Abstract
It is established that neurotransmitters in general and serotonin (5HT) in particular have a trophic role in the maturation of the central nervous system (CNS) (Lauder 1983). This action could be mediated in part via regulation of glia since neuron—glia interactions are necessary for the maturation of both neurons and glia (Hatten and Mason 1986; Holton and Weston 1982; Le Prince et al. 1990) and since glial cells in the CNS possess receptors for neurotransmitters (Whitaker-Azmitia 1988).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bouchaud C, Arluison M (1977) Serotoninergic innervation of ependymal cells in the rat subcommissural organ; a fluorescence electron microscopic and radioautographic study. Biol Cell 30: 65–72
Chouaf L, Didier-Bazes M, Aguera M, Tardy M, Sallanon M, Kitahama K, Belin MF (1989) Comparative marker analysis of the ependymocytes of the subcommissural organ in four different mammalian species. Cell Tissue Res 257: 255–262
Chouaf L, Didier-Bazes M, Hardin H, Aguera M, Fevre-Montange M, Voutsinos B, Belin MF (1991) Developmental expression of glial markers in subcommissural organ ependymocytes of the rat: role of the environment. Cell Tissue Res 266: 553–561
Didier M, Harandi M, Aguera M, Bancel B, Tardy M, Fages C, Calas A, Stagaard M, Møllgård DK, Belin MF (1986) Differential immunocytochemical staining for glial fibrillary acidic (GFA) protein, S100 protein and glutamine synthetase in the rat subcommissural organ and non specialized ventricular ependyma and adjacent neuropil. Cell Tissue Res 245: 243–351
Didier-Bazes M, Aguera M, Chouaf L, Harandi M, Calas A, Meiniel A, Belin MF (1989) Neuronal control of [3H] GABA uptake in the ependymocytes of the subcommissural organ: an in vivo model of neuron-glia interaction. Brain Res 489: 137–145
Didier-Bazes M, Chouaf L, Hardin H, Aguera M, Fèvre-Montange M, Belin MF (1991) Developmental neuron-glia interaction: role of the serotonin innervation upon the onset of GABA uptake into the ependymocytes of the rat subcommissural organ. Dev Brain Res 63: 135–139
Gamrani H, Belin MF, Aguera M, Calas A, Pujol JF (1981) Radioautographic evidence for an innervation of the subcommissural organ by GABA-containing nerve fibres. J Neurocytol 10: 411–424
Hatten ME, Mason CA (1986) Neuron-astroglia interactions in vitro and in vivo. Trends Neurosci 9: 168–174
Holton B, Weston J (1982) Analysis of glial cell differentiation in peripheral nervous tissue. II. Neurons promote S-100 synthesis by purified glial precursor cell populations. Dev Biol 89: 72–81
Lauder JM, Wallace JA, Krebs H, Petruz P, Mc Carthy K (1982) In vivo and in vitro development of serotonergic neurons. Brain Res Bull 9: 605–625
Lauder JM (1983) Hormonal and humoral influences on brain development. Psychoneuroendocrinology 8: 121–155
Léger L, Degueurce A, Lundberg JJ, Pujol JF, Møllgård K (1983) Origin and influence of the serotoninergic innervation of the subcommissural organ in the rat. Neuroscience 2: 411–423
Lepetit P, Touret M, Grange E, Gay N, Bobillier P (1991) Inhibition of methionine incorporation into brain proteins after the systemic administration of p-chlorophenylalanine and L-5-hydroxytryptophan. Eur J Pharmacol 209: 207–212
Le Prince G, Copin MC, Hardin H, Belin MF, Bouilloux JP, Tardy M (1990) Neuron-glia interactions: effect of serotonin on the astroglial expression of GFAP and of its encoding message. Dev Brain Res 51: 295–298
Lestage P, Gonon M, Lepetit P, Vitte PA, Debilly G, Rossatto C, Lecestre D, Bobillier P (1987) An in vivo kinetic model with L-35S-methionine for the determination of local cerebral rates of methionine incorporation into protein in the rat. J Neurochem 48: 352–363
Marcinkiewicz M, Bouchaud C (1986) Formation and maturation of axo-glandular synapses and concomitant changes in the target cells of the rat subcommissural organ. Biol Cell 56: 57–65
Redecker P (1989) Immunohistochemical localisation of glial fibrillary acidic protein (GFAP) and vimentin in the subcommissural organ of the Mongolian gerbil (Meriones unguiculatus). Cell Tissue Res 255: 595–600
Reynolds R, Herschkowitz N (1987) Oligodendroglial and astroglial heterogeneity in mouse primary central nervous system culture as demonstrated by differences in GABA and D-aspartate transport and immunocytochemistry. Dev Brain Res 36: 13–25
Schousboe A, Drejer J, Meier E, Larsson OM, Schousboe I (1986) Regional heterogeneity of astrocytic transport processes for glutamate and GABA. Adv Biosci 61: 225–233
Whitaker-Azmitia PM (1988) Astroglial serotonin receptors. In: Kimelberg HK (ed) Glial cell receptors. Raven, New York, pp 107–120
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Didier-Bazes, M., Chouaf, L., Lepetit, P., Aguera, M., Belin, M.F. (1993). The Subcommissural Organ of the Rat: An In Vivo Model of Neuron—Glia Interactions. In: Oksche, A., Rodríguez, E.M., Fernández-Llebrez, P. (eds) The Subcommissural Organ. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78013-4_18
Download citation
DOI: https://doi.org/10.1007/978-3-642-78013-4_18
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-78015-8
Online ISBN: 978-3-642-78013-4
eBook Packages: Springer Book Archive