Abstract
After the dramatic improvement of multiple sclerosis patients reported by Cook and Weinstein (1973), spinal cord stimulation (SCS) for the relief of spasticity and motor dyskinesias has been applied to a large number of patients. However, the overall effectiveness of this treatment has been a subject of considerable debate, some authors even reaching the conclusion that the observed results can be explained in terms of a placebo effect (Rosen and Barsoum 1979). In this review we will try to answer the question which is most important from the patient’s point of view: (1) What is the effect of SCS on spasticity and accompanying motor impairment? We will also examine the data which are available with respect to the following questions which are important for the physician: (2) Is there a difference between the effect of SCS in MS patients, who have a fluctuating clinical course, and patients with other conditions, such as cerebral palsy, trauma, and cerebellar atrophies, in which the clinical course is either stabilized or progressive?
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Barolat-Romana G, Myklebust JB (1986) Immediate effects of spinal cord stimulation on spinal spasticity. Presented at 7th Meeting ESSFN, Birmingham
Barolat-Romana G, Myklebust JB, Hemmy DC, Myklebust B, Wenninger W (1985) Immediate effects of spinal cord stimulation in spinal spasticity. J Neurosurg 62:558–562
Barolat G, Myklebust JB, Wenninger W (1988) Effects of spinal cord stimulation in spasticity and spasms secondary to myelopathy. Appl Neurophysiol 51:29–44
Berg V, Bergmann S, Hovdal H, Hunstad N, Johnsen HJ, Levin L, Sjaastad O (1982) The value of dorsal column stimulation in multiple sclerosis. Scand J Rehabil Med 14:183–191
Broseta J, Garcia-March G, Sanchez-Ledesma MJ, Barbera J, Gonzalez-Darder J (1987) High-frequency cervical spinal cord stimulation in spasticity and motor disorders. Acta Neurochir [Suppl] 39:112–116
Campos RJ, Dimitrijevic MM, Faganel J, Sharkey PC (1981) Clinical evaluation of the effect of spinal cord stimulation on motor performance in patients with upper motor neuron lesions. Appl Neurophysiol 44:141–151
Campos RJ, Dimitrijevic MR, Sharkey PC, Sherwood AM (1987) Epidural spinal cord stimulation in spastic spinal cord injury patients. Appl Neurophysiol 50:453–454
Cioni B, Meglio M (1987) Spinal cord stimulation improves motor performances in hemiplegics: clinical and neurophysiological study. Acta Neurochir [Suppl] 39:103–105
Cook AW (1976) Electrical stimulation in multiple sclerosis. Hosp Pract 11:51–58
Cook AW, Weinstein SP (1973) Chronic dorsal column stimulation in multiple sclerosis. NY St J Med 73:2868–2872
Cook AW, Taylor JK, Nidzgorski F (1981) Results of spinal cord stimulation in multiple sclerosis. Appl Neurophysiol 44:55–61
Davis R, Gray E, Kudzma J (1981) Beneficial augmentation following dorsal column stimulation in some neurological diseases. Appl Neurophysiol 44:37–49
Dimitrijevic MR, Faganel J, Young RR (1981) Underlying mechanisms of the effects of spinal cord stimulation in motor disorders. Appl Neurophysiol 44:133–140
Dimitrijevic MM, Dimitrijevic MR, Illis LS, Nakajima K, Sharkey PC, Sherwood AM (1986a) Spinal cord stimulation for the control of spasticity in patients with chronic spinal cord injury. I. Clinical observations. Central nervous system trauma 3:129–144
Dimitrijevic MR, Illis LS, Nakajima K, Sharkey PC, Sherwood AM (1986b) Spinal cord stimulation for the control of spasticity in patients with chronic spinal cord injury. II. Neurophysiologic observations. Central nervous system trauma 3:145–152
