Abstract
The morphological changes of the pancreatic ductal system in chronic alcohol-induced pancreatitis (AIP) usually follow a progressive course with the development of pancreatic duct stones, strictures and obstructions, and dilatation of the pancreatic duct [11]. There is a perception that these changes cause obstruction to the flow of pancreatic juice, leading to pancreatic duct hypertension and pain. Available data on the correlation between these changes and pain, however, do not substantiate this seemingly logical hypothesis. Patients with pancreatic duct strictures or obstructions (PDSOs) may or may not have associated duct dilatation and, conversely, pancreatic duct dilatation (PDD) may be unassociated with PDSO.
Support from the South African Medical Research Council is acknowledged
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References
Ammann RW, Largiader F, Akovbiantz A (1979) Pain relief by surgery in chronic pancreatitis. Scand J Gastroenterol 14:209–215
Ammann RW, Akovbiantz, A, Largiader F, Schneier G (1981) Course and outcome of chronic pancreatitis. Gastroenterology 86:820–828
Bornman PC, Marks IN, Girdwood AH, et al. (1980) Is pancreatic duct obstruction or stricture a major cause of pain in calcific pancreatitis? Br J Surg 76:425–428
Bornman PC, Girdwood AH, Marks IN, Hatfield ARW (1982) The influence of continued alcohol intake, pancreatic duct hold-up and pancreatic insufficiency on the pain pattern in chronic non-calcific and calcific pancreatitis: a comparative study. Surg Gastroenterol 1:5–9
Girdwood AH, Marks IN, Bornman PC, Kottler RE, Cohen M (1981) Does progressive pancreatic insufficiency limit pain in calcific pancreatitis with duct stricture or continue alcohol insult? J Clin Gastroenterol 3:241–245
Girdwood AH, Bornman PC, Marks IN (1988) Intractable pain in alcohol induced pancreatitis. Can one wait for the pancreas to burn itself out? Int J Pancreatol [Suppl 2] 3:S244
Holmberg JT, Isaksson G, Ihse I (1985) Longterm results of pancreatico-jejunostomy in chronic pancreatitis. Surg Gynecol Obstet 160:339–346
Jensen AR, Matzen P, Malchow-Møller A, Christoffersen I (1984) The Copenhagen Pancreatitis Study Group. Pattern of pain, duct morphology, and pancreatic function in chronic pancreatitis. Scand J Gastroenterol 19:334–338
Leger L, Lenroit JP, Lemaigre G (1974) Five to twenty year follow-up after surgery for chronic pancreatitis in 148 patients. Ann Surg 180:185–191
Malfertheiner P, Büchler M, Stanescu A, Ditschuneit H (1987) Pancreatic morphology and function in relationship to pain in chronic pancreatitis. Int J Pancreatol 1:59–66
Nagata A, Homma T, Tamai K, et al. (1981) A study of chronic pancreatititis by serial endoscopic pancreatography. Gastroenterology 81:884–891
Nieuwoudt JHM, Girdwood AH, Bornman PC, Marks IN (1986) The correlation between pancreatic duct size and pain in chronic pancreatitis. S Afr J Surg 24:124
Prinz RA, Greenlee HB (1981) Pancreatic duct drainage in 100 patients with chronic pancreatitis. Ann Surg 194:313–318
White TT, Slavotinek AH (1979) Results of surgical treatment of chronic pancreatitis: report of 142 cases. Ann Surg 138:129–133
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© 1990 Springer-Verlag Berlin Heidelberg
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Girdwood, A.H., Bornman, P.C., Marks, I.N. (1990). Ductal Morphology and Pain in Chronic Alcohol-Induced Pancreatitis. In: Beger, H.G., Büchler, M., Ditschuneit, H., Malfertheiner, P. (eds) Chronic Pancreatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75319-0_26
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DOI: https://doi.org/10.1007/978-3-642-75319-0_26
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