Abstract
Endothelial keratoplasty is the current standard of care for diseases of corneal endothelial dysfunction, having surpassed conventional penetrating keratoplasty in terms of safety, speed and predictability of visual recovery, tectonic integrity of the globe, stability of ocular surface and refractive outcomes [1–4]. As the field of endothelial keratoplasty continues to advance and evolve, the role of combined procedures to address endothelial dysfunction with coexisting cataract has been studied. Heralded as ‘the new triple procedure’, endothelial keratoplasty combined with cataract extraction offers the promise of rapid visual rehabilitation, predictable refractive outcomes, convenience and cost-effectiveness of a one-stage procedure, without the purported risks of increased postoperative complications [5–8]. The decision to proceed with the triple procedure and surgical planning can be complex and necessitates careful consideration of the patient’s visual function and requirements, underlying cause of endothelial dysfunction, the presence of any concurrent ocular disease and target refraction. Specific modifications to surgical techniques in phacoemulsification and endothelial keratoplasty are often required to further optimize visual outcomes and minimize complications.
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References
Anshu A, Price MO, Tan DT, et al. Endothelial keratoplasty: a revolution in evolution. Surv Ophthalmol. 2012;57:236–52.
Bahar I, Kaiserman I, McAllum P, et al. Comparison of posterior lamellar keratoplasty techniques to penetrating keratoplasty. Ophthalmology. 2008;115:1525–33.
Lee WB, Jacobs DS, Musch DC, et al. Descemet’s stripping endothelial keratoplasty: safety and outcomes. A report by the American Academy of Ophthalmology. Ophthalmology. 2009;116:1818–30.
Eye Bank Association of America. 2008 eye banking statistical report. Washington, DC: Eye Bank Association of America; 2009.
Terry MA, Shamie N, Chen ES, et al. Endothelial keratoplasty for Fuchs’ dystrophy with cataract: complications and clinical results with the new triple procedure. Ophthalmology. 2009;116:631–9.
Chaurasia S, Price Jr FW, Gunderson L, et al. Descemet’s membrane endothelial keratoplasty: clinical results of single versus triple procedures (combined with cataract surgery). Ophthalmology. 2014;121:454–8.
Covert DJ, Koenig SB. New triple procedure: Descemet’s stripping and automated endothelial keratoplasty combined with phacoemulsification and intraocular lens implantation. Ophthalmology. 2007;114:1272–7.
Laaser K, Bachmann BO, Horn FK, et al. Descemet membrane endothelial keratoplasty combined with phacoemulsification and intraocular lens implantation: advanced triple procedure. Am J Ophthalmol. 2012;154:47–55.
Bourne WM, Nelson LR, Hodge DO. Continued endothelial cell loss ten years after lens implantation. Ophthalmology. 1994;101:1014–22.
Hugod M, Storr-Paulsen A, Norregaard JC, et al. Corneal endothelial cell changes associated with cataract surgery in patients with type 2 diabetes mellitus. Cornea. 2011;30:749–53.
Walkow T, Anders N, Klebe S. Endothelial cell loss after phacoemulsification: relation to preoperative and intraoperative parameters. J Cataract Refract Surg. 2000;26:727–32.
Ko YC, Liu CJ, Lau LI, et al. Factors related to corneal endothelial damage after phacoemulsification in eyes with occludable angles. J Cataract Refract Surg. 2008;34:46–51.
Bourne RR, Minassian DC, Dart JK, et al. Effect of cataract surgery on the corneal endothelium: modern phacoemulsification compared with extracapsular cataract surgery. Ophthalmology. 2004;111:679–85.
Yamazoe K, Yamaguchi T, Hotta K, et al. Outcomes of cataract surgery in eyes with a low corneal endothelial cell density. J Cataract Refract Surg. 2011;37:2130–6.
Price MO, Price Jr FW. Cataract progression and treatment following posterior lamellar keratoplasty. J Cataract Refract Surg. 2004;30:1310–5.
Price MO, Price DA, Fairchild KM, et al. Rate and risk factors for cataract formation and extraction after Descemet stripping endothelial keratoplasty. Br J Ophthalmol. 2010;94:1468–71.
