Abstract
The Bamford-Stevens reaction and the Shapiro reaction share a similar mechanistic pathway. The former uses a base such as Na, NaOMe, LiH, NaH, NaNH2, etc., whereas the latter employs bases such as alkyllithiums and Grignard reagents. As a result, the Bamford-Stevens reaction furnishes more-substituted olefins as the thermodynamic products, while the Shapiro reaction generally affords less-substituted olefins as the kinetic products.
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Li, J.J. (2003). Bamford-Stevens reaction. In: Name Reactions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05336-2_15
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DOI: https://doi.org/10.1007/978-3-662-05336-2_15
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