Abstract
Aspergillic acid and hydroxyaspergillic acid are antibiotics produced by certain strains of Aspergillus flavus. Chemical studies by Dutcher (1947a and b), Newbold and Spring (1947), Dunn et al. (1949a and c) and Newbold, Sharp, and Spring (1951) demonstrated that aspergillic acid has the structure shown in Fig. 1. MacDonald (1961) found that the optical configuration of the asymmetric carbon atom of the sec-butyl side chain of aspergillic acid was the same as that of carbon 3 of l-isoleucine.
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MacDonald, J.C. (1967). Aspergillic Acid and Related Compounds. In: Gottlieb, D., Shaw, P.D. (eds) Biosynthesis. Antibiotics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-38441-1_6
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DOI: https://doi.org/10.1007/978-3-662-38441-1_6
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