Abstract
Progress in understanding the basis of recombination has lagged behind the related and overlapping areas of replication and repair for a number of reasons. For instance, the most favorable organisms for genetic analysis of recombination have not coincided with those most suitable for molecular studies. E. coli and its phages have been the prime source of molecular information, but some fairly obscure fungi have been instrumental in providing crucial genetic information about recombination. Furthermore, the phages of E. coli that were used most extensively for analysis of recombination were so different in their life cycles that it was not at all clear, at least in the beginning, that conclusions from any one of them could be generalized. Finally, recombination has not lent itself easily to dissection by biochemists because for a long time nobody could think of an adequate way to study the process. The problem was, if essentially identical chromosomes were crossed, what biochemical property could be exploited to measure the progress of the reaction?
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© 1988 Springer-Verlag Berlin Heidelberg
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Holloman, W.K. (1988). Homologous Pairing Promoted by Ustilago Rec 1 Protein. In: Eckstein, F., Lilley, D.M.J. (eds) Nucleic Acids and Molecular Biology. Nucleic Acids and Molecular Biology, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83384-7_12
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DOI: https://doi.org/10.1007/978-3-642-83384-7_12
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