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Vergleichende Endokrinologie der Fetalzeit

Comparative Endocrinology of the Fetal Period

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Endokrinologie der Entwicklung und Reifung

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Zusammenfassung

Historisch gesehen hat das Gebiet der “vergleichenden fetalen Endokrinologie” mit den grundlegenden Arbeiten von Keller und Tandler (1), und Lillie (2) seinen Anfang genommen. Diese Autoren zeigten eindrucksvoll, daß fetale Rinderzwillinge einander dann beeinflussen, wenn zwischen den chorialen Blutgefäßen Anastomosen bestehen. Die weiblichen Feten eines verschiedengeschlechtlichen Paares werden in frühen Embryonalstadien regelmäßig in später unfruchtbare Zwicken (“freemartins”) umgewandelt, ein Effekt der ausbleibt, wenn keine placentaren Anastomosen vorliegen. Hierbei werden die Müllerschen Gänge erheblich reduziert und die Ovarien strukturell so weitgehend verändert, daß sie zuweilen histologisch wie Hoden erscheinen. Gleichzeitig gehen die primordialen Germinalzellen zugrunde. Ist ein Weibchen mit zwei männlichen Feten verbunden, sind die Virilisierungsprozesse noch stärker ausgeprägt (3).

Die Arbeiten wurden durch grant HD 03298 vom National Institute for Child Health and Human Development unterstützt.

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Authors and Affiliations

  1. Dartmouth Medial School Hanover, New Hampshire, USA

    Kurt Benirschke

  2. Department of Obstetrics and Gynecology, University of California at San Diego, Cal. 92037, La Jolla, USA

    Kurt Benirschke

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  1. Kurt Benirschke
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Joachim Kracht

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Benirschke, K. (1970). Vergleichende Endokrinologie der Fetalzeit. In: Kracht, J. (eds) Endokrinologie der Entwicklung und Reifung. Symposion der Deutschen Gesellschaft für Endokrinologie in Ulm vom 26.—28. Februar 1970, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80591-2_5

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  • DOI: https://doi.org/10.1007/978-3-642-80591-2_5

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