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Clostridial Neurotoxins pp 77–87Cite as

Cellular Immunology of Tetanus Toxoid

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 195))

Abstract

Studies on tetanus neurotoxin (TeNT) as an antigen have been informative at a basic level and are continuing to expand our knowledge of what makes an effective immunogen, and how we might be able to exploit the biochemistry and physiology of antigen-presenting cells (APC) to make yet more effective immunogens. This review deals with two related aspects of TeNT as an antigen: (a) immunological responses at the T and B cell level to tetanus in humans and the possibility of exploiting tetanus in the wider context of immunotherapy, and (b) some aspects of the cell biology and biochemistry of TeNT processing in human B lymphoblastoid cells.

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Author information

Authors and Affiliations

  1. Institute de Biochimie, Universite de Lausanne, 1066, Epalinges, Switzerland

    G. Corradin

  2. Department of Biochemistry, Medical Sciences Institute, University of Dundee, DD1 4HN, Dundee, UK

    C. Watts

Authors
  1. G. Corradin
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  2. C. Watts
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Editor information

Editors and Affiliations

  1. Dipartimento di Scienze Biomediche Sperimentali, Università degli Studi di Padova, Via Trieste, 75, 35121, Padova, Italia

    Cesare Montecucco

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© 1995 Springer-Verlag Berlin Heidelberg

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Corradin, G., Watts, C. (1995). Cellular Immunology of Tetanus Toxoid. In: Montecucco, C. (eds) Clostridial Neurotoxins. Current Topics in Microbiology and Immunology, vol 195. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85173-5_4

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  • DOI: https://doi.org/10.1007/978-3-642-85173-5_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85175-9

  • Online ISBN: 978-3-642-85173-5

  • eBook Packages: Springer Book Archive

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