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Genetik, Epidemiologie und Prävention

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Kinderallergologie in Klinik und Praxis

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Zusammenfassung

In der Pathogenese allergischer Erkrankungen kommt es zu einer komplexen Interaktion zwischen genetischer Veranlagung und Umweltfaktoren. So ist die familiäre Prädisposition zu Erkrankungen wie Asthma bronchiale, allergischer Rhinitis oder dem atopischen Ekzem gut belegt. Beispielsweise steigt das Asthmarisiko eines Kindes auf ca. 30–50 %, wenn ein Familienmitglied ersten Grades an Asthma bronchiale erkrankt ist. In gleichem Sinne tritt ein atopisches Ekzem bei eineiigen Zwillingen mit einer Konkordanz von ca. 75 % auf, während dizygote Zwillinge nur in ca. 20 % der Fälle gemeinsam erkranken.

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Hilfreiche Websites

  • http://www.gpau.de – Gesellschaft für Pädiatrische Allergologie und Umweltmedizin: Elternratgeber „Allergieprävention“

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  • http://www.kindergesundheit-info.de – Bundeszentrale für gesundheitliche Aufklärung: Umfangreiche Eltern-/Patienteninformationen

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Authors and Affiliations

  1. Universitätsklinik für Kinderheilkunde Inselspital, Universität Bern, Bern, Schweiz

    Prof. Dr. med. Matthias V. Kopp

  2. Pädiatrische Dermatologie und Allergologie Zentrum für Seltene Angeborene Hauterkrankungen, Kinder- und Jugendkrankenhaus AUF DER BULT, Hannover, Deutschland

    Prof. Dr. med. Hagen Ott

  3. Pneumologie und Allergologie, St.-Marien-Hospital, Bonn, Deutschland

    Dr. med. Lars Lange

Authors
  1. Prof. Dr. med. Matthias V. Kopp
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  2. Prof. Dr. med. Hagen Ott
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  3. Dr. med. Lars Lange
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Correspondence to Matthias V. Kopp .

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Kopp, M.V., Ott, H., Lange, L. (2023). Genetik, Epidemiologie und Prävention. In: Kinderallergologie in Klinik und Praxis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-62714-3_2

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  • DOI: https://doi.org/10.1007/978-3-662-62714-3_2

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  • Print ISBN: 978-3-662-62713-6

  • Online ISBN: 978-3-662-62714-3

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