Zusammenfassung
Die Therapie der mikroskopischen Kolitis orientiert sich an dem Schweregrad der Symptome, dem Leidensdruck des Patienten und der Verfügbarkeit von Effektivitätsdaten aus randomisierten, kontrollierten Studien.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literatur
Baert F, Schmit A, D’Haens G, Dedeurwaerdere F, Louis E, Cabooter M, De Vos M, Fontaine F, Naegels S, Schurmans P, Stals H, Geboes K, Rutgeerts P (2002) Budesonide in collagenous colitis – a double-blind placebo-controlled trial with histological follow-up. Gastroenterology 122:20–25
Bonderup OK, Hansen JB, Birket-Smith L, Vestergaard V, Teglbjaerg PS, Fallingborg J (2003) Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis. Gut 52:248–251
Bonderup OK, Hansen JB, Teglbjaerg PS, Christensen LA, Fallingborg JF (2009) Long-term budesonide treatment of collagenous colitis – a randomised, double-blind, placebo-controlled trial. Gut 58:68–72
Chande N, McDonald JWD, MacDonald JK (2008a) Interventions for treating collagenous colitis. Cochrane Database Syst Rev 16(2):CD003575. https://doi.org/10.1002/14651858.cd003575.pub5
Chande N, McDonald JWD, MacDonald JK (2008b) Interventions for treating lymphocytic colitis. Cochrane Database Syst Rev 16(2):CD006096. https://doi.org/10.1002/14651858.cd006096.pub3 Colitis: A Systematic Review and Meta-analysis. Clin Gastroenterol
Chande N, MacDonald JK, McDonald JW (2009) Interventions for treating microscopic colitis: a Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders Review Group systematic review of randomized controlled trials. Am J Gastroenterol 104:235–241
Cotter TG, Kamboj AK, Hicks SB, Tremaine WJ, Loftus EV, Pardi DS (2017) Immune modulator therapy for microscopic colitis in a case series of 73 patients. Aliment Pharmacol Ther 46:169–174
Delarive J, Saraga E, Dorta G, Blum A (1998) Budesonide in the treatment of collagenous colitis. Digestion 59:364–366
Foroughi S, Foster B, Kim N et al (2007) Anti-IgE treatment of eosinophil-associated gastrointestinal disorders. J Allergy Clin Immunol 120:594–601
Hjortswang C, Tysk C, Bohr J, Benoni C, Kilander A, Larsson L et al (2009) Defining clinical criteria for clinical remission and disease activity in collagenous colitis. Inflamm Bowel Dis 15:1875–1881
Kagalwalla AF, Sentongo TA, Ritz S (2006) Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol 4:1097–1102
Kim YJ, Prussin C, Martin B et al (2004) Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700. J Allergy Clin Immunol 114:1449–1455
Madisch A, Heymer P, Voss C, Wigginhaus B, Bästlein E, Bayerdörffer E, Meier E, Schimming W, Bethke B, Stolte M, Miehlke S (2005) Oral Budesonide therapy improves quality of life in patients with collagenous colitis – results of placebo-controlled, multicenter trial. Int J Colorectal Dis 20:312–316
Miehlke S, Heymer P, Bethke B, Bästlein E, Meier E, Bartram HP, Wilhelms G, Lehn N, Dorta G, DeLarive J, Tromm A, Bayerdörffer E, Stolte M (2002) Budesonide treatment for collagenous colitis – a randomized, double- blind, placebo-controlled, multicenter trial. Gastroenterology 123:978–984
Miehlke S, Madisch A, Bethke B, Stolte M (2005a) Time to remission with budesonide in collagenous colitis. Aliment Pharmacol Ther 21:1507–1508
Miehlke S, Madisch A, Voss C, Kuhlisch E, Morgner A, Heymer P, Bästlein E, Wigginghaus B, Bayerdörffer E, Stolte M (2005b) Long-term follow-up and predictive factors for clinical relapse in patients with collagenous colitis after induction of remission with budesonide capsules. Aliment Pharmacol Ther 22:1115–1119
Miehlke S, Madisch A, Bethke B, Morgner A, Kuhlisch E, Henker C, Vogel G, Andersen M, Meier E, Baretton G, Stolte M (2008) Oral budesonide for maintenance treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial. Gastroenterology 135:1510–1516
Miehlke S, Madisch A, Karimi D, Wonschik S, Kuhlisch E, Beckmann R, Morgner A, Mueller R, Greinwald R, Seitz G, Baretton G, Stolte M (2009) Budesonide is effective in treating lymphocytic colitis: a randomized double-blind placebo-controlled study. Gastroenterology 136:2092–2100
Miehlke S, Aust D, Madisch A (2013) Microscopic colitis–new insights relevant to clinical practice. Z Gastroenterol 51:1389–1394
Miehlke S, Madisch A, Kupcinskas L, Petrauskas D, Böhm G, Marks HJ, Neumeyer M, Nathan T, Fernández-Bañares F, Greinwald R, Mohrbacher R, Vieth M, Bonderup OK, BUC-60/COC Study Group (2014) Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis. Gastroenterology 146:1222–1230
Miehlke S, Aust D, Mihaly E, Armerding P, Böhm G, Bonderup O, Fernández-Bañares F, Kupcinskas J, Munck L, Rehbehn KU, Nacak T, Greinwald R, Münch A, BUG-1/LMC Study Group (2018) Efficacy and Safety of Budesonide, vs Mesalazine or Placebo, as induction therapy for lymphocytic colitis. Gastroenterology 155(6):1795–1804
Münch A, Ignatova S, Ström M (2012) Adalimumab in budesonide and methotrexate refractory collagenous colitis. Scand J Gastroenterol 47:59–63
Münch A, Fernandez-Banares F, Munck LK (2013) Azathioprine and mercaptopurine in the management of patients with chronic, active microscopic colitis. Aliment Pharmacol Ther 37:795–798
Münch A, Bohr J, Miehlke S, Benoni C, Olesen M, Öst A, Strandberg L, Hellström PM, Hertervig E, Armerding P, Stehlik J, Lindberg G, Björk J, Lapidus A, Löfberg R, Bonderup O, Avnström S, Rössle M, Dilger K, Mueller R, Greinwald R, Tysk C, Ström M, BUC-63 Investigators (2016) Low-dose budesonide for maintenance of clinical remission in collagenous colitis: a randomised, placebo-controlled, 12-month trial. Gut 65:47–56
Pardi DS, Loftus EV, Tremaine WJ et al (2009) A randomized, double-blind, placebo-controlled trial of budesonide for the treatment of active lymphocytic colitis. Gastroenterol 136:A519
Siewert E, Lammert F, Koppitz P, Schmidt T, Matern S (2006) Eosinophilic gastroenteritis with severe protein-losing enteropathy: successful treatment with budesonide. Dig Liver Dis 38:55–59
Stewart MJ, Seow CH, Storr MA (2011) Prednisolone and budesonide for short- and long-term treatment of microscopic colitis: systematic review and meta-analysis. Clin Gastroenterol Hepatol 9:881–890
Tromm A, Griga T, Möllmann HW, May B, Müller KM, Fisseler-Eckhoff A (1999) Budesonide for the treatment of collagenous colitis: first results of a pilot trial. Am J Gastroenterol 94:1871–1875
Turner D, Wolters VM, Russell RK et al (2013) Anti-TNF, infiximab, and adalimumab can be effective in eosinophilic bowel disease. J Pediatr Gastroenterol Nutr 56:492–497
Walker MM, M Potter, NJ Talley (2018) Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the oesophagus. Lancet Gastroenterol Hepatol 3:271–280
Zhang M, Li Y (2017) Eosinophilic gastroenteritis: A state-of-the-art review. J Gastroenterol Hepatol 32:64–72
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature
About this chapter
Cite this chapter
Madisch, A., Miehlke, S. (2020). Therapie mikroskopischer Kolitiden und eosinophiler Erkrankungen des Gastrointestinaltraktes. In: Hoffmann, J.C., Klump, B., Kroesen, A., Siegmund, B. (eds) Chronisch-entzündliche Darmerkrankungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59104-8_26
Download citation
DOI: https://doi.org/10.1007/978-3-662-59104-8_26
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-59103-1
Online ISBN: 978-3-662-59104-8
eBook Packages: Medicine (German Language)