Dooley DM (1977) Demyelinating, degenerative and vascular disease. Neurosurgery 1:220–224
Dooley DM, Nisonson I (1981) Treatment of patients with degenerative diseases of the central nervous system by electrical stimulation of the spinal cord. Appl Neurophysiol 44:71–76
Dooley DM, Sharkey J (1981) Electrical stimulation of the spinal cord in patients with demyelinating and degenerative diseases of the central nervous system. Appl Neurophysiol 44:218–224
Fredriksen TA, Bergmann S, Hesselberg JP, Stolt-Nielsen A, Ringkjob R, Sjaastad O (1986) Electrical stimulation in multiple sclerosis. Comparison of transcutaneous electrical stimulation and epidural spinal cord stimulation. Appl Neurophysiol 49:4–24
Gildenberg PL (1978) Treatment of spasmodic torticollis by dorsal column stimulation. Appl Neurophysiol 41:113–121
Gildenberg PL (1981) Comprehensive management of spasmodic torticollis. Appl Neurophysiol 44:233–243
Gottlieb GL, Myklebust BM, Stefoski D, Groth K, Kroin J, Penn RD (1985) Evaluation of cervical stimulation for chronic treatment of spasticity. Neurology 35:699–704
Gybels J, Van Roost D (1985) Spinal cord stimulation for the modification of dystonic and hyperkinetic conditions. A critical review. In: Eccles JC, Dimitrijevic ME (eds) Recent achievements in restorative neurology. 1. Upper motor neuron functions and dysfunctions. Karger, Basel, pp 56–70
Gybels J, Van Roost D (1987) Spinal cord stimulation for spasticity. In: Symon et al (eds) Advances and technical standards in neurosurgery, vol 15. Springer, Wien, pp 63–96
Hawkes CH, Fawcett D, Cooke ED, Emson PC, Paul EA, Bowcock SA (1981) Dorsal column stimulation in multiple sclerosis: effects on bladder, e.g. blood flow and peptides. Appl Neurophysiol 44:62–70
Hawkes CH, Beard R, Fawcett D, Paul EA, Thomas DGT (1983) Dorsal column stimulation in multiple sclerosis; effects on bladder and long term findings. Br Med J 287:793–795
Hugenholtz H, Humphreys P, McIntyre WMJ, Spasoff RA, Steel K (1988) Cervical spinal cord stimulation for spasticity in cereral palsy. Neurosurgery 22:707–714
Illis LS (1973) Regeneration in the central nervous system. Lancet i:1035–1037
Illis LS (1983) Central nervous stimulation in neurological disease. J Roy Soc Med 76:905–909
Illis LS, Sedgwick EM, Oygar AE, Sabbahi Awadalla MA (1976) Dorsal column stimulation in the rehabilitation of patients with multiple sclerosis. Lancet i:1383–1386
Illis LS, Sedgwick EM, Tallis RC (1980) Spinal cord stimulation in multiple sclerosis: clinical results. J Neural Neurosurg Psychiatry 43:1–14
Illis LS, Read DJ, Sedgwick EM, Tallis RC (1983) Spinal cord stimulation in the United Kingdom. J Neurol Neurosurg Psychiatry 46:299–304
Ketelaer P, Swartenbroeckx G, Deltenre P, Carton H, Gybels J (1979) Percutaneous epidural dorsal cord stimulation in multiple sclerosis. Acta Neurochir (Wien) 49:95–101
Klinger D, Kepplinger B (1982) Quantification of the effects to epidural spinal electrostimulation (ESES) in central motor disorders. Appl Neurophysiol 45:221–224
Koulousakis A, Buchhaas U, Nittner K (1987) Application of SCS for movement disorders and spasticity. Acta Neurochir [Suppl] 39:112–116
Lazorthes Y, Siegfried J, Broggi G (1981) Electrical spinal cord stimulation for spastic motor disorders in demyelinating diseases — a cooperative study. In: Hosobuchi Y, Corbin I (eds) Indications for spinal cord stimulation. Excerpta Medica, Princeton, pp 48–57
