Skip to main content

Therapie mikroskopischer Kolitiden und eosinophiler Erkrankungen des Gastrointestinaltraktes

  • Chapter
  • First Online:
Chronisch-entzündliche Darmerkrankungen
  • 3602 Accesses

Zusammenfassung

Die Therapie der mikroskopischen Kolitis orientiert sich an dem Schweregrad der Symptome, dem Leidensdruck des Patienten und der Verfügbarkeit von Effektivitätsdaten aus randomisierten, kontrollierten Studien.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Baert F, Schmit A, D’Haens G, Dedeurwaerdere F, Louis E, Cabooter M, De Vos M, Fontaine F, Naegels S, Schurmans P, Stals H, Geboes K, Rutgeerts P (2002) Budesonide in collagenous colitis – a double-blind placebo-controlled trial with histological follow-up. Gastroenterology 122:20–25

    Article  CAS  Google Scholar 

  • Bonderup OK, Hansen JB, Birket-Smith L, Vestergaard V, Teglbjaerg PS, Fallingborg J (2003) Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis. Gut 52:248–251

    Article  CAS  Google Scholar 

  • Bonderup OK, Hansen JB, Teglbjaerg PS, Christensen LA, Fallingborg JF (2009) Long-term budesonide treatment of collagenous colitis – a randomised, double-blind, placebo-controlled trial. Gut 58:68–72

    Article  CAS  Google Scholar 

  • Chande N, McDonald JWD, MacDonald JK (2008a) Interventions for treating collagenous colitis. Cochrane Database Syst Rev 16(2):CD003575. https://doi.org/10.1002/14651858.cd003575.pub5

  • Chande N, McDonald JWD, MacDonald JK (2008b) Interventions for treating lymphocytic colitis. Cochrane Database Syst Rev 16(2):CD006096. https://doi.org/10.1002/14651858.cd006096.pub3 Colitis: A Systematic Review and Meta-analysis. Clin Gastroenterol

  • Chande N, MacDonald JK, McDonald JW (2009) Interventions for treating microscopic colitis: a Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders Review Group systematic review of randomized controlled trials. Am J Gastroenterol 104:235–241

    Article  CAS  Google Scholar 

  • Cotter TG, Kamboj AK, Hicks SB, Tremaine WJ, Loftus EV, Pardi DS (2017) Immune modulator therapy for microscopic colitis in a case series of 73 patients. Aliment Pharmacol Ther 46:169–174

    Article  CAS  Google Scholar 

  • Delarive J, Saraga E, Dorta G, Blum A (1998) Budesonide in the treatment of collagenous colitis. Digestion 59:364–366

    Article  CAS  Google Scholar 

  • Foroughi S, Foster B, Kim N et al (2007) Anti-IgE treatment of eosinophil-associated gastrointestinal disorders. J Allergy Clin Immunol 120:594–601

    Article  CAS  Google Scholar 

  • Hjortswang C, Tysk C, Bohr J, Benoni C, Kilander A, Larsson L et al (2009) Defining clinical criteria for clinical remission and disease activity in collagenous colitis. Inflamm Bowel Dis 15:1875–1881

    Article  Google Scholar 

  • Kagalwalla AF, Sentongo TA, Ritz S (2006) Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol 4:1097–1102

    Article  Google Scholar 

  • Kim YJ, Prussin C, Martin B et al (2004) Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700. J Allergy Clin Immunol 114:1449–1455

    Article  CAS  Google Scholar 

  • Madisch A, Heymer P, Voss C, Wigginhaus B, Bästlein E, Bayerdörffer E, Meier E, Schimming W, Bethke B, Stolte M, Miehlke S (2005) Oral Budesonide therapy improves quality of life in patients with collagenous colitis – results of placebo-controlled, multicenter trial. Int J Colorectal Dis 20:312–316

    Google Scholar 

  • Miehlke S, Heymer P, Bethke B, Bästlein E, Meier E, Bartram HP, Wilhelms G, Lehn N, Dorta G, DeLarive J, Tromm A, Bayerdörffer E, Stolte M (2002) Budesonide treatment for collagenous colitis – a randomized, double- blind, placebo-controlled, multicenter trial. Gastroenterology 123:978–984

    Article  CAS  Google Scholar 

  • Miehlke S, Madisch A, Bethke B, Stolte M (2005a) Time to remission with budesonide in collagenous colitis. Aliment Pharmacol Ther 21:1507–1508

    Google Scholar 

  • Miehlke S, Madisch A, Voss C, Kuhlisch E, Morgner A, Heymer P, Bästlein E, Wigginghaus B, Bayerdörffer E, Stolte M (2005b) Long-term follow-up and predictive factors for clinical relapse in patients with collagenous colitis after induction of remission with budesonide capsules. Aliment Pharmacol Ther 22:1115–1119

