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Case Definition: Issues Related to Monoclonal Gammopathies and Multiple Myeloma

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Epidemiology and Biology of Multiple Myeloma

Abstract

During 1988, 808 patients were found with a serum monoclonal protein (M-protein) at the Mayo Clinic. The most frequent clinical diagnosis was monoclonal gammopathy of undetermined significance (MGUS) (benign monoclonal gammopathy), 64%. Other diagnoses were multiple myeloma (MM), 14%; primary systemic amyloidosis (AL), 8%; lymphoproliterative disease including lymphoma and macroglobulinemia, 8%; chronic lymphocytic leukemia, 2%; smoldering multiple myeloma (SMM), 2%; and solitary or extramedullary plasmacytoma, 2%.

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© 1991 Springer-Verlag Berlin Heidelberg

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Kyle, R.A. (1991). Case Definition: Issues Related to Monoclonal Gammopathies and Multiple Myeloma. In: Obrams, G.I., Potter, M. (eds) Epidemiology and Biology of Multiple Myeloma. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76655-8_13

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  • DOI: https://doi.org/10.1007/978-3-642-76655-8_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-76657-2

  • Online ISBN: 978-3-642-76655-8

  • eBook Packages: Springer Book Archive

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