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Understanding the Mechanisms of Cure in Acute Myeloblastic Leukaemia: Towards a Modern Immunotherapy

  • Conference paper
Acute Leukemias

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 34))

  • 67 Accesses

Abstract

The published literature suggests that less than 25% of patients with de novo acute myeloblastic leukaemia (AML), treated by intensive chemotherapy, are cured by this approach [1, 2]. Modest improvements have been claimed for treatment on high-dose cytosine arabinoside (HD-Ara-C) containing combinations [3] and in younger patients on the VAPA protocol [4]. As a rule more than 60% experience disease recurrence [5, 2].

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Author information

Authors and Affiliations

  1. Bone Marrow Transplant Programme, Royal Free Hospital School of Medicine, London, UK

    H. G. Prentice

Authors
  1. H. G. Prentice
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine, University of Münster, Albert-Schweitzer-Straße 33, D-4400, Münster, Federal Republic of Germany

    W. Hiddemann , T. Büchner  & B. Wörmann ,  & 

  2. M. D. Anderson Cancer Center, University of Texas, 1515 Holocombe Boulevard, 77030, Houston, TX, USA

    W. Plunkett , M. Keating  & M. Andreeff ,  & 

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© 1992 Springer-Verlag Berlin Heidelberg

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Prentice, H.G. (1992). Understanding the Mechanisms of Cure in Acute Myeloblastic Leukaemia: Towards a Modern Immunotherapy. In: Hiddemann, W., Büchner, T., Wörmann, B., Plunkett, W., Keating, M., Andreeff, M. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 34. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76591-9_98

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  • DOI: https://doi.org/10.1007/978-3-642-76591-9_98

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53949-0

  • Online ISBN: 978-3-642-76591-9

  • eBook Packages: Springer Book Archive

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