Abstract
Syntropic manifestations of autoimmune diseases are found in various organs. Of these pluriglandular syndromes, Schmidt’s syndrome — autoimmune thyroiditis associated with autoimmune adrenalitis — is a well-known example of dual organ involvement [18]. The extension of Schmidt’s syndrome to chronic insulitis with insulin-dependent diabetes mellitus was described by Carpenter and coworkers in 1964 [4]. As early as 1907 Claude and Gougerot, on the basis of clinical and pathological observations, had coined the concept of “pluriglandular insufficiency” [6], and in 1912 Falta observed the variability of the “multiple sclerosis of blood glands” [8]. In 1930 Ostertag reported the association of calcification in the basal ganglia with tetany, hypothyroidism, pernicious anemia, and Addison’s disease [16].
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Seif, F.J. (1991). Autoimmune Thyroiditis: Its Implications with Other Organ Systems. In: Scherbaum, W.A., Bogner, U., Weinheimer, B., Bottazzo, G.F. (eds) Autoimmune Thyroiditis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76301-4_6
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DOI: https://doi.org/10.1007/978-3-642-76301-4_6
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