The Tension-Stress Effect on the Genesis and Growth of Tissues

Abstract

Our long-term medical, biologic, and engineering basic science research has led to the discovery of a general biologic law governing the stimulation of tissue growth and regeneration: the law of tensionstress. We have learned that gradual traction on living tissues creates stresses that can stimulate and maintain the regeneration of active growth of certain tissues. Slow, steady traction of tissues causes them to become metabolically activated, resulting in an increase in the proliferative and biosynthetic functions. These processes are dependent upon the adequacy of the blood supply to the tissues being elongated and the stimulating effect of weight-bearing and functional use.