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Morphological Classification of Malignant Lymphomas: Ultrastructural, Cytochemical and Immunological Results

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Malignant Lymphomas of the Nervous System

Part of the book series: Acta Neuropathologica ((NEUROPATHOLOGIC,volume 6))

Summary

Except for tumors clearly producing immunoglobulin (e. g. plasmacytoma), the different classes of malignant lymphomas do not correlate with a constant surface immunoglobulin pattern. Beside a prevailing IgM-surface type in a high number of different lymphoma classes even T-like or 0-cells occur in most tumor types prov. d. d they are studied in a sufficient number. The possibility of dedifferentiation of immunologic cell qualities has to be envisaged. In this context intracellular lambda-chain crystals occurring in chronic lymphocytic leukaemia may prov. d. a morphological hallmark of anaplastic deterioration of immunoglobulin synthesis. - The ambiguous significance of PAS-positive inclusions and virus-like microtubular complexes in lymphoma cells is discussed. - In conclusion the recent discovery of hairy cell leukaemia prov. d. sa good example of the value of nomenclatures based on empiricism rather than on short-liv. d. theories.

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Authors and Affiliations

  1. Abteilung für Feinstrukturelle Pathologie, Pathologisches Institut der Universität zu Köln, Josef-Stelzmannstr. 9, 5 Köln 41, Deutschland

    Prof. Dr. H. E. Schaefer, G. R. F. Krüger & R. Fischer

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  1. Prof. Dr. H. E. Schaefer
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  2. G. R. F. Krüger
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  3. R. Fischer
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  1. Wien, Austria

    K. Jellinger  & F. Seitelberger  & 

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Schaefer, H.E., Krüger, G.R.F., Fischer, R. (1975). Morphological Classification of Malignant Lymphomas: Ultrastructural, Cytochemical and Immunological Results. In: Jellinger, K., Seitelberger, F. (eds) Malignant Lymphomas of the Nervous System. Acta Neuropathologica, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08456-4_3

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  • DOI: https://doi.org/10.1007/978-3-662-08456-4_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-07208-9

  • Online ISBN: 978-3-662-08456-4

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