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Side Reactions in Peptide Synthesis

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Principles of Peptide Synthesis

Part of the book series: Springer Laboratory ((SLM))

Abstract

In two reviews the authors attempted a systematic discussion of side reactions encountered in peptide synthesis. The first of these articles [1] was organized according to side reactions characteristic for a particular residue. Of the twenty amino acid constituents of proteins only alanine and leucine are immune from characteristic side reactions, although not from racemization. The second, more comprehensive article [2] contains also a treatment of side reactions associated with methods of protection and coupling. In this volume, in which an attempt is being made to discern the principles that govern peptide synthesis, side reactions proceeding through similar mechanisms are grouped together. Racemization will be treated together with other undesired reactions in the same manner.

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    Professor Dr. Miklos Bodanszky

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Bodanszky, M. (1993). Side Reactions in Peptide Synthesis. In: Principles of Peptide Synthesis. Springer Laboratory. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78056-1_5

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