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Kokain

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Anästhesie in Frage und Antwort

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Zusammenfassung

Kokain

  1. 1.

    verengt die Pupillen

  2. 2.

    wird von der Plasma- und Lebercholinesterase abgebaut

  3. 3.

    hemmt die synaptische Dopaminwiederaufnahme („Re-uptake”)

  4. 4.

    kann endogene Psychosen aktivie

  5. 5.

    wirkt gefäßerweiternd

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Literatur

  • Cregler LL, Mark H (1986) Medical complications of cocaine abuse. N Engl J Med 23: 1495–1500

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  • Jensen FS, Viby-Mogensen J, Oestergard D (1991) Significance of plasma cholinesterase for the anaesthetist. Curr Anaesth Crit Care 2: 232–237

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  • Johanson CE, Fischman MW (1989) The pharmacology of cocaine related to its abuse. Pharmacol Rev 41: 3–44

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  • Taylor P (1996) Anticholinesterase agents. In: Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 9. Ed. McGraw-Hill, New York, pp 161176

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  • Wood M (1990) Cholinergic and parasympathomimetic drugs. Cholinesterases and anticholinesterases. In: Wood M, Wood AJJ (eds) Drugs and Anesthesia. Williams & Williams, Baltimore, pp 83–109

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Authors and Affiliations

  1. Fakultät für Klinische Medizin Mannheim, Institut für Pharmakologie und Toxikologie, Ruprecht-Karls-Universität Heidelberg, Maybachstraße 14-16, D-68169, Mannheim, Deutschland

    Priv.-Doz. Dr. med. Georg Petroianu

  2. Klinikum Stadt Hanau, Institut für Anästhesiologie und operative Intensivmedizin, Akademisches Lehrkrankenhaus, Johann-Wolfgang-Goethe-Universität Frankfurt, Leimenstraße 20, D-63450, Hanau, Deutschland

    Prof. Dr. med. Peter Michael Osswald

Authors
  1. Priv.-Doz. Dr. med. Georg Petroianu
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  2. Prof. Dr. med. Peter Michael Osswald
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© 2000 Springer-Verlag Berlin Heidelberg

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Petroianu, G., Osswald, P.M. (2000). Kokain. In: Anästhesie in Frage und Antwort. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05715-5_36

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  • DOI: https://doi.org/10.1007/978-3-662-05715-5_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66276-1

  • Online ISBN: 978-3-662-05715-5

  • eBook Packages: Springer Book Archive

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