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Die Schmerzmatrix und chronisch degenerative Erkrankungen

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Bewegungsmangel

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Zusammenfassung

Am Erregungsmuster des Gehirns, der „Neurosignatur“, sind alle Netzwerke, insgesamt die „Neuromatrix“ beteiligt und vertritt die Motivation, die Emotionen, die Stressbewältigung, die Handlungsregulation und die Körperwahrnehmung. Bei chronischen Schmerzen ist sie maladaptiv verändert und wird zur „Schmerzmatrix“, die das Verhalten und die Resilience des Schmerzpatienten bestimmen.

Das MRI mach anhand von Reorganisationen, reduzierten Volumina und veränderte Verknüpfungen der Hirnareale die Maladaptationen sichtbar. Diese Befunde entsprechen einem vorzeitigen Altern. Die Bewältigung von Aufgaben leidet. Emotionen und die Kognition sind mehr als die Schmerzverarbeitung betroffen. Die zentrale Sensibilisierung demonstriert.

Mit dem Alter liefert die Hirnstruktur eine Disposition für Defizite der Schmerzmodulation. Das physiologische Altern ist aber keine Ursache von Schmerzsyndromen. Liegen Schmerzen vor, stimulieren sie das Altern. Die Gesundheit geht mit der strukturellen Integrität des Gehirns parallel.

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Laube, W. (2023). Die Schmerzmatrix und chronisch degenerative Erkrankungen. In: Bewegungsmangel. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-67753-7_13

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