Maiman DJ, Myklebust JB, Barolat-Romana G (1987) Spinal cord stimulation for amelioration of spasticity: experimental results. Neurosurgery 21:331–333
Nakamura S, Tsubokawa T (1985) Evaluation of spinal cord stimulation for postapoplectic spastic hemiplegia. Neurosurgery 17:253–259
Plotkin R (1980) Pisces stimulation for motor neurone disease. Acta Neurochir [Suppl] 30:429–433
Read DJ, Matthews WB, Higson RH (1980) The effect of spinal cord stimulation on function in patients with multiple sclerosis. Brain 103:803–833
Reynolds AF, Oakley JC (1982) High frequency cervical epidural stimulation for spasticity. Appl Neurophysiol 45:93–97
Richardson RR, Cerullo LJ, McLone DG, Gutierrez FA, Lewis V (1979) Percutaneous epidural neurostimulation in modulation of paraplegic spasticity. Six case reports. Acta Neurochir (Wien) 49:235–243
Rosen JA, Barsoum AH (1979) Failure of chronic dorsal column stimulation in multiple sclerosis. Ann Neurol 6:66–67
Scerrati M, Onofrio J, Pola P (1982) Effects of spinal cord stimulation on spasticity. H-reflex study. Appl Neurophysiol 45:62–67
Sedgwick EM, Illis LS, Tallis RC, Thornton ARD, Abraham P, El-Negamy E, Docherty TB, Soar JS, Spencer SC, Taylor FM (1980) Evoked potentials and contingent negative variation during treatment of multiple sclerosis with spinal cord stimulation. J Neurol Neurosurg Psychiatry 43:15–24
Sharkey PC, Dimitrijevic MM, Campos RJ, Dimitrijevic MR (1981) Remarks on spinal cord stimulation and the placebo effect. Appl Neurophysiol 44:119–125
Siegfried J (1980) Treatment of spasticity by dorsal cord stimulation. Int Rehab Med 2:31–34
Siegfried J, Krainick JU, Haas H, Adorjani C, Meyer M, Thoden U (1978) Electrical spinal cord stimulation for spastic movement disorders. Appl Neurophysiol 41:134–141
Spiegel EA (1982) Relief of pain and spasticity by posterior column stimulation. A proposed mechanism. Archs Neurol (Chicago) 39:184–185
Tallis RC, Illis LS, Smedgwick EM (1983) The quantitative assessment of the influence of spinal cord stimulation on motor function in patients with multiple sclerosis. Int Rehab Med 5:10–16
Walker JB (1982) Modulation of spasticity: prolonged suppression of a spinal reflex by electrical stimulation. Science 216:203–204
Waltz JM (1982) Computerized percutaneous multi-level spinal cord stimulation in motor disorders. Appl Neurophysiol 45:73–92
Waltz JM, Andreesen WH (1981) multiple-lead spinal cord stimulation: technique. Appl Neurophysiol 44:30–36
Waltz JM, Davis JA (1983) Cervical cord stimulation in the treatment of athetosis and dystonia. Adv Neurol 37:225–237
Waltz JM, Reynolds LO, Riklan M (1981) Multi-lead spinal cord stimulation for control of motor disorders. Appl Neurophysiol 44:244–257
Wiesendanger M, Chapman CE, Marini G, Schorderet D (1985) Experimental studies of dorsal cord stimulation in animal models of spasticity. In: Delwaide PJ, Young RR (eds) Clinical neurophysiology in spasticity. Elsevier Science Publishers BV, Amsterdam, pp 205–219
Young RF, Goodman SJ (1979) Dorsal spinal cord stimulation in the treatment of multiple sclerosis. Neurosurgery 5:225–230
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer-Verlag Wien
About this chapter
Cite this chapter
Gybels, J., Van Roost, D. (1991). Spinal cord stimulation for spasticity. In: Sindou, M.P., Abbott, I.R., Keravel, Y. (eds) Neurosurgery for Spasticity. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6708-3_11
Download citation
DOI: https://doi.org/10.1007/978-3-7091-6708-3_11
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-7388-6
Online ISBN: 978-3-7091-6708-3
eBook Packages: Springer Book Archive