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Griseofulvin

  • Chapter
Biosynthesis

Part of the book series: Antibiotics ((ANTIBIOTICS))

Abstract

An accurate appraisal of the present state of knowledge concerning the biogenesis of griseofulvin (2 S, 6′R)-7-chloro-4,6,2′-trimethoxy-6′-methylgris-2′-en-3,4′-dione (I; R = Cl) is far from easy. The literature abounds with speculation and with statements unsupported by published detailed experimental work; and the assumption has sometimes been made that a partial biosynthetic pathway established for one griseofulvin-producing organism or strain is necessarily true of another organism or strain.

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Authors
  1. John Frederick Grove
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Editors and Affiliations

  1. Department of Plant Pathology, University of Illinois, Urbana, Illinois, USA

    David Gottlieb (Professor of Plant Pathology) (Professor of Plant Pathology)

  2. University of Illinois, Urbana, Illinois, USA

    Paul D. Shaw (Associate Professor of Biochemistry) (Associate Professor of Biochemistry)

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© 1967 Springer-Verlag Berlin Heidelberg

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Grove, J.F. (1967). Griseofulvin. In: Gottlieb, D., Shaw, P.D. (eds) Biosynthesis. Antibiotics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-38441-1_12

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  • DOI: https://doi.org/10.1007/978-3-662-38441-1_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-37650-8

  • Online ISBN: 978-3-662-38441-1

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