Abstract
The ventricular system (i.e., lateral ventricles, third ventricle, and fourth ventricle) is composed of hollow cavities which are located in the telencephalon, diencephalon, and mesencephalon and extend via the pons to the medulla. They harbor the cerebrospinal fluid (CSF) which is produced by the choroid plexuses and fulfills nutritive and protective functions of the brain. The exchange of chemical substances between the arterial blood, the CSF and the brain is regulated by the barrier system which is made up of the blood–brain barrier (BBB), the brain–liquor barrier (BLB), and the blood–liquor barrier.
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Selected References
Benarroch EE (2016) Choroid plexus—CSF system: recent developments and clinical correlations. Neurology 86(3):286–296. https://doi.org/10.1212/wnl.0000000000002298
Heimer L (1983) The human brain and spinal cord: functional neuroanatomy and dissection guide. Springer, Berlin, Heidelberg
Kaur C, Rathnasamy G, Ling EA (2016) The choroid plexus in healthy and diseased brain. J Neuropathol Exp Neurol 75(3):198–213. https://doi.org/10.1093/jnen/nlv030
Lehtinen MK, Bjornsson CS, Dymecki SM, Gilbertson RJ, Holtzman DM, Monuki ES (2013) The choroid plexus and cerebrospinal fluid: emerging roles in development, disease, and therapy. J Neurosci 33(45):17553–17559. https://doi.org/10.1523/jneurosci.3258-13.2013
Lun MP, Monuki ES, Lehtinen MK (2015) Development and functions of the choroid plexus-cerebrospinal fluid system. Nat Rev Neurosci 16(8):445–457. https://doi.org/10.1038/nrn3921
Marques F, Sousa JC, Brito MA, Pahnke J, Santos C, Correia-Neves M, Palha JA (2017) The choroid plexus in health and in disease: dialogues into and out of the brain. Neurobiol Dis 107:32–40. https://doi.org/10.1016/j.nbd.2016.08.011
McLone DG (2004) The anatomy of the ventricular system. Neurosurg Clin N Am 15(1):33–38. https://doi.org/10.1016/s1042-3680(03)00073-1
Mortazavi MM, Adeeb N, Griessenauer CJ, Sheikh H, Shahidi S, Tubbs RI, Tubbs RS (2014a) The ventricular system of the brain: a comprehensive review of its history, anatomy, histology, embryology, and surgical considerations. Childs Nerv Syst 30(1):19–35. https://doi.org/10.1007/s00381-013-2321-3
Mortazavi MM, Griessenauer CJ, Adeeb N, Deep A, Bavarsad Shahripour R, Loukas M, Tubbs RI, Tubbs RS (2014b) The choroid plexus: a comprehensive review of its history, anatomy, function, histology, embryology, and surgical considerations. Childs Nerv Syst 30(2):205–214. https://doi.org/10.1007/s00381-013-2326-y
Spector R, Keep RF, Robert Snodgrass S, Smith QR, Johanson CE (2015) A balanced view of choroid plexus structure and function: focus on adult humans. Exp Neurol 267:78–86. https://doi.org/10.1016/j.expneurol.2015.02.032
Stratchko L, Filatova I, Agarwal A, Kanekar S (2016) The ventricular system of the brain: anatomy and normal variations. Semin Ultrasound CT MR 37(2):72–83. https://doi.org/10.1053/j.sult.2016.01.004
Weis S, Thaller R, Villringer A, Wenger E (1992) Das Gehirn des Menschen. Morphologie, Kernspintomographie und 3D-Computerrekonstruktion. Hogrefe, Göttingen
Wolburg H, Paulus W (2010) Choroid plexus: biology and pathology. Acta Neuropathol 119(1):75–88. https://doi.org/10.1007/s00401-009-0627-8
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Weis, S. et al. (2019). Ventricular System: Cerebrospinal Fluid (CSF)—Barriers. In: Imaging Brain Diseases. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1544-2_6
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DOI: https://doi.org/10.1007/978-3-7091-1544-2_6
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