P, van Saene H (2004) Selective decontamination of the digestive tract and prevention of ventilator associated pneumonia. Ann Intern Med 141:577–578

    PubMed  Google Scholar 

  201. Brun-Buisson C, Legrand P, Rauss A et al (1989) Intestinal decontamination reduces nosocomial infections and length of stay but not mortality or organ failure in surgical intensive care unit patients. Arch Surg 127:163–169

    Google Scholar 

  202. Arnow P, Caradang GC, Zabner R, Irvin ME (1996) Randomized controlled trial of selective digestive decontamination for prevention of infections following liver transplantation. Clin Infect Dis 22:997–1003

    PubMed  CAS  Google Scholar 

  203. Stoutenbeek CP, van Saene HKF, Zandstra DF (1987) The effect of oral non-absorbable antibiotics on the emergence of resistant bacteria in patients in an intensive care unit. J Antimicrob Chemother 19:513–520

    Article  PubMed  CAS  Google Scholar 

  204. Silvestri L, Milanese M, Oblach L et al (2002) Enteral vancomycin to control methicillin-resistant Staphylococcus aureus outbreak in mechanically ventilated patients. Am J Infect Control 30:391–399

    Article  PubMed  Google Scholar 

  205. Stoutenbeek CP, Van Saene HK, Miranda DR, Zandstra DF (1983) A new technique of infection prevention in the intensive care unit by selective decontamination of the digestive tract. Acta Anaesthesiol Belg 34:209–221

    PubMed  CAS  Google Scholar 

  206. Stoutenbeek CP, van Saene HKF, Miranda DR, Zandstra DF (1984) The effect of selective decontamination of the digestive tract on colonization and infection rate in multiple trauma patients. Intensive Care Med 10:185–192

    Article  PubMed  CAS  Google Scholar 

  207. Silvestri L, van Saene HK, Sarginson RE, Gullo A (2007) Selective decontamination of the digestive tract and ventilator-associated pneumonia: we cannot let misinformation go uncorrected. J Intensive Care Med 22:181–182

    Article  PubMed  Google Scholar 

  208. Silvestri L, van Saene HK, Gullo A, de la Cal MA (2007) Guidelines for prevention, diagnosis, and treatment of ventilator-associated pneumonia (VAP) in the trauma patient. J Trauma 62:1062–1064

    PubMed  Google Scholar 

  209. Silvestri L, van Saene HK, Milanese M et al (2007) Selective decontamination of the digestive tract reduces bacterial bloodstream infection and mortality in critically ill patients. Systematic review of randomized controlled trials. J Hosp Infect 65:187–203

    Article  PubMed  CAS  Google Scholar 

  210. Taylor N, van Saene HK, Abella A et al (2007) Selective digestive decontamination. Why don’t we apply the evidence in the clinical practice? Med Intensiva 31:136–145

    PubMed  CAS  Google Scholar 

  211. Bryan-Brown CW, Dracup K (2003) More. Am J Crit Care 12:185–187

    PubMed  Google Scholar 

  212. Batalden PB, Davidoff F (2007) What is quality improvement and how can it transform health care? Qual Saf Health Care 16:2–3

    Article  PubMed  Google Scholar 

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Murabito, P., Rubulotta, F., Gullo, A. (2008). Quality Management in the ICU: Understanding the Process and Improving the Art. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-0773-4_33

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