Tsui JYM, Goins KM, Sutphin JE, et al. Phakic Descemet stripping automated endothelial keratoplasty: prevalence and prognostic impact of postoperative cataracts. Cornea. 2011;30:291–5.
Burkhart ZN, Feng MT, Price Jr FW, et al. One-year outcomes in eyes remaining phakic after Descemet membrane endothelial keratoplasty. J Cataract Refract Surg. 2014;40:430–4.
Payant JA, Gordon LW, VanderZwaag R, et al. Cataract formation following corneal transplantation in eyes with Fuchs’ endothelial dystrophy. Cornea. 1990;9:286–9.
Martin TP, Reed JW, Legault C, et al. Cataract formation and cataract extraction after penetrating keratoplasty. Ophthalmology. 1994;101:113–9.
Dapena I, Yeh RY, Quilendrino R, et al. Surgical step to facilitate phacoemulsification after Descemet membrane endothelial keratoplasty. J Cataract Refract Surg. 2012;38:1106–7.
American Academy of Ophthalmology Anterior Segment Panel, Preferred Practice Pattern Guidelines. Cataract in the adult eye. San Francisco: American Academy of Ophthalmology; 2001.
Seitzman GD, Gottsch JD, Stark WJ. Cataract surgery in patients with Fuchs’ corneal dystrophy: expanding recommendations for cataract surgery without simultaneous keratoplasty. Ophthalmology. 2005;112:441–6.
Van Cleynenbreugel H, Remeijer L, Hillenaar T. Cataract surgery in patients with Fuchs’ endothelial corneal dystrophy: when to consider a triple procedure. Ophthalmology. 2014;121:445–53.
Melles GR. Posterior lamellar keratoplasty: DLEK to DSEK to DMEK. Cornea. 2006;25:879–81.
Gorovoy MS. Descemet-stripping automated endothelial keratoplasty. Cornea. 2006;25:886–9.
Chang ST, Yamagata AS, Afshari NA. Pearls for successful cataract surgery with endothelial keratoplasty. Curr Opin Ophthalmol. 2014;25:335–9.
Terry MA. Endothelial keratoplasty: clinical outcomes in the two years following deep lamellar endothelial keratoplasty (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2007;105:530–63.
Heidemann DG, Dunn SP, Chow CY. Comparison of deep lamellar endothelial keratoplasty and penetrating keratoplasty in patients with Fuchs endothelial dystrophy. Cornea. 2008;27:161–7.
Rao SK, Leung CK, Cheung CY, et al. Descemet stripping endothelial keratoplasty: effect of the surgical procedure on corneal optics. Am J Ophthalmol. 2008;145:991–6.
Koenig SB, Covert DJ, Dupps Jr WJ, et al. Visual acuity, refractive error, and endothelial cell density six months after Descemet stripping and automated endothelial keratoplasty (DSAEK). Cornea. 2007;26:670–4.
Jun B, Kuo AN, Afshari NA, et al. Refractive change after descemet stripping automated endothelial keratoplasty surgery and its correlation with graft thickness and diameter. Cornea. 2009;28:19–23.
Price MO, Giebel AW, Fairchild KM, et al. Descemet’s membrane endothelial keratoplasty: prospective multicenter study of visual and refractive outcomes and endothelial survival. Ophthalmology. 2009;116:2361–8.
Ham L, Dapena I, Moutsouris K, et al. Refractive change and stability after Descemet membrane endothelial keratoplasty. Effect of corneal dehydration-induced hyperopic shift on intraocular lens power calculation. J Cataract Refract Surg. 2011;37:1455–64.
Dupps Jr WJ, Qian Y, Meisler DM. Multivariate model of refractive shift in Descemet-stripping automated endothelial keratoplasty. J Cataract Refract Surg. 2008;34:578–84.
Hwang RY, Gauthier DJ, Wallace D, et al. Refractive changes after descemet stripping endothelial keratoplasty: a simplified mathematical model. Invest Ophthalmol Vis Sci. 2011;52:1043–54.
Scorcia V, Matteoni S, Scorcia GB, et al. Pentacam assessment of posterior lamellar grafts to explain hyperopization after Descemet’s stripping automated endothelial keratoplasty. Ophthalmology. 2009;116:1651–5.
