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Vitamin-A-Säure gegen Lichtalterung

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Fortschritte der praktischen Dermatologie und Venerologie

Part of the book series: Fortschritte der praktischen Dermatologie und Venerologie ((DERMATOLOGIE,volume 13))

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Zusammenfassung

Die Geschichte der externen Therapie mit Vitamin-A-Säure (VAS) beginnt 1962 mit einer Publikation von Stüttgen [24], der über die gute Wirksamkeit dieser Behandlungsmodalität bei verschiedenen Dermatosen mit Keratinisationsstörungen berichtete. Trotz Bestätigung dieser ermutigenden Resultate durch andere Autoren, erlangte diese Therapieform, wahrscheinlich aufgrund der starken Hautirritationen durch die angewendeten hohen VAS-Konzentrationen, keine weite Verbreitung.

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Literatur

  1. Elias PM, Williams ML (1981) Retinoids, cancer, and the skin. Arch Dermatol 117: 160–180

    Article  PubMed  CAS  Google Scholar 

  2. Epstein JH, Grekin DA (1981) Inhibition of ultraviolet induced carcinogenesis by all-transretinoic acid. J Invest Dermatol 76: 178–180

    Article  PubMed  CAS  Google Scholar 

  3. Epstein JH (1986) All-trans-retinoic acid and cutaneous cancers. J Am Acad Dermatol 15: 772–778

    Article  PubMed  CAS  Google Scholar 

  4. Fuchs E, Green H (1981) Regulation of terminal differentiation of cultured human keratino-cytes by vitamin A. Cell 25: 617–625

    Article  PubMed  CAS  Google Scholar 

  5. Gilchrest B (1989) Skin aging and photoaging: An overview. J Am Acad Dermatol 21:610– 613

    Google Scholar 

  6. Grove GL, Grove MJ, Leyden JJ (1989) Optical profilometry: An objective method for quantification of facial wrinkles. J Am Acad Dermatol 21: 631–637

    Article  PubMed  CAS  Google Scholar 

  7. Haas AA, Arndt KA (1986) Selected therapeutical applications of topical tretinoin. J Am Acad Dermatol 15: 870–870

    Article  PubMed  CAS  Google Scholar 

  8. Kligman AM, Fulton JE, Plewig G (1969) Topical vitamin A acid in acne vulgaris. Arch Dermatol 99: 469–476

    Article  PubMed  CAS  Google Scholar 

  9. Kligman AM, Grove GL, Hirose R, Leyden JJ (1986) Topical tretinoin for photoaged skin. J Am Acad Dermatol 15: 836–859

    Article  PubMed  CAS  Google Scholar 

  10. Kligman LH, Akin FJ, Kligman AM (1982) Prevention of ultraviolet damage to the dermis of hairless mice by sunscreens. J Invest Derm 78: 181–189

    Article  PubMed  CAS  Google Scholar 

  11. Kligman LH, Chen HD, Kligman AM (1982) Topical retinoic acid enhances the repair of ultraviolet damaged connective tissue. Connect Tissue Res 12: 139–150

    Article  Google Scholar 

  12. Kligman LH (1986) Effects of all-trans-retinoic acid on the dermis of hairless mice. J Am Acad Dermatol (suppl) 15: 779–785

    Article  CAS  Google Scholar 

  13. Kligman LH, Kligman AM (1986) The nature of photoaging: Its prevention and repair. Photodermatol 3:215 - 227

    Google Scholar 

  14. Kligman LH (1987) Retinoic acid and photocarcinogenesis — a controversy. Photodermatol 4: 88–101

    PubMed  CAS  Google Scholar 

  15. Kligman LH, Gebre M, Alper R, Kephalides NA (1989) Collagen metabolism in ultraviolet irradiated hairless mouse skin and its correlation to histochemical observations. J Invest Dermatol 93: 210–214

    Article  PubMed  CAS  Google Scholar 

  16. Kraemer KH, Di Giovanna JJ, Moshel AN, Tarone RE, Peck GL (1988) Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin. N Engl J Med 318: 1633–1637

    Article  PubMed  CAS  Google Scholar 

  17. Krieg T, Braun-Falco O (1990) Retinoide zur Behandlung von Hautfalten. Eine kritische Stellungnahme. Hautarzt 41: 183–187

    PubMed  CAS  Google Scholar 

  18. Lavker RM (1979) Structural alteration in exposed and unexposed aged skin. J Invest Dermatol 73: 59–66

    Article  PubMed  CAS  Google Scholar 

  19. Leyden JJ, Grove GL, Grove MJ, Thorne EG, Lufrano L (1989) Treatment of photodamaged facial skin with topical tretinoin. J Am Acad Dermatol 21: 638–644

    Article  PubMed  CAS  Google Scholar 

  20. Lever L, Kumar P, Marks R (1990) Topical retinoic acid for treatment of solar damage. Br J Dermatol 122: 91–98

    Article  PubMed  CAS  Google Scholar 

  21. Olsen EA, Katz I, Levine N, Shupak J, McCarley MB, Prawer ST, Gold J, Stiller M, Lufrano L, Thorne EG (1992) Tretinoin emollient cream: A new therapy for photodamaged skin. J Am Acad Dermatol 26: 215–224

    Article  PubMed  CAS  Google Scholar 

  22. Panizzon R, Bruckner-Tudermann L, Mindek G, Burg G (1992) Tretinoin bei lichtgeschä-digter Haut: Erste experimentelle Untersuchungsergebnisse. Hautnah derm 3: 300–306

    Google Scholar 

  23. Roberts L (1988) Questions raised about anti-wrinkle cream. Science 239: 564

    Article  PubMed  CAS  Google Scholar 

  24. Stüttgen G (1962) Zur Lokalbehandlung von Keratosen mit Vitamin A Säure. Dermatologica 124: 65–80

    Article  Google Scholar 

  25. Uitto J, Fazio MJ, Olsen D (1989) Molecular mechanisms of cutaneous aging. J Am Acad Dermatol 21: 614–622

    Article  PubMed  CAS  Google Scholar 

  26. Urbach F, Forbes PD, Davies RE (1982) Modifications of photocarcinogenesis by chemical agents. JNCI 69: 229–235

    PubMed  CAS  Google Scholar 

  27. Weinstein GD, Nigra T, Pochi EP, Savin P, Allan A, Benik B, Jeffes E, Lufrano L, Thorne G (1991) Topical Tretinoin for treatment of photodamaged skin. Arch Dermatol 127: 659–665

    Article  PubMed  CAS  Google Scholar 

  28. Weiss JS, Ellis CN, Headington JT, Tincoff T, Hamilton TA, Voorhees JJ (1988) Topical Tretinoin improves photoaged skin. A double-blind vehicle controlled study. JAMA 259: 527–532

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. Percy Lehmann
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Editors and Affiliations

  1. Dermatologischen Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Frauenlobstraße 9-11, D 80337, München, Deutschland

    Otto Braun-Falco (Professor für Dermatologie und Venerologie, vorm. Direktor), Gerd Plewig (Professor für Dermatologie und Venerologie, Direktor ) & Michael Meurer (Professor für Dermatologie und Venerologie) (Professor für Dermatologie und Venerologie, vorm. Direktor),  (Professor für Dermatologie und Venerologie, Direktor ) &  (Professor für Dermatologie und Venerologie)

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© 1993 Springer-Verlag Berlin Heidelberg

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Lehmann, P. (1993). Vitamin-A-Säure gegen Lichtalterung. In: Braun-Falco, O., Plewig, G., Meurer, M. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 13. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78163-6_57

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  • DOI: https://doi.org/10.1007/978-3-642-78163-6_57

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56590-1

  • Online ISBN: 978-3-642-78163-6

  • eBook Packages: Springer Book Archive

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