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Enterohemorrhagic E. coli Infections

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Confronting Emerging Zoonoses

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Abstract

…there is always some little thing that is too big for us

Don Marquis, Archy and Mehitabel, 1929

Enterohemorrhagic E. coli (EHEC) represent a classic example for the role of the One Health paradigm. A silent barnyard colonizer of ruminants, this zoonotic group of organisms was recognized to have jumped the species barrier to humans barely three decades ago and now is an human enteric infection which is the most common cause of acute kidney failure in children. Transmitted primarily through a breakdown in the food chain that facilitates contamination by some of the world’s overwhelming amount of bovine manure, EHEC demonstrate a great deal of genetic diversity and clearly show the ability to develop into more virulent strains. EHEC also have interactions with a spate of other life forms including viruses, fungi, protozoa and plants.

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  1. Medicine and Biomedical Sciences, Homer Stryker MD School of Medicine, Western Michigan University, 1000 Oakland Drive, Kalamazoo, MI, 49008, USA

    Larry I. Lutwick MD

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  1. Department of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

    Akio Yamada

  2. Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, New Jersey, USA

    Laura H. Kahn

  3. (emeritus), Sarasota, Florida, USA

    Bruce Kaplan

  4. Hookipa BioTech AG, Townsend, Massachusetts, USA

    Thomas P. Monath

  5. (emeritus), Rio de Janeiro, Brazil

    Jack Woodall

  6. Florida Department of Agriculture and Consumer Services, Tallahassee, Florida, USA

    Lisa Conti

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Lutwick, L.I. (2014). Enterohemorrhagic E. coli Infections. In: Yamada, A., Kahn, L., Kaplan, B., Monath, T., Woodall, J., Conti, L. (eds) Confronting Emerging Zoonoses. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55120-1_5

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