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Polymyxins

  • Chapter
Biosynthesis

Part of the book series: Antibiotics ((ANTIBIOTICS))

Abstract

The polymyxin group of antibiotics includes the closely related peptides polymyxin A (Ainsworth et al., 1947), polymyxin B1 and B2 (Brownlee and Jones, 1948), polymyxin C (Brownlee and Jones, 1948), polymyxin D (Benedict and Langlykke, 1947; Stansly et al.,1947), polymyxin E1 and E2 (Brown-Lee and Jones, 1948; Koyama, 1952), polymyxin M (Ilyinskaya and Rossovskaya, 1958; Khoklov et al., 1960), and circulin A and B (Murray et al., 1949). Polymyxin A was originally named aerosporin, and the antibiotic colistin (also called colimycin) is now known to be identical with polymyxin E. Polymyxins A, C and D have not been well characterized and may represent mixtures of substances.

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Authors
  1. Henry Paulus
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Editors and Affiliations

  1. Department of Plant Pathology, University of Illinois, Urbana, Illinois, USA

    David Gottlieb (Professor of Plant Pathology) (Professor of Plant Pathology)

  2. University of Illinois, Urbana, Illinois, USA

    Paul D. Shaw (Associate Professor of Biochemistry) (Associate Professor of Biochemistry)

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© 1967 Springer-Verlag Berlin Heidelberg

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Paulus, H. (1967). Polymyxins. In: Gottlieb, D., Shaw, P.D. (eds) Biosynthesis. Antibiotics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-38441-1_22

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  • DOI: https://doi.org/10.1007/978-3-662-38441-1_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-37650-8

  • Online ISBN: 978-3-662-38441-1

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