    Article  CAS  Google Scholar 

  • Miehlke S, Madisch A, Bethke B, Morgner A, Kuhlisch E, Henker C, Vogel G, Andersen M, Meier E, Baretton G, Stolte M (2008) Oral budesonide for maintenance treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial. Gastroenterology 135:1510–1516

    Google Scholar 

  • Miehlke S, Madisch A, Karimi D, Wonschik S, Kuhlisch E, Beckmann R, Morgner A, Mueller R, Greinwald R, Seitz G, Baretton G, Stolte M (2009) Budesonide is effective in treating lymphocytic colitis: a randomized double-blind placebo-controlled study. Gastroenterology 136:2092–2100

    Article  CAS  Google Scholar 

  • Miehlke S, Aust D, Madisch A (2013) Microscopic colitis–new insights relevant to clinical practice. Z Gastroenterol 51:1389–1394

    Article  CAS  Google Scholar 

  • Miehlke S, Madisch A, Kupcinskas L, Petrauskas D, Böhm G, Marks HJ, Neumeyer M, Nathan T, Fernández-Bañares F, Greinwald R, Mohrbacher R, Vieth M, Bonderup OK, BUC-60/COC Study Group (2014) Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis. Gastroenterology 146:1222–1230

    Article  CAS  Google Scholar 

  • Miehlke S, Aust D, Mihaly E, Armerding P, Böhm G, Bonderup O, Fernández-Bañares F, Kupcinskas J, Munck L, Rehbehn KU, Nacak T, Greinwald R, Münch A, BUG-1/LMC Study Group (2018) Efficacy and Safety of Budesonide, vs Mesalazine or Placebo, as induction therapy for lymphocytic colitis. Gastroenterology 155(6):1795–1804

    Article  CAS  Google Scholar 

  • Münch A, Ignatova S, Ström M (2012) Adalimumab in budesonide and methotrexate refractory collagenous colitis. Scand J Gastroenterol 47:59–63

    Article  Google Scholar 

  • Münch A, Fernandez-Banares F, Munck LK (2013) Azathioprine and mercaptopurine in the management of patients with chronic, active microscopic colitis. Aliment Pharmacol Ther 37:795–798

    Article  Google Scholar 

  • Münch A, Bohr J, Miehlke S, Benoni C, Olesen M, Öst A, Strandberg L, Hellström PM, Hertervig E, Armerding P, Stehlik J, Lindberg G, Björk J, Lapidus A, Löfberg R, Bonderup O, Avnström S, Rössle M, Dilger K, Mueller R, Greinwald R, Tysk C, Ström M, BUC-63 Investigators (2016) Low-dose budesonide for maintenance of clinical remission in collagenous colitis: a randomised, placebo-controlled, 12-month trial. Gut 65:47–56

    Article  Google Scholar 

  • Pardi DS, Loftus EV, Tremaine WJ et al (2009) A randomized, double-blind, placebo-controlled trial of budesonide for the treatment of active lymphocytic colitis. Gastroenterol 136:A519

    Article  Google Scholar 

  • Siewert E, Lammert F, Koppitz P, Schmidt T, Matern S (2006) Eosinophilic gastroenteritis with severe protein-losing enteropathy: successful treatment with budesonide. Dig Liver Dis 38:55–59

    Article  CAS  Google Scholar 

  • Stewart MJ, Seow CH, Storr MA (2011) Prednisolone and budesonide for short- and long-term treatment of microscopic colitis: systematic review and meta-analysis. Clin Gastroenterol Hepatol 9:881–890

    Article  CAS  Google Scholar 

  • Tromm A, Griga T, Möllmann HW, May B, Müller KM, Fisseler-Eckhoff A (1999) Budesonide for the treatment of collagenous colitis: first results of a pilot trial. Am J Gastroenterol 94:1871–1875

    Article  CAS  Google Scholar 

  • Turner D, Wolters VM, Russell RK et al (2013) Anti-TNF, infiximab, and adalimumab can be effective in eosinophilic bowel disease. J Pediatr Gastroenterol Nutr 56:492–497

    Google Scholar 

  • Walker MM, M Potter, NJ Talley (2018) Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the oesophagus. Lancet Gastroenterol Hepatol 3:271–280

    Google Scholar 

  • Zhang M, Li Y (2017) Eosinophilic gastroenteritis: A state-of-the-art review. J Gastroenterol Hepatol 32:64–72

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ahmed Madisch .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Madisch, A., Miehlke, S. (2020). Therapie mikroskopischer Kolitiden und eosinophiler Erkrankungen des Gastrointestinaltraktes. In: Hoffmann, J.C., Klump, B., Kroesen, A., Siegmund, B. (eds) Chronisch-entzündliche Darmerkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59104-8_26

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-59104-8_26

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-59103-1

  • Online ISBN: 978-3-662-59104-8

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics