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Special Focus on the Biology of Aging

  • Book
  • © 1991

Overview

Editors:
  1. Vincent J. Cristofalo

    1. Center for Gerontological Research, Department of Physiology and Biochemistry, Medical College of Pennsylvania, Philadelphia, USA

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  2. M. Powell Lawton
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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Overview of Biological Mechanism of Aging

    • Vincent J. Cristofalo
    Pages 1-22

  3. Genetic Diseases of Premature Aging as Models of Senescence

    • W. Ted Brown
    Pages 23-42

  4. Growth Factors and Cell Aging

    • Paul D. Phillips, David L. Doggett, Vincent J. Cristofalo
    Pages 43-52

  5. Role of Endogenous Proteins as Negative Growth Modulators During In Vitro Cellular Aging of Human Diploid Fibroblasts

    • Mary Beth Porter, James R. Smith
    Pages 53-70

  6. T-Cell Function in Aging: Mechanisms of Decline

    • Donna M. Murasko, I. Michael Goonewardene
    Pages 71-96

  7. Molecular Genetic Approaches to Mechanisms of Senescence

    • Samuel Goldstein
    Pages 97-116

  8. Altered Protein Metabolism in Aging

    • Ari Gafni
    Pages 117-131

  9. Mechanisms of Altered Hormone-Neurotransmitter Action During Aging: From Receptors to Calcium Mobilization

    • George S. Roth
    Pages 132-146

  10. Skeletal Muscle Weakness and Fatigue in Old Age: Underlying Mechanisms

    • John A. Faulkner, Susan V. Brooks, Eileen Zerba
    Pages 147-166

  11. Vulnerability of the Neuronal Cytoskeleton in Aging and Alzheimer Disease: Widespread Involvement of All Three Major Filament Systems

    • J. Q. Trojanowski, M. L. Schmidt, L. Otvos Jr., H. Arai, W. D. Hill, V. M.-Y. Lee
    Pages 167-182

  12. Dietary Restriction as a Probe of Mechanisms of Senescence

    • Edward J. Masoro, Roger J. M. McCarter
    Pages 183-197

  13. Role of Free Radicals in Senescence

    • R. G. Allen
    Pages 198-213

  14. Back Matter

    Pages 215-225
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Keywords

Editors and Affiliations

  • Center for Gerontological Research, Department of Physiology and Biochemistry, Medical College of Pennsylvania, Philadelphia, USA

    Vincent J. Cristofalo

Bibliographic Information

  • Book Title: Special Focus on the Biology of Aging

  • Editors: Vincent J. Cristofalo, M. Powell Lawton

  • DOI: https://doi.org/10.1007/978-3-662-38445-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1991

  • Softcover ISBN: 978-3-662-37652-2Published: 01 January 1991

  • eBook ISBN: 978-3-662-38445-9Published: 17 December 2013

  • Edition Number: 1

  • Number of Pages: XIII, 225

  • Number of Illustrations: 24 b/w illustrations

  • Topics: Geriatrics/Gerontology, Oxidative Stress, Aging

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