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Lectins as Analytical Probes to Define the Physical Characteristics of Binding Events

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Lectins and Glycobiology

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Abstract

The lectins’ remarkable molecular homogeneity and adequate affinity constants make them excellent candidates for development as analytical reagents. If one makes the assumption that the binding target is carbohydrate (C) and the binder is lectin (L), then the simplest bimolecular reaction can be represented by:

$$\text{C}_j + \text{L}_i \rightleftarrows \text{CL}_{ij} ,\;\;\;k_{ij} = \frac{{[\text{CL}_{ij} ]}} {{[\text{C}_j ][\text{L}_i ]}}.$$

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References

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Authors
  1. P. L. Mann
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  2. C. Hanosh
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  3. C. M. Tellez
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  4. R. Wenk
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  5. R. Diaz
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Editors and Affiliations

  1. Institut für Physiologische Chemie, Ludwig-Maximilians-Universität, Veterinärstraße 13, D-80539, München, Germany

    Hans-Joachim Gabius  & Sigrun Gabius  & 

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© 1993 Springer-Verlag Berlin Heidelberg

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Mann, P.L., Hanosh, C., Tellez, C.M., Wenk, R., Diaz, R. (1993). Lectins as Analytical Probes to Define the Physical Characteristics of Binding Events. In: Gabius, HJ., Gabius, S. (eds) Lectins and Glycobiology. Springer Laboratory. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77944-2_13

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  • DOI: https://doi.org/10.1007/978-3-642-77944-2_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77946-6

  • Online ISBN: 978-3-642-77944-2

  • eBook Packages: Springer Book Archive

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