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Intestinal Cancer

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Glycoproteins and Human Disease

Part of the book series: Medical Intelligence Unit ((MIU.LANDES))

Abstract

The biochemical and immunological properties of colon cancer mucins differ considerably from the normal. Colon cancer tissue produces glycoproteins and mucins with abnormal glycosylation patterns that may resemble fetal patterns.1–7 In addition, the genes encoding the peptide moieties of glycoproteins and mucins may undergo alterations of expression in colon cancer. These events may be related to malignant potential and development of the tumor; the mechanisms inducing these changes are still not understood.

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  1. Department of Biochemistry, Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

    Inka Brockhausen Ph.D. & William Kuhns M.S., M.D.

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Brockhausen, I., Kuhns, W. (1997). Intestinal Cancer. In: Glycoproteins and Human Disease. Medical Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-21960-7_20

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