Holz HA, Meyer JJ, Espandar L, et al. Corneal profile analysis after Descemet stripping endothelial keratoplasty and its relationship to postoperative hyperopic shift. J Cataract Refract Surg. 2008;34:211–4.
Bonfadini G, Ladas JG, Moreira H, et al. Optimization of intraocular lens constant improves refractive outcomes in combined endothelial keratoplasty and cataract surgery. Ophthalmology. 2013;120:234–9.
de Sanctis U, Damiani F, Brusasco L, et al. Refractive error after cataract surgery combined with descemet stripping automated endothelial keratoplasty. Am J Ophthalmol. 2013;156:254–9.
Terry MA, Shamie N, Chen ES, et al. Precut tissue for Descemet’s stripping automated endothelial keratoplasty: vision, astigmatism, and endothelial survival. Ophthalmology. 2009;116:248–56.
Scorcia V, Lucisano A, Beltz J, et al. Combined Descemet-stripping automated endothelial keratoplasty and phacoemulsification with toric intraocular lens implantation for treatment of failed penetrating keratoplasty with high regular astigmatism. J Cataract Refract Surg. 2012;38:716–9.
van Dijk K, Droutsas K, Hou J, et al. Optical quality of the cornea after Descemet membrane endothelial keratoplasty. Am J Ophthalmol. 2014;158:71–9.
Patel SV, Baratz KH, Maguire LJ, et al. Anterior corneal aberrations after Descemet’s stripping endothelial keratoplasty for Fuchs’ endothelial dystrophy. Ophthalmology. 2012;119:1522–9.
Rudolph M, Laaser K, Bachmann BO, et al. Corneal higher-order aberrations after Descemet’s membrane endothelial keratoplasty. Ophthalmology. 2012;119:528–35.
Patryn E, van der Meulen IJ, Lapid-Gortzak R, et al. Intraocular lens opacifications in Descemet stripping endothelial keratoplasty patients. Cornea. 2012;31:1189–92.
Fellman MA, Werner L, Liu ET, et al. Calcification of a hydrophilic acrylic intraocular lens after Descemet-stripping endothelial keratoplasty: case report and laboratory analyses. J Cataract Refract Surg. 2013;39:799–803.
Oberg TJ, Sikder S, Jorgensen AJ, et al. Topical-intracameral anesthesia without preoperative mydriatic agents for Descemet-stripping automated endothelial keratoplasty and phacoemulsification cataract surgery with intraocular lens implantation. J Cataract Refract Surg. 2012;38:384–6.
Fang JP, Hamill MB. Descemet’s stripping endothelial keratoplasty under topical anesthesia. J Cataract Refract Surg. 2007;33:187–8.
Price FW, Price MO. DSEK: what you need to know about endothelial keratoplasty. Thorofare: SLACK Incorporated; 2009.
Dirisamer M, Dapena I, Ham L, et al. Patterns of corneal endothelialization and corneal clearance after descemet membrane endothelial keratoplasty for Fuchs endothelial dystrophy. Am J Ophthalmol. 2011;152:543–55.
Anshu A, Planchard B, Price MO, et al. A cause of reticular interface haze and its management after descemet stripping endothelial keratoplasty. Cornea. 2012;31:1365–8.
Juthani VV, Goshe JM, Srivastava SK, et al. Association between transient interface fluid on intraoperative OCT and textural interface opacity after DSAEK surgery in the PIONEER study. Cornea. 2014;33:887–92.
Mehta JS, Hantera MM, Tan DT. Modified air-assisted descemetorhexis for Descemet-stripping automated endothelial keratoplasty. J Cataract Refract Surg. 2008;34:889–91.
Melles GR, Ong TS, Ververs B, et al. Descemet membrane endothelial keratoplasty (DMEK). Cornea. 2006;25:987–90.
Price MO, Price Jr FW. Descemet’s membrane endothelial keratoplasty surgery: update on the evidence and hurdles to acceptance. Curr Opin Ophthalmol. 2013;24:329–35.
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Woo, J.H., Mehta, J.S. (2016). Endothelial Keratoplasty Combined with Cataract Extraction. In: Jacob, S. (eds) Mastering Endothelial Keratoplasty . Springer, New Delhi. https://doi.org/10.1007/978-81-322-2821-9_1
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DOI: https://doi.org/10.1007/978-81-322-2821-9_1
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