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Highlights of Major Differences Between Children and Adults with HIV-Associated Nephropathy

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Nephrology

Summary

Major differences between human immunodeficiency virus (HIV) associated nephropathy (HIVN) in children and HIVN in adults include the following: HIVN occurs in both HIV-1 + and AIDS adults, but apparently only in AIDS children. In HIVN patients, the virus has been transmitted to adult males mostly by intravenous drug use, and to adult females mostly by intercourse with infected males, but the virus has been transmitted to male and female infants and children by the mother. Renal histology changes in HIVN adults are mostly of the focal and segmental sclerosis (FSS) type, but FSS type changes are found in only one-third-one-half of HIVN children. The onset of chronic renal failure in adults heralds a rapid (few weeks) course to death, but in children the course is much slower (several months). Acute renal failure is rarely diagnosed in HIVN children while it is commonly diagnosed in HIVN adults.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, University of Miami School of Medicine, and Laboratory Services, Veterans Administration Medical Center (V.P.), Miami, FL, 33101, USA

    Andrea Greco

  2. Department of Pathology, University of Miami School of Medicine, and Laboratory Services, Veterans Administration Medical Center (V.P.), Miami, FL, 33101, USA

    Victoriano Pardo

Authors
  1. Jose Strauss
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  2. Gaston Zilleruelo
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  3. Carolyn Abitbol
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  4. Brenda Montane
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  5. Gwendolyn Scott
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  6. Charles Mitchell
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  7. Andrea Greco
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  8. Victoriano Pardo
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

    Michinobu Hatano M.D. (Professor of Medicine, Director) (Professor of Medicine, Director)

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© 1991 Springer Japan

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Strauss, J. et al. (1991). Highlights of Major Differences Between Children and Adults with HIV-Associated Nephropathy. In: Hatano, M. (eds) Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35158-1_43

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  • DOI: https://doi.org/10.1007/978-3-662-35158-1_43

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-70074-6

  • Online ISBN: 978-3-662-35158-1

  • eBook Packages: Springer Book Archive

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