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Positron Emission Tomography in Schizophrenia

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Search for the Causes of Schizophrenia

Abstract

During the last two decades several brain imaging techniques have been introduced into psychiatric research allowing the study of various aspects of brain function and structure in relation to disease and treatment. Of these, positron emission tomography (PET) is the most powerful. In PET, radioactive tracers make it possible to study regional biochemistry and neuroreceptors in the living human brain. So far most PET studies in schizophrenia have dealt with regional glucose metabolism and have increased our knowledge of brain function in this severe disease. A new field of application to psychiatric research is the study of neuroreceptor characteristics and thus of mechanisms of action of psychotropic drugs.

This study was supplied by grants from the Swedish Medical Research Council (07027, 08318), The Bank of Sweden Tercentenary Fondation and the US National Institute of Mental Health.

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Wiesel, FA., Farde, L., Nordström, AL., Sedvall, G., Wik, G. (1990). Positron Emission Tomography in Schizophrenia. In: Häfner, H., Gattaz, W.F. (eds) Search for the Causes of Schizophrenia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74881-